Rchr
J-GLOBAL ID:200901077891570741   Update date: Aug. 31, 2020

Yonehara Shin

ヨネハラ シン | Yonehara Shin
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.pharm.kyoto-u.ac.jp/Yonehara_Lab/Home_j.htm
Research field  (3): Immunology ,  Cell biology ,  Functional biochemistry
Research keywords  (7): 免疫 ,  発がん ,  発生 ,  シグナル伝達 ,  細胞死 ,  programed cell death ,  apoptosis
Research theme for competitive and other funds  (6):
  • 新しい細胞死の誘導期機構と生理機能解析
  • 細胞死シグナル分子の多様な生理機能解析
  • 発生・発がん・免疫における細胞死の解析
  • Fas抗原の媒介するアポトーシス誘導と制御機構の解析
  • Analysis of apoptosis in the immune system
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Papers (205):
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MISC (22):
  • Sakaguchi S, Kuroki S, Yonehara S. Novel types of programmed necrosis by IFN-γ in wild-type and caspase-8 KO mouse embryonic fibroblasts. The 13th International Student Seminar, Kyoto. 2015
  • A Kako, S Yonehara. Analysis of the funciton of FLASH/casp8ap2 in regulation of apoptotic and nonapoptotic cell deatrh. The 13th International Student Seminar, Kyoto. 2015
  • Yamamoto N, Fukuoka A, Ohshima N, Yonehara S. Fas-expressing natural helper cell induces hyper-production of IgE through direct interaction with B cells. Fas-expressing natural helper cell induces hyper-production of IgE through direct interaction with B cells. 2014
  • Sakaguchi S, Kuroki S, Yonehara S. Analysis of the molecular mechanism of a novel type of programmed necrosis induced by interferon-gamma/IFN-γ. The 12th International Student Seminar, Kyoto. 2014
  • Mori Y, Yonehara S. IFN-γ triggers RIP1/RIP3-mediated programmed necrosis in human and mouse monocyte-derived cell lines. The 12th International Student Seminar, Kyoto. 2014
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Patents (1):
  • 細胞増殖抑制剤及びそのスクリーニング法
Books (5):
  • Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody
    Cytokine and Growth Factor Reviews,13, 393-402 2002
  • Effects of anti-Fas antibodies on lymphocytes and other organs : Preparation of original and new monoclonal antibocties and amelioration of systemic autoimmune disease
    International Reviews of Immunology.,18/,329-345 1999
  • Discovery of Cell Surface Fas Antigen which Mediutes Apoptosis - Inducing Signals
    RINSHOKEN 20 Years pp79-85 1995
  • 細胞死を支配するFas抗原の発見
    東京都臨床医学総合研究所創立20周年記念誌 pp79-85 1995
  • 細胞死-アポプトーシス
    科学, 64/6,371-379 1994
Lectures and oral presentations  (43):
  • Caspase-8 regulates not only Fas-mediated apoptosis but also necroptosis and cell differentiation in early embryos
    (Seminar, The Research Institute for Biomedical Science and Graduate School of Biological Science 2016)
  • Specific Induction of Tumor Cell Death by Induced Knockdown of Particular Gene Expression
    (The 13th Symposium of New Frontiers Laboratories, Toray Industries, Inc 2016)
  • 細胞の死が支える生体の生と機能 ~自爆するための細胞表層レセプターの発見から多様なプログラム細胞死の解析について~
    (洛友会東京支部 秋の講演会 2015)
  • Caspase-8とRIPキナーゼが制御する細胞死と細胞分化
    (第24回日本Cell Death学会学術集会 2015)
  • 生命科学からみた老化と寿命
    (国際高等研究所「老いを考える」第6回研究会 2015)
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Education (4):
  • - 1977 Kyoto University
  • - 1977 Kyoto University
  • - 1975 Kyoto University
  • - 1975 Kyoto University
Professional career (1):
  • Doctor of Science
Work history (17):
  • 2001 - 現在 Professor, Graduated School of Biostudies, Kyoto University
  • 1994 - 現在 Professor, Institute for Virus Research, Kyoto University
  • 2001 - (平成13年)8月 1日 〜
  • 2001 - (平成13年)8月 1日 からは併任
  • 1992 - 1994 Senior Researcher, Pharmaceutical Basic Research Laboratories, JT. Inc.
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Committee career (3):
  • 1999 - 日本癌学会 評議員
  • 1996 - 日本細胞生物学会 評議員,運営委員
  • 1993 - 日本免疫学会 評議員
Awards (2):
  • 1998 - 高松宮妃癌研究基金学術賞
  • 1998 - Prize of Princess Takamatsu Cancer Research Fund (Tokyo)
Association Membership(s) (5):
日本分子生物学会 ,  日本細胞生物学会 ,  日本癌学会 ,  日本生化学会 ,  日本免疫学会
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