Rchr
J-GLOBAL ID：200901078085295346   Update date: Feb. 11, 2025

Takeuchi Hiroshi

タケウチ ヒロシ | Takeuchi Hiroshi
Affiliation and department：
Kyushu Dental College Faculty of Dental Science, Molecular & Cellular Biochemistry

About Kyushu Dental College Faculty of Dental Science, Molecular & Cellular Biochemistry


Job title： Research Associate
Homepage URL  (1)： https://www.kyu-dent.ac.jp/research/lecture/oral_pharmacological
Research field  (7)： Oral medicine (pathology) ,  Surgical dentistry ,  Oral medicine ,  Pharmacology ,  Cell biology ,  Molecular biology ,  Medical biochemistry
Research keywords  (17)： glucose metabolism ,  癌 ,  membrane traffic ,  細胞内情報伝達 ,  bone metabolism ,  osteocalcin ,  イノシトールリン脂質 ,  イノシトールリン酸 ,  GABA ,  カルシウム ,  cancer ,  Cellular Signaling ,  Calcium ,  Phosphoinositides ,  Inositol phosphates ,  Lipids ,  GABA
Research theme for competitive and other funds  (25)：
  • 2022 - 2025 Investigation of the role of GPR158 in neuropathic pain - For the development of new therapeutic strategies
  • 2018 - 2018 Safe Dental Treatment Strategies with Teriparatide for Locomotive Syndrome
  • 2018 - 2018 Elucidation of the molecular mechanism of the bone matrix protein osteocalcin in protecting brain function
  • 2017 - 2017 Investigation of the role of pancreatic alpha cells in relationship between bone and systemic metabolism.
  • 2017 - 2017 Roles of osteocalcin for energy metabolism
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Papers (76)：
  • Takahito Otani, Akiko Mizokami, Hiroshi Takeuchi, Tetsuichiro Inai, Masato Hirata. The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2024. 1871. 4. 119701-119701
  • Hikaru Fukuda, Tingting Zou, Satoshi Fujii, Shinobu Sato, Daiki Wakahara, Sen Higashi, Ting-Yuan Tseng, Ta-Chau Chang, Naomi Yada, Kou Matsuo, et al. Cyclic anthraquinone derivatives, unique G-quadruplex binders, selectively induce cancer cell apoptosis and inhibit tumor growth. PNAS nexus. 2023. 2. 7. pgad211
  • Jing Gao, Akiko Mizokami, Hiroshi Takeuchi, Aonan Li, Fei Huang, Haruki Nagano, Takashi Kanematsu, Eijiro Jimi, Masato Hirata. Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes. Journal of cell science. 2022. 135. 1
  • Hikaru Fukuda, Shinobu Sato, Tingting Zou, Sen Higashi, Osamu Takahashi, Manabu Habu, Masaaki Sasaguri, Kazuhiro Tominaga, Shigeori Takenaka, Hiroshi Takeuchi. Substituent effects of cyclic naphthalene diimide on G-quadruplex binding and the inhibition of cancer cell growth. Bioorganic & medicinal chemistry letters. 2021. 50. 128323-128323
  • Eika Ando, Sen Higashi, Akiko Mizokami, Seiji Watanabe, Masato Hirata, Hiroshi Takeuchi. Osteocalcin promotes proliferation, differentiation, and survival of PC12 cells. Biochemical and Biophysical Research Communications. 2021. 557. 174-179
ｍore...
MISC (28)：
  • 工藤 崇裕, 臼井 通彦, 東 泉, 大住 伴子, 竹内 弘, 中島 啓介. 培地グルコース濃度はAMPKを介してマクロファージの極性化に影響する. Journal of Oral Biosciences Supplement. 2018. 2018. 329-329
  • 工藤 崇裕, 臼井 通彦, 竹内 弘, 中島 啓介. マクロファージ極性化におけるグルコース濃度の影響. 日本歯周病学会会誌. 2018. 60. 春季特別. 127-127
  • 鷲尾 絢子, 吉居 慎二, 諸冨 孝彦, 竹内 弘, 北村 知昭. 各種細胞に対する新規バイオガラス配合シーラーの生体親和性. 九州歯科学会雑誌. 2017. 71. 補冊. 27-27
  • 溝上 顕子, 安河内(川久保) 友世, 竹内 弘, 平田 雅人. オステオカルシンとエネルギー代謝 (特集 骨粗鬆症治療における新しい接点). 骨粗鬆症治療 = Journal of osteoporotic medicine. 2017. 16. 1. 33-38
  • Shintaro Tsuka, Fumiko Aonuma, Sen Higashi, Tomoko Ohsumi, Ryuji Hosokawa, Masato Hirata, Hiroshi Takeuchi. Functional modulation of myotubes by osteocalcin. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2015. 128. 3. S177-S177
ｍore...
Books (1)：
  • Studies on new Ins(1,4,5)P<sub>3</sub> binding proteins with refernce to the PH domains. (共著)
    ACS Symposium Series 718 on Phosphoinositides: Chemistry, Biochemistry, and Biomedical Applications (Bruzik, K. ed.) Chapter 4, American Chemical Society 1998
Education (4)：
  • - 1998 Kyushu University
  • - 1998 Kyushu University Graduate School, Division of Dental Research
  • - 1994 Kyushu University School of Dentistry
  • - 1994 Kyushu University Faculty of Dentistry
Professional career (1)：
  • Ph.D.
Association Membership(s) (8)：
THE JAPANESE PHARMACOLOGICAL SOCIETY ,  歯科基礎医学会 ,  日本生化学会 ,  Japanese Society of Oral and Maxillofacial Surgeon ,  Japanese Association for Oral Biology ,  Japanese Biochemical Society ,  JAPANESE STOMATOLOGICAL SOCIETY ,  口腔組織培養学会
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