Rchr
J-GLOBAL ID:200901076512373334
Update date: Jul. 11, 2024
Nakamura Eijiro
ナカムラ エイジロウ | Nakamura Eijiro
Affiliation and department:
Job title:
Assistant chief
Research field (1):
Urology
Research keywords (4):
国際共同治験
, 創薬
, 泌尿器科学
, GU Oncology
Research theme for competitive and other funds (27):
- 2022 - 2025 空間的オミクス技術による非淡明細胞型腎細胞癌の腫瘍エコシステムの包括的解明
- 2020 - 2023 次世代ヒト化シンジェニックマウスによる腎癌免疫ニッチの再現と治療評価モデルの樹立
- 2017 - 2020 Development of new VHL disease models using patient-derived iPS cells
- 2016 - 2018 Identification of the novel therapeutic targets for CRPC by using newly developed AR-V7 expressing prostate cancer cell lines
- 2015 - 2018 Development of predictive markers for drug-susceptibility in blood by genomic analysis using PDX models
- 2014 - 2017 Identification of causative genes for hemangioblastoma to elucidate the mechanisms of neovascularization and to develop novel therapeutic strategies
- 2014 - 2016 Identification of new therapiutic molecules for CRPC by using library screening methods
- 2012 - 2014 Identification of new therapeutic target molecules for renal cell carcinoma
- 2008 - 2010 Molecular mechanism of urothelium regulating bladder function
- 2008 - 2010 Research for a mechanism of prostate cancer metastasis through a SPA-1(Rap1GAP) signaling pathway.
- 2006 - 2009 Validation of OMICS data of urological malignancies for the clinical use
- 2007 - 2008 Receptor mediated gene therapy targetting to bladder upon nanoscale vector complex
- 2007 - 2008 Mechanisms of acquiring androgen-independence in novel prostate cancer xenograft model
- 2007 - 2007 smallGproteinを介した新たな癌転移機構の解明
- 2006 - 2007 治療アウトカムに立脚した泌尿器科がんの治療応答性予測のための分子マーカーの開発
- 2006 - 2007 Tumor microvasculature with endothelial fenestrations as a potent predictive marker and target of anti-VEGF therapy in clear cell renal cell carcinoma
- 2005 - 2007 Identification and validation of tumor biomarkers for urogenital cancer using proteomic analysis of cell culture supernatant
- 2005 - 2006 New therapy for renal cell carcinoma with down regulation of glycosyltransferase gene
- 2003 - 2004 Functional and Expression Analyses of Endoplasmic Reticulum Stress Response Genes in Prostate Cancer
- 2003 - 2004 アンドロゲン依存性コレステロール合成系酵素DHCR24の前立腺癌における機能解析
- 2001 - 2001 分子疫学的手法を用いた前立腺癌の発生リスクに関与する因子の同定とその臨床応用
- 2000 - 2001 遺伝子多型解析による腎細胞癌患者の予後、治療効果に関する研究
- 1999 - 2001 Relationship between ureteral bud and metanephric mesenchyme in mouse embryo
- 2000 - 2000 分子疫学的手法を用いた前立腺癌の発生リスクに関与する因子の同定とその臨床応用
- 1998 - 2000 Epigenetic change associate with the development of urogenital tumors
- 遺伝子多型解析による腎細胞癌患者の予後,治療効果に関する臨床研究
- Roles of genetic polymorphisms on the prognosis of RCC patients
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Papers (73):
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Takashi Matsuoka, Aiko Sugiyama, Yoshifumi Miyawaki, Yusuke Hidaka, Yukiko Okuno, Hiroaki Sakai, Hiroki Tanaka, Kiyotsugu Yoshikawa, Tomohiro Fukui, Kei Mizuno, et al. Newly developed preclinical models reveal broad-spectrum CDK inhibitors as potent drugs for CRPC exhibiting primary resistance to enzalutamide. Cancer science. 2023
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Ayako Takahashi, Yuki Muraoka, Sho Koyasu, Yoshiki Arakawa, Eijiro Nakamura, Akitaka Tsujikawa. Novel Manifestation of Retinal Hemangioblastomas Detected by OCT Angiography in von Hippel-Lindau Disease. Ophthalmology. 2023. 130. 7. 748-755
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Hajime Takamori, Toshinari Yamasaki, Rui Kitadai, Yoji Andrew Minamishima, Eijiro Nakamura. Development of drugs targeting hypoxia-inducible factor against tumor cells with VHL mutation: Story of 127 years. Cancer science. 2023. 114. 4. 1208-1217
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Masato Yonamine, Koichiro Wasano, Yuichi Aita, Takehito Sugasawa, Katsutoshi Takahashi, Yasushi Kawakami, Hitoshi Shimano, Hiroyuki Nishiyama, Hisato Hara, Mitsuhide Naruse, et al. Prevalence of Germline Variants in a Large Cohort of Japanese Patients with Pheochromocytoma and/or Paraganglioma. Cancers. 2021. 13. 16
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Takayuki Sumiyoshi, Toshinari Yamasaki, Masashi Takeda, Kei Mizuno, Noriaki Utsunomiya, Hiromasa Sakamoto, Eijiro Nakamura, Osamu Ogawa, Shusuke Akamatsu. Detection of von Hippel-Lindau gene mutation in circulating cell-free DNA for clear cell renal cell carcinoma. Cancer science. 2021. 112. 8. 3363-3374
more...
MISC (38):
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桐澤 崇宏, 今井 亨, 中村 英二郎. 特集 どこまで変わるの? 腎細胞癌診療の進歩 〈薬物治療〉 VHL遺伝子変異を標的とした創薬-HIF-2α阻害薬の開発. 臨床泌尿器科. 2023. 77. 5. 388-393
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TAKAMORI Hajime, UETANI Masato, YOSHIDA Tatsuya, BAN Daisuke, NAKAMURA Eijiro, FUJIMOTO Hiroyuki, MATSUI Yoshiyuki. A Case of Metastatic Adrenal Tumor with Liver Infiltration which was Successfully Resected by Laparoscopic Surgery Using Both Intraperitoneal and Retroperitoneal Approaches. 2022. 68. 6. 179-183
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上谷 将人, 奥野 智也, 中村 英二郎. 低酸素応答を標的とした癌治療-Recent advances of therapeutic strategy against cancer cells targeting hypoxic responses-特集 低酸素生物学の新展開. 細胞. 2022. 54. 7. 372-375
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高森 一, 中村 英二郎. 悪性褐色細胞腫・パラガングリオーマ-JOURNAL IN JOURNAL : Focus On Your Direction 泌尿器科 専門領域の最新情報(vol.10)希少がん. 泌尿器care & cure uro-lo : 治療と看護みんなつながるマガジン. 2021. 26. 5. 732-736
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腎細胞癌における治療開発の将来展望. 2021. 75. 2. 146-150
more...
Education (7):
Professional career (1):
Association Membership(s) (8):
日本遺伝性腫瘍学会(評議員)
, 日本癌学会(評議員)
, 腎癌研究会(学術評議員)
, 米国臨床腫瘍学会
, 日本臨床腫瘍学会
, 日本癌治療学会
, 日本泌尿器腫瘍学会
, 日本泌尿器科学会(指導医・専門医)
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