Rchr
J-GLOBAL ID:200901075812631894
Update date: Aug. 28, 2024
Imagawa Masayoshi
イマガワ マサヨシ | Imagawa Masayoshi
Affiliation and department:
Job title:
Specially Appointed Professor, Director
Homepage URL (1):
http://www.nagoya-cu.ac.jp/affiliate/institutes/ncu-22seikikenkyujo/index.html
Research field (2):
Pharmacology
, Pharmaceuticals - health and biochemistry
Research keywords (8):
転写
, 糖尿病
, 脂肪細胞分化
, 肥満
, transcription
, diabetes
, adipocyte differentiation
, obesity
Research theme for competitive and other funds (33):
- 2016 - 2018 脂肪細胞分化を制御する新規遺伝子が有する新たな生理機能の解明
- 2009 - 2012 Molecular mechanisms of the signal transductions by the factors functioning as a trigger for the adipocyte differentiation.
- 2006 - 2007 脂肪細胞分化初期に機能する新規因子群のシグナル伝達連関の解明
- 2004 - 2005 脂肪細胞分化初期に機能する因子群のシグナル伝達機構
- 2003 - 2004 内臓脂肪と皮下脂肪の機能の違いを規定する因子群の分子生物学的検討
- 2002 - 2004 Effect of endocrine disruptors on nuclear receptor superfamily.
- 2002 - 2003 脂肪細胞分化におけるclonal expansionと分化シグナルの切り換え機構
- 2001 - 2003 水環境汚染評価のための新バイオマーカー
- 1999 - 2002 Development of New Screening Method for Endocrine Disruptors and Analyses of Disrupting Mechanisms
- 2000 - 2000 環境化学物質が肥満を誘発する可能性
- 1998 - 1999 Identification of transcription factor related to toxicity of dioxin
- 1997 - 1999 Molecular mechanisms of negative regulation on gene expression.
- 1994 - 1997 Role of three dimensional structure of proteins in signal transduction
- 1997 - 脂肪細胞分化の分子機構
- 1997 - Molecular mechanisms of adipocyte differentiation
- 1995 - 1995 アルツハイマー病における神経成長抑制因子の発現制御機構
- 1995 - 1995 サイレンサーの機能制御
- 1994 - 1994 サイレンサー結合蛋白質の機能制御機構
- 1993 - 1994 Regulation mechanisms of glutathione transferase gene expression during hepatocarcinogenesis
- 1993 - 1993 サイレンサー結合蛋白質の機能制御機構
- 1992 - 1992 遺伝子調節機構の立体構造とダイナミクスの研究調査
- 1991 - 1992 Mechanisms of specific expression of glutathione transferase gene during hepatocarcinogenesis
- 1991 - 1991 制御蛋白質の機能構造
- 1991 - 1991 グルタチオン・トランスフェラ-ゼP遺伝子の肝癌特異的発現機構
- 1990 - 1990 制御蛋白質の機能構造
- 1990 - 1990 グルタチオン・トランスフェラ-ゼP遺伝子の肝癌特異的発現機構
- 1988 - 1990 真核生物リボソ-ム遺伝子の発現制御機構
- 1988 - 1988 ヒト・線虫・酵母メタロチオネイン遺伝子における転写制御因子
- 1986 - 1987 Study of morphogenesis of spore coat of Bacillus megaterium
- 核内ホルモン受容体の作用機構
- 肥満に起因する病態発生の分子機構
- 発癌過程における遺伝子発現機構
- Regulation mechanisms of gene expression during carcinogenesis
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Papers (64):
-
Makoto Nishizuka, Rina Komada, Masayoshi Imagawa. Knockdown of RhoE Expression Enhances TGF-β-Induced EMT (epithelial-to-mesenchymal transition) in Cervical Cancer HeLa Cells. International Journal of Molecular Sciences. 2019. 20. 19
-
Motoharu Goto, Shigehiro Osada, Masayoshi Imagawa, Makoto Nishizuka. FAD104, a regulator of adipogenesis, is a novel suppressor of TGF-beta-mediated EMT in cervical cancer cells. SCIENTIFIC REPORTS. 2017. 7
-
Makoto Nishizuka, Wataru Horinouchi, Eri Yamada, Natsuki Ochiai, Shigehiro Osada, Masayoshi Imagawa. KCNMA1, a pore-forming -subunit of BK channels, regulates insulin signalling in mature adipocytes. FEBS LETTERS. 2016. 590. 23. 4372-4380
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Daiki Katoh, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa. FAD104, a Regulator of Adipogenesis and Osteogenesis, Interacts with the C-Terminal Region of STAT3 and Represses Malignant Transformation of Melanoma Cells. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2016. 39. 5. 849-855
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Natsuki Ochiai, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa. Fad24, a Positive Regulator of Adipogenesis, Is Required for S Phase Re-entry of C2C12 Myoblasts Arrested in G0 Phase and Involved in p27(Kip1) Expression at the Protein Level. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2016. 39. 5. 807-814
more...
MISC (147):
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Masayoshi Imagawa. Molecular Mechanisms of Early-stage Adipocyte Differentiation and Multi-functional Roles of Newly Isolated Adipogenic Factors. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. 2016. 136. 4. 649-658
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M. Goto, M. Nishizuka, S. Osada, M. Imagawa. The role of fad104, a positive regulator for adipogenesis, in TGF-beta 1-induced epithelial to mesenchymal transition. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
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M. Nishizuka, W. Horinouchi, E. Yamada, S. Osada, M. Imagawa. KCNMA1 contributes to the regulation of insulin signalling in mature adipocytes. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
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N. Ochiai, M. Nishizuka, S. Osada, M. Imagawa. The role of fad24, a positive regulator for adipogenesis, in early embryonic development and muscle cell activation. FEBS JOURNAL. 2015. 282. 286-286
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M. Nishizuka, W. Horinouchi, E. Yamada, S. Osada, M. Imagawa. The role of KCNMA1 in mature adipocytes. FEBS JOURNAL. 2015. 282. 285-285
more...
Books (3):
-
生活習慣病の分子生物学(共著)
三共出版 2007
-
肥満は万病のもと -体脂肪を知るー
丸善 2001
-
Stringent integrity requirements for both transactivation and DNA-binding in a trans-activator, Oct 3"jointly worked"
Nucleic Acids Research 2001
Education (5):
- 1977 - 1980 Osaka University Graduate School of Pharmaceutical Sciences
- - 1980 Osaka University Graduate School, Division of Pharmaceutical Sciences
- 1975 - 1977 Chiba University Graduate School of Pharmaceutical Sciences
- 1971 - 1975 Chiba University Faculty of Pharmaceutical Sciences
- - 1975 Chiba University Faculty of Pharmaceutical Science
Professional career (1):
- (BLANK) (Osaka University)
Work history (12):
- 2017/04 - 現在 Nagoya City University
- 2013/04 - 現在 Nagoya City University
- 2000/03 - 2017/03 Nagoya City University
- 1992 - 2000 Osaka University School of Pharmaceutical Sciences
- 1992 - 2000 Osaka University
- 2000 - - Nagoya City University
- 1988 - 1992 The University of Tokyo Faculty of Medicine
- 1988 - 1992 The University of Tokyo
- 1984 - 1988 Osaka University School of Pharmaceutical Sciences
- 1984 - 1988 Osaka University
- 1980 - 1984 Miyazaki Medical College
- 1980 - 1984 Medical College of Miyazaki
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Awards (2):
- 2015 - 平成27年度日本薬学会学術貢献賞
- 1996 - 平成8年度日本薬学会奨励賞
Association Membership(s) (7):
日本細菌学会
, 日本神経化学会
, 米国微生物学会(American Society for Microbiology)
, 日本分子生物学会
, 日本生化学会
, 日本癌学会
, 日本薬学会
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