Rchr
J-GLOBAL ID：200901077135246434   Update date: Mar. 24, 2024

Akari Hirofumi

アカリ ヒロフミ | Akari Hirofumi
Affiliation and department：
Kyoto University Center for the Evolutionary Origins of Human Behavior

About Kyoto University Center for the Evolutionary Origins of Human Behavior


Job title： Professor
Homepage URL  (1)： https://akari-labo.jimdo.com/
Research field  (3)： Immunology ,  Virology ,  Laboratory animal science
Research keywords  (4)： 感染症 ,  モデル動物 ,  ウイルス ,  virology
Research theme for competitive and other funds  (18)：
  • 2021 - 2023 大環状天然物の立体配座制御による高選択的な抗HIVシーズの開発
  • 2016 - 2019 Trial of CD4 positive T cell induction from iPS cells
  • 2015 - 2018 Elucidation of the onset and persistent mechanism of retrovirus induced thrombocytopenia in macaques and evaluation of their risks.
  • 2013 - 2016 Trial of generating HIV-1-susceptible rhesus monkeys by using technologies in reproductive medicine
  • 2012 - 2015 Onset and persistent mechanism of retrovirus induced thrombocytopenia in Japanese macaques.
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Papers (171)：
  • Takafumi Shichijo, Jun-Ichirou Yasunaga, Kei Sato, Kisato Nosaka, Kosuke Toyoda, Miho Watanabe, Wenyi Zhang, Yoshio Koyanagi, Edward L Murphy, Roberta L Bruhn, et al. Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 13. e2309925121
  • Jumpei Maki, Yusuke Hanaki, Ryo C Yanagita, Masayuki Kikumori, Anastasiia Kovba, Ayaka Washizaki, Chihiro Tsukano, Hirofumi Akari, Kazuhiro Irie. Biological evaluation of a phosphate ester prodrug of 10-methyl-aplog-1, a simplified analogue of aplysiatoxin, as a possible latency-reversing agent for HIV reactivation. Bioscience, Biotechnology, and Biochemistry. 2023
  • Asako Murayama, Hirofumi Akari, Takanobu Kato. Production and Purification of Cell Culture-generated Hepatitis B Virus by Transient Transfection and Density Gradient. BIO-PROTOCOL. 2023. 13. 14
  • Megumi Murata, Anastasiia Kovba, Akihisa Kaneko, Mayumi Morimoto, Akiyo Ishigami, Takayoshi Natsume, Ayaka Washizaki, Takako Miyabe-Nishiwaki, Juri Suzuki, Hirofumi Akari. Annual two-dose tetanus toxoid vaccination induces protective humoral immunity to all age groups of rhesus macaques. Experimental animals. 2023
  • Atsuhiko Hasegawa, Megumi Murata, Tomoka Fujikawa, Kuniko Katagiri, Yoshiko Nagano, Takao Masuda, Madoka Kuramitsu, Shinsuke Nakajima, Jun-Ichi Fujisawa, Kazu Okuma, et al. Vaccination with short-term-cultured autologous PBMCs efficiently activated STLV-1-specific CTLs in naturally STLV-1-infected Japanese monkeys with impaired CTL responses. PLoS pathogens. 2023. 19. 2. e1011104
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MISC (162)：
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Patents (3)：
Books (10)：
  • 感染症動物モデル-霊長類モデルを中心にー
    実験医学増刊:パンデミック時代の感染症研究 2021
  • 実験用霊長類を用いた新規HIV感染モデルの樹立
    オベリスク 2021
  • Mammarian hepaciviruses
    Atlas and textbook of pathogenic bacteria and viruses 2017 ISBN:9784832982291
  • C型肝炎ウイルスワクチンとアジュバント
    次世代アジュバント開発のためのメカニズム解明と安全性評価 2017
  • サルT細胞白血病ウイルス(simian T-cell leukemia virus: STLV)
    実験動物ニュース, 65, 30-32 2016
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Education (2)：
  • - 1993 Yamaguchi University
  • - 1988 Kagoshima University Faculty of Agriculture Veterinary Medicine
Professional career (1)：
  • (BLANK)
Work history (7)：
  • 2022/04 - 現在 Kyoto University Center for the Evolutionary Origins of Human Behavior Professor
  • 2009 - 2022/03 Primate Research Institute, Kyoto University Professor
  • 2005 - 2008 National Institutes of Biomedical Innovation, Health and Nutrition Tsukuba Primate Researh Center Laboratory chief
  • 2002 - 2004 国立感染症研究所 主任研究官
  • 1999 - 2001 NIH, NIAID (USA) Research Fellow
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Committee career (5)：
  • 2021/10 - 現在 日本エイズ学会 代議員
  • 2019 - 現在 日本獣医学会 評議員
  • 2018 - 現在 日本ウイルス学会 評議員
  • 2017 - 現在 ナショナルバイオリソースプロジェクト「ニホンザル」 運営委員
  • 2014 - 2015 日本実験動物学会 評議員
Awards (2)：
  • 2001 - The Fellows Award for Research Excellence (NIH, USA)
  • 1997 - 日本獣医学会奨励賞
Association Membership(s) (5)：
実験動物学会 ,  獣医学会 ,  エイズ学会 ,  ウイルス学会 ,  日本HTLV-1学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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