Rchr
J-GLOBAL ID：200901078327050475
Update date: Sep. 08, 2022
Okano Yukio
オカノ ユキオ | Okano Yukio
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Affiliation and department：
The Open University of Japan Graduate School of Medicine
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Detailed information
Job title：
Professor
Research field (2)：
Pathobiochemistry
, Medical biochemistry
Research keywords (5)：
RING-finger
, Aurora kinase
, 分子病態
, Cellular Signal transduction
, Molecular Pathobiochemistry
Research theme for competitive and other funds (4)：
1995 - ユビキチン化を介した細胞機能の分子機構
1995 - 細胞増殖の分子病態学
1995 - Molecular mechanisms of cellular functions mediated via ubiquitination
1995 - molecular pathobiochemistry of cell proliferation
Papers (31)：
Katsuya Sato, Masashi Kimura, Kazue Sugiyama, Masashi Nishikawa, Yukio Okano, Hitoshi Nagaoka, Takahiro Nagase, Yukio Kitade, Hiroshi Ueda. Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY. 2016. 291. 48. 25227-25238
Takahiro Yamauchi, Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Junji Kawaguchi, Yumi Nishii, Takashi Yoshioka, Yukio Okano, Yoshinobu Hirose, Osamu Kozawa, et al. UVC Radiation Induces Downregulation of EGF Receptor via Phosphorylation at Serine 1046/1047 in Human Pancreatic Cancer Cells. RADIATION RESEARCH. 2011. 176. 5. 565-574
Rie Matsushima-Nishiwaki, Seiji Adachi, Takashi Yoshioka, Eisuke Yasuda, Yasumasa Yamagishi, Junya Matsuura, Masato Muko, Rutsu Iwamura, Takahiro Noda, Hidenori Toyoda, et al. Suppression by Heat Shock Protein 20 of Hepatocellular Carcinoma Cell Proliferation via Inhibition of the Mitogen-Activated Protein Kinases and AKT Pathways. JOURNAL OF CELLULAR BIOCHEMISTRY. 2011. 112. 11. 3430-3439
Sach Kozawa, Ayako Honda, Naomi Kajiwara, Yasuhiko Takemoto, Tomoko Nagase, Hideki Nikami, Yukio Okano, Shigeru Nakashima, Nobuyuki Shimozawa. Induction of peroxisomal lipid metabolism in mice fed a high-fat diet. MOLECULAR MEDICINE REPORTS. 2011. 4. 6. 1157-1162
Miki Matsunami, Takashi Yoshioka, Tokiko Minoura, Yukio Okano, Yoshinori Muto. Evolutionary Features and Intracellular Behavior of the PRTB Protein. BIOCHEMICAL GENETICS. 2011. 49. 7-8. 458-473
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MISC (112)：
Seiji Baba, Akira Hara, Keizo Kato, Nguyen Khanh Long, Yuichiro Hatano, Masashi Kimura, Yukio Okano, Yasuhiro Yamada, Toshiyuki Shibata. Aberrant promoter hypermethylation of the CHFR gene in oral squamous cell carcinomas. ONCOLOGY REPORTS. 2009. 22. 5. 1173-1179
Yukie Matsuyama, Tomoya Hayashi, Hiroyuki Terawaki, Tsuneo Negawa, Tomoyoshi Terada, Yukio Okano, Seiichi Era. Human astrocytes and aortic endothelial cells actively convert the oxidized form of albumin to the reduced form: reduced albumin might participate in redox regulation of nerve and blood vessel systems. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009. 59. 3. 207-215
Satoshi Nemoto, Mitsuhiro Nakamura, Yosuke Osawa, Saki Kono, Yoshinori Itoh, Yukio Okano, Takashi Murate, Akira Hara, Hiroshi Ueda, Yoshinori Nozawa, et al. Sphingosine Kinase Isoforms Regulate Oxaliplatin Sensitivity of Human Colon Cancer Cells through Ceramide Accumulation and Akt Activation. JOURNAL OF BIOLOGICAL CHEMISTRY. 2009. 284. 16. 10422-10432
Kazuhiko Wakahara, Takatoshi Ohno, Masashi Kimura, Takahiro Masuda, Satoshi Nozawa, Taikoh Dohjima, Takatoshi Yamamoto, Akihito Nagano, Gou Kawai, Aya Matsuhashi, et al. EWS-Fli1 Up-Regulates Expression of the Aurora A and Aurora B Kinases. MOLECULAR CANCER RESEARCH. 2008. 6. 12. 1937-1945
Yoshiko Banno, Satoshi Nemoto, Masashi Murakani, Masashi Kimura, Yoshihito Ueno, Kenji Ohguchi, Akira Hara, Yukio Okano, Yukio Kitade, Minoru Onozuka, et al. Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway. JOURNAL OF NEUROCHEMISTRY. 2008. 104. 5. 1372-1386
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Books (6)：
細胞内シグナル伝達機構(共著)
図説分子病態学 1995
Intracellular signal transduction system
1995
K-rasでトランスフォ-ムした線維芽細胞のホスフアチジルコリン分解におけるブラジキニンによるCa<sup>2+</sup>オシレ-ションの関与
1992
Involvement of bradykinin-induced [Ca<sup>2+</sup>]i oscillations in phosphatidylcholine breakdown in K-ras-transformed fibroblasts (共著)
Recent Progress on Kinins 1992
膜透過性細胞の調製法(共著)
新生化学実験講座東京化学同人 1990
ｍore...
Works (4)：
中心体キナーゼの機能解析
1996 - 2001
Functional Analysis of Centrosomal Kinase
1996 - 2001
ユビキチン化の分子機構
1998 -
Molecular mechanisms of ubiquitination
1998 -
Education (4)：
- 1980 Gifu University
- 1980 Gifu University Graduate School, Division of Medicine
- 1976 Gifu University School of Medicine Medical Course
- 1976 Gifu University Faculty of Medicine
Professional career (2)：
MD (Gifu University)
PhD (Gifu University Graduate School of Medicine)
Work history (7)：
2013/04 - 現在 Open University of Japan Gifu Study Center Director
2010/04 - 2013/03 Gifu University Trustee and Vice President
2004/04 - 2010/03 Gifu University Graduate School of Medicine
1993/07 - 2004/03 - 岐阜大学 教授(医学部分子病態学)
1991 - 1993 岐阜大学 助教授(医学部生化学)
1986 - 1991 岐阜大学 講師(医学部生化学)
1985 - 1986 岐阜大学 助手(医学部生化学)
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Committee career (1)：
日本生化学会 評議員
Association Membership(s) (5)：
日本脂質生化学研究会
, 日本分子生物学会
, 日本癌学会
, 日本生化学会
, 日本生化学会
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