Eiji Sugihara

スギハラエイジ | Eiji Sugihara

Affiliation and department：
Other affiliations (1)：

University of Tsukuba

Research field (5)： Genomics , Hematology and oncology , Pathobiochemistry , Molecular biology , Tumor biology

Research keywords (7)： Animal disease model , Genome study , Tumor immunity , Cancer-related gene , Metastasis , Cancer , stem cell

Research theme for competitive and other funds (13)：

2023 - 2026 Developing a pneumoconiosis atlas at the single-cell resolution
2022 - 2025 Elucidation of the molecular basis of MYC-driven cancers and development of therapeutic strategies
2021 - 2024 Evaluation of minimal residual disease by liquid biopsy in malignant lymphoma for precise therapeutic stratification.
2022 - 2024 急性骨髄性白血病の治療抵抗性におけるMYCの役割
2020 - 2023 新規シングルセル解析法を用いたじん肺発症-進展における包括的基盤研究

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Papers (77)：

Shin Kasai, Minori Tamai, Eiji Sugihara, Naoki Oishi, Kyoko Hinata, Koshi Akahane, Kumiko Goi, Yuko Hata, Tetsuo Kondo, Takahiko Mitsui, et al. In utero tumor development and identification of CTNNB1 mutation in a newborn case of ossifying renal tumor of infancy. Pediatric blood & cancer. 2024. e30868
今枝慶蓉, 増田健太, 永井晋平, 田村友宏, 杉原英志, 山崎淳太郎, 大槻雄士, 信末博行, 千代田達幸, 小林佑介, et al. 新規マウスモデルを用いた高異型度漿液性癌の予後不良に関連するバイオマーカーの同定(Identification of biomarkers associated to poor prognosis in high-grade serous carcinoma using novel mouse models). 日本癌学会総会記事. 2023. 82回. 1044-1044
Hisako Ichihara, Manabu Yamada, Mitsuyo Kohara, Hideki Hirakawa, Andrea Ghelfi, Takuro Tamura, Akihiro Nakaya, Yasukazu Nakamura, Sachiko Shirasawa, Samatchaya Yamashita, et al. Plant GARDEN: a portal website for cross-searching between different types of genomic and genetic resources in a wide variety of plant species. BMC plant biology. 2023. 23. 1. 391-391
Atsuko Sugimoto, Takahiro Watanabe, Kazuhiro Matsuoka, Yusuke Okuno, Yusuke Yanagi, Yohei Narita, Seiyo Mabuchi, Hiroyuki Nobusue, Eiji Sugihara, Masaya Hirayama, et al. Growth Transformation of B Cells by Epstein-Barr Virus Requires IMPDH2 Induction and Nucleolar Hypertrophy. Microbiology spectrum. 2023. e0044023
Tasuku Mariya, Yui Shichiri, Takeshi Sugimoto, Rie Kawamura, Syunsuke Miyai, Hidehito Inagaki, Eiji Sugihara, Keiko Ikeda, Tsuyoshi Baba, Aki Ishikawa, et al. Clinical application of long-read nanopore sequencing in a preimplantation genetic testing pre-clinical workup to identify the junction for complex Xq chromosome rearrangement-related disease. Prenatal diagnosis. 2023. 43. 3. 304-313

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MISC (18)：

竹内章人, 武東義成, 吉村文, 渡辺崇, 柳久乃, 杉原英志, 全並賢二, 佐谷秀行, 白木良一, 住友誠. グルタミノリシスを標的とした新規腎細胞癌治療の検討(Targeting glutamine addiction with potent drug combination therapy for renal cell carcinoma). 日本癌学会総会記事. 2023. 82回. 1062-1062
大場茂生, 杉原英志, 山田勢至, 中江俊介, 西山悠也, 武藤淳, 安達一英, 安部雅人, 佐谷秀行, 廣瀬雄一. がんゲノム診断がん遺伝子パネル検査を用いた髄膜腫の解析. Brain Tumor Pathology. 2023. 40. Suppl. 061-061
佐谷秀行, 杉原英志. 【泌尿器科医必見!がんゲノム医療の基本と応用】本邦におけるがん遺伝子パネル検査の現状. 泌尿器外科. 2023. 36. 3. 197-200
糠谷拓尚, 住友誠, 竹田真由, 杉原英志, 佐谷秀行, 白木良一. 前立腺がん-リスク別・進行期別治療のトピックス- 前立腺癌のBRCA遺伝子のloss of heterozygosityの頻度とその意義. 日本癌治療学会学術集会抄録集. 2022. 60回. OWS18-6
信末博行, 清水孝恒, 高橋信博, 山口さやか, 杉原英志, 大西伸幸, 佐谷秀行. MKL1の阻害は化学療法抵抗性骨肉腫細胞において抗がん剤の抗腫瘍効果を増強する(Inhibition of MKL1 enhances the effects of anticancer drugs in chemoresistant osteosarcoma cells). 日本癌学会総会記事. 2022. 81回. J-1026

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Patents (1)：

14-3-3タンパク質活性調節剤

Books (1)：

がんゲノム医療結果報告書の読み方と患者への伝え方 : エキスパートパネルの実際
医学と看護社 2020 ISBN:9784909888105

Lectures and oral presentations (78)：

マウス卵管上皮オルガノイドを用いた新規卵巣癌マウスモデルの開発(Development of a new ovarian cancer mouse model by engineering mouse fallopian tube epithelial organoids)
(日本癌学会総会記事 2022)
当院における院内がんゲノム検査の運用と課題
(医療検査と自動化 2022)
Improvement of a plant genome information portal site, Plant GARDEN (2021・Q4 ver)
(育種学研究 2022)
植物ゲノム情報ポータルサイト「Plant GARDEN」の改訂(2021年度・第2四半期版)
(トーゴーの日2021 2021)
全ゲノム解析による常染色体優性多発性嚢胞腎(ADPKD)遺伝子変異の検討
(日本腎臓学会誌 2021)

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Education (3)：

2003 - 2006 University of Tsukuba Comprehensive Human Sciences
2001 - 2003 University of Tsukuba Medical Sicence
1997 - 2001 Rikkyo University Faculty of Science Department of Life Science

Professional career (2)：

M.S. in medical sicence (University of Tsukuba)
Ph.D. in medicine (University of Tsukuba)

Work history (9)：

2022/01 - 現在 Fujita Health University Associate Professor
2021/03 - 現在 University of Tsukuba R & D Center for Precision Medicine Visiting associate professor
2021/01 - 2021/12 Fujita Health University Center for Joint Research Facilities Support, Research Promotion and Support Headquaters Associate Professor
2019/04 - 2020/12 University of Tsukuba Reaerch and Development Center for Precision Medicine Associate Professor
2017/04 - 2019/03 The University of Tsukuba Reaerch and Development Center for Precision Medicine Assistant professor

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Committee career (1)：

2023/01 - 現在 Japanese Cancer Association Councilor

Awards (9)：

2022/08 - 公益財団法人武田科学振興財団医学系研究助成
2021/08 - 公益財団法人愛知県がん研究振興会第46回(2021年度)がんその他の悪性新生物研究助成金
2017 - Japanese Society of Hematology Research grant in 2017
2017 - 公益信託白血病研究基金一般研究賞受賞
2017 - 公益財団法人がんの子どもを守る会研究助成金受賞

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Association Membership(s) (5)：

The American Society of Hematology , American Assciation of Cancer Research , THE JAPANESE SOCIETY OF HEMATOLOGY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE CANCER ASSOCIATION

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