Rchr
J-GLOBAL ID:200901076557878917   Update date: May. 17, 2024

Naoki Sakai

サカイ ナオキ | Naoki Sakai
Affiliation and department:
Job title: Senior scientist
Research field  (1): Structural biochemistry
Research keywords  (4): X線結晶学 ,  構造生物学 ,  Macromolecule crystallography ,  Structural biology
Research theme for competitive and other funds  (5):
  • 2022 - 2024 コムギ無細胞系とAirIDを基盤とした複合体生産・探索・解析技術の支援と高度化
  • 2010 - 2012 幅広いインフルエンザHA亜型を認識する抗体とHA複合体の構造生物学的研究
  • 2008 - 2009 The structural biological study of the macromolecular complex involved with formation of SARS-CoV virions
  • 2007 - 2008 腸内細菌の病原性・非病原性と抗菌ペプチドの作用機構の解明
  • 2006 - 2007 SARSコロナウイルスのヌクレオキャプシド蛋白質の構造生物学的研究
Papers (48):
  • Kohei Takeshita, Naoki Sakai, Go Ueno, Midori Horie, Hirofumi Tsujino, Mitsuhiro Arisawa, Masaki Yamamoto, Masayoshi Arai, Taku Yamashita. A large pocket structure surrounding the catalytic center in the BCG protein fromMycobacterium tuberculosis. 2024
  • Toshiyuki Waki, Riki Imaizumi, Kaichi Uno, Yamato Doi, Misato Tsunashima, Sayumi Yamada, Ryo Mameda, Shun Nakata, Taro Yanai, Kohei Takeshita, et al. Structural insights into catalytic promiscuity of chalcone synthase from Glycine max (L.) Merr.: Coenzyme A-induced alteration of product specificity. Biochemical and Biophysical Research Communications. 2024. 150080-150080
  • Riki Imaizumi, Hiroaki Matsuura, Taro Yanai, Kohei Takeshita, Shuto Misawa, Haruhiko Yamaguchi, Naoki Sakai, Yukino Miyagi-Inoue, Miki Suenaga-Hiromori, Toshiyuki Waki, et al. Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. ChemBioChem. 2024
  • Hiroaki Matsuura, Naoki Sakai, Sachiko Toma-Fukai, Norifumi Muraki, Koki Hayama, Hironari Kamikubo, Shigetoshi Aono, Yoshiaki Kawano, Masaki Yamamoto, Kunio Hirata. Elucidating polymorphs of crystal structures by intensity-based hierarchical clustering analysis of multiple diffraction data sets. Acta Crystallographica Section D Structural Biology. 2023
  • Taro Yanai, Yukino Takahashi, Eri Katsumura, Naoki Sakai, Kohei Takeshita, Riki Imaizumi, Hiroaki Matsuura, Shuntaro Hongo, Toshiyuki Waki, Seiji Takahashi, et al. Structural insights into a bacterial β-glucosidase capable of degrading sesaminol triglucoside to produce sesaminol: toward the understanding of the aglycone recognition mechanism by the C-terminal lid domain. The Journal of Biochemistry. 2023. 174. 4. 335-344
more...
MISC (6):
Education (3):
  • 2000 - 2003 Hokkaido University
  • 1998 - 2000 Hokkaido University
  • 1994 - 1998 Hokkaido University School of Science Biological Sciences
Professional career (1):
  • Master's degree (Hokkaido University, Mar. 2000), Doctor's degree (Hokkaido University, Mar. 2003) (Hokkaido University)
Work history (10):
  • 2023/04 - 現在 Japan Synchrotron Radiation Research Institute Structural Biology Division Senior scientist
  • 2022/04 - 2023/03 Japan Synchrotron Radiation Research Institute Structural Biology Division Research Scientist
  • 2018/10 - 2022/03 RIKEN RIKEN SPring-8 Center Research Scientist
  • 2018/04 - 2018/09 RIKEN Center for Biosystems Dynamics Research Research scientist
  • 2015/04 - 2018/03 RIKEN Center for Life Science Technologies Research scientist
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Committee career (1):
  • 2022/10 - 現在 The Japanese Society for Synchrotron Radiation Research Editorial committee
Association Membership(s) (3):
The Crystallographic Society of Japan ,  The Japanese Society for Synchrotron Radiation Research ,  Protein Science Society of Japan
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