Rchr
J-GLOBAL ID：200901077866493775   Update date: Feb. 01, 2024

Bonkobara Makoto

ボンコバラ マコト | Bonkobara Makoto
Affiliation and department：
Nippon Veterinary and Life Science University Faculty of Veterinary Science, School of Veterinary Medicine

About Nippon Veterinary and Life Science University Faculty of Veterinary Science, School of Veterinary Medicine


Job title： Professor
Research field  (1)： Veterinary medicine
Research keywords  (4)： Veterinary oncology ,  Veterinary clinical pathology ,  免疫学 ,  分子生物学
Research theme for competitive and other funds  (21)：
  • 2022 - 2025 Development of a novel therapeutic strategy for KIT mutation-positive canine mast cell tumor using molecular glue
  • 2019 - 2022 肥満細胞腫のチロシンキナーゼ阻害剤耐性化における多様性の解析と個別化治療の構築
  • 2018 - 2021 AIM expression, mutation and function in canine histiocytic sarcoma
  • 2015 - 2018 The role of canine AIM in histiocytic sarcoma
  • 2014 - 2017 Identification and clinical application of cancer stem cells derived from canine refractory cancers
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Papers (86)：
  • Hajime Asada, Akiyoshi Tani, Hiroki Sakuma, Miyuki Hirabayashi, Yuki Matsumoto, Kei Watanabe, Masaya Tsuboi, Shino Yoshida, Kei Harada, Takao Uchikai, et al. Whole exome and transcriptome analysis revealed the activation of ERK and Akt signaling pathway in canine histiocytic sarcoma. Scientific Reports. 2023. 13. 1
  • Masanori Kobayashi, Moe Onozawa, Shiho Watanabe, Tomokazu Nagashima, Kyoichi Tamura, Yoshiaki Kubo, Akiko Ikeda, Kazuhiko Ochiai, Masaki Michishita, Makoto Bonkobara, et al. Establishment of a BRAF V595E-mutant canine prostate cancer cell line and the antitumor effects of MEK inhibitors against canine prostate cancer. Veterinary and comparative oncology. 2023
  • Hiroyuki Tani, Ryo Miyamoto, Teruki Miyazaki, Shingo Oniki, Kyoichi Tamura, Makoto Bonkobara. A feline case of multiple myeloma treated with bortezomib. BMC veterinary research. 2022. 18. 1. 384-384
  • Hiroyuki Tani, Ryo Miyamoto, Tomokazu Nagashima, Masaki Michishita, Kyoichi Tamura, Makoto Bonkobara. Molecular characterization of canine SHP2 mutants and anti-tumour effect of SHP2 inhibitor, SHP099 , in a xenograft mouse model of canine histiocytic sarcoma. Veterinary and Comparative Oncology. 2022. 20. 1. 109-117
  • Hiroyuki Tani, Ryo Miyamoto, Syunya Noguchi, Sena Kurita, Tomokazu Nagashima, Masaki Michishita, Naoko Yayoshi, Kyoichi Tamura, Makoto Bonkobara. A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis. BMC veterinary research. 2021. 17. 1. 147-147
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MISC (15)：
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Works (2)：
  • Joint research on Keratinocyte specific secreted protein
    2001 -
  • Joint research on dendritic cell specific promoter
    2001 -
Education (2)：
  • - 1997 The University of Tokyo
  • - 1993 Nippon Veterinary and Life Science University
Professional career (1)：
  • PhD (The University of Tokyo)
Work history (6)：
  • 2015/04 - 現在 Nippon Veterinary and Life Science University
  • 2011/04 - 2015/03 Nippon Veterinary and Life Science University
  • 2005/04 - 2011/03 日本獣医畜産大学講師
  • 2000/10 - 2005/03 日本獣医畜産大学助手
  • 1998 - 2001 Research Fellow, University of Texas Southwestern Medical Center at Dallas
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Committee career (10)：
  • 2020/05 - 現在 Veterinary and Comparative Oncology Editorial Board
  • 2017 - 現在 The Veterinary Journal (London, UK) Advisory Board
  • 2014 - 現在 日本獣医学会 評議員
  • 2009 - 現在 日本小動物獣医師会 学術顧問
  • 2000 - 現在 獣医臨床病理学会 会員
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Awards (3)：
  • 2010/04 - 日本獣医生命科学大学 梅野信吉賞
  • 2001 - Albert M. Kligman Award(Society for investigative dermatology)
  • 2000 - Dermatology Foundation 2000 Research Award
Association Membership(s) (3)：
THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  JAPANESE SOCIETY OF VETERENARY CLINICAL PATHOLOGY ,  日本獣医学会
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