Research field (4)：
Pharmaceuticals - chemistry and drug development
, Analytical chemistry
, Bioorganic chemistry
, Structural/physical organic chemistry
Research keywords (1)：
Bioorganic Chemistry
Research theme for competitive and other funds (7)：
2022 - 2025 Study on naturally-occurring peptides potentiating amphotericin B activity
2022 - 2025 トリプルネガティブ乳がん共通のバイオロジーを標的とした新規医薬品の探索
2019 - 2022 Study on cyclic peptides with amphotericin B potentiating activity
2015 - 2018 Discovery of new anti-infectives based on chemical biology
2014 - 2017 Analysis of molecular targets and development into drug discovery for cyclic peptides possessing thrombolysis-enhancing action
2011 - 2012 Development of anti-tuberculosis drugs based on calpinactam
2008 - 2010 Chemical biology aimed at the development of new thrombolytics
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Papers (54)：
Tomohisa Kanai, Tatsuya Shirahata, Shunsuke Nakamori, Rin Sato, Akito Hayashi, Yota Koizumi, Kenichiro Nagai, Susumu Ohkawara, Takayuki Hoshino, Toshiko Tanaka-Kagawa, et al. 1H-NMR-Based Biochemometric Strategy to Identify Transient Receptor Potential Vanilloid 1-Stimulating Compounds from Alpinia officinarum Rhizome. Chemical and Pharmaceutical Bulletin. 2025. 73. 3. 195-204
Reiko Seki, Kenichiro Nagai, Keisuke Kobayashi, Satoru Shigeno, Tatsuya Shirahata, Yoshinori Kobayashi, Taichi Ohshiro, Hiroshi Tomoda. Celludinone C, a new dihydroisobenzofuran isolated from Talaromyces cellulolyticus BF-0307. The Journal of antibiotics. 2024
Ryota Okamura, Katsuki Kikuchi, Akito Taniguchi, Kenichiro Nagai, Reiko Seki, Satoshi Ohte, Taichi Ohshiro, Masashi Ando, Teruyoshi Tanaka, Takashi Fukuda. The new seriniquinone glycoside by biological transformation using the deep sea-derived bacterium Bacillus licheniformis KDM612. The Journal of Antibiotics. 2024
Keisuke Kobayashi, Rio Tejima, Kenichiro Nagai, Reiko Seki, Tsuyoshi Hosoya, Yumi Une, Satoru Shigeno, Hiroshi Tomoda, Taichi Ohshiro. Paranazzamides A and B, new cyclic dipeptides containing a C7-prenylated tryptophan, produced by pathogenic reptile fungi Paranannizziopsis sp. UH-21. The Journal of antibiotics. 2024
Satoru Shigeno, Miyu Kadowaki, Kenichiro Nagai, Kanji Hosoda, Takeshi Terahara, Tomoyasu Nishimura, Naoki Hasegawa, Hiroshi Tomoda, Taichi Ohshiro. New polycyclic tetramate macrolactams with antimycobacterial activity produced by marine-derived Streptomyces sp. KKMA-0239. The Journal of Antibiotics. 2024
