Research field (3)：
Information theory
, Biological, health, and medical informatics
, Intelligent informatics
Research keywords (7)：
Mathematical metabolic engineering
, Bioinformatics
, Algorithms
, Metabolic networks
, Genetic networks
, Boolean model
, Flux balance analysis model
Research theme for competitive and other funds (7)：
2020 - 2025 Algorithms for metabolic network design for efficient production of valuable metabolites
2019 - 2020 生産困難化合物を生成するFBAモデルの代謝ネットワークの設計
2016 - 2020 数理モデルによる生体ネットワーク制御手法の開発
2016 - 2019 Survival strategy of a cell; intra- and inter-species interaction analysis by barcode tchnology in Escherichia coli
2013 - 2016 Strategy of a cell to survive during a long term stationary phase before cell proliferation.
2013 - 2016 ブーリアンモデルによる生体ネットワークの統合的な数理モデル化と解析
2011 - 2013 ブーリアンモデルによる遺伝子制御ネットワークの解析
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Papers (84)：
Takeyuki Tamura. MetNetComp: Database for minimal and maximal gene-deletion strategies for growth-coupled production of genome-scale metabolic networks. IEEE/ACM Transactions on Computational Biology and Bioinformatics (early access version)). 2023
Takeyuki Tamura, Ai Muto-fujita, Yukako Tohsato, Tomoyuki Kosaka. Gene Deletion Algorithms for Minimum Reaction Network Design by Mixed-Integer Linear Programming for Metabolite Production in Constraint-Based Models: gDel_minRN. Journal of Computational Biology. 2023. 30. 5. 553-568
Takeyuki Tamura. Trimming gene deletion strategies for growth-coupled production in constraint-based metabolic networks: TrimGdel. IEEE/ACM transactions on computational biology and bioinformatics. 2023. 20. 2. 1540-1549
Yier Ma, Takeyuki Tamura. Dynamic Solution Space Division-Based Methods for Calculating Reaction Deletion Strategies for Constraint-Based Metabolic Networks for Substance Production: DynCubeProd. Frontiers in Bioinformatics. 2021. 1
Biological Data Mining and Its Applications in Healthcare
World Scientific 2014
Lectures and oral presentations (36)：
MetNetComp: Database for minimal and maximal gene-deletion strategies for growth-coupled production of genome-scale metabolic networks
(IIBMP2023 2023)
精密発酵のための数理代謝工学とデータベース開発
(第五回細胞農業会議 2023)
Trimming gene deletion strategies for growth-coupled production in constraint-based metabolic networks: TrimGdel
(IIBMP2022 2022)
数理代謝工学による細胞の最適化
(第四回細胞農業会議 2022)
Gene deletion algorithms for minimum reaction network design by mixed-integer linear programming for metabolite production in constraint-based models: gDel_minRN
(第10回生命医薬情報学連合大会 2021)
