Arano Yasushi

• 2001 - 2007 細胞内酸化還元状態の画像解析を目的とする放射性医薬品の設計
• 2001 - 2007 Chemical design of radiopharmaceuticals for determining intracellular redox changes
• 1999 - 2007 脳内コリンエステラーゼ活性の画像解析薬剤の開発
• 1999 - 2007 Design, synthesis and biological evaluation of radiopharmaceuticals for estimating choline esterase activities in the brain
• 2000 - 2005 センチネルリンパ節の画像診断に有用な放射性医薬品の開発
2000 - 2005 Development of radiopharmaceuticals for diagnosis of sentinel lymph nodes
1999 - 2005 放射線治療の早期効果判定に有用な放射性医薬品の新規開発
1999 - 2005 癌の核医学画像診断,内用放射線治療に有用なペプチド,ポリペプチドのラジオアイソトープ標識薬剤の新規開発
1999 - 2005 Development of radiopharmaceuticals for early diagnosis of radiotherapy of tumor
1998 - 2005 高分子医薬品の生体内挙動の追跡薬剤の開発
1998 - 2005 Chemical design of radiolabeling agents for protein pharmacokinetics
1995 - 2005 Molecular design, synthesis and biological evaluation of radiolabeling agents for targeted imaging and radiotherapy of tumor.
1998 - 2004 癌の疼痛緩和を目的とする放射性医薬品の設計
1998 - 2004 Chemical design of radiopharamceuticals for the treatment of painful osseous metastases

• NAKAYAMA M, HARATAKE M, ONO M, KOISO T, HARADA K, NAKAYAMA H, YAHARA S, OHMOMO Y, ARANO Y. A new 68Ge-68Ga generator system using organic polymer containing N-methylglucamine groups for absorbent of 68Ge. Applied Radiat. Isot. 2003. 58. 1. 9-14
• A new 68Ge-68Ga generator system using organic polymer containing N-methylglucamine groups for absorbent of 68Ge. Applied Radiat. Isot. 2003. 58 (1), 9-14
• M Ono, Y Arano, T Mukai, T Saga, Y Fujioka, K Ogawa, H Kawashima, J Konishi, H Saji. Control of radioactivity pharmacokinetics of Tc-99m-HYNIC-labeled polypeptides derivatized with ternary ligand complexes. BIOCONJUGATE CHEMISTRY. 2002. 13. 3. 491-501
• 94. Separation of 68Ga from 68Ge using macroporous organic polymer containing N-methyglucamine groups. Anal. Chim. Acta. 2002. 453, 135-141
• A Laznickova, M Laznicek, F Trejtnar, L Melicharova, KH Suzuki, H Akizawa, Y Arano, A Yokoyama. Distribution and elimination characteristics of In-111-DTPA-D-Phe(1)-octreotide and In-111-DTPA-L-Phe(1)-octreotide in rats. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 2002. 27. 1. 37-43

ｍore...

• 2-Oxopropionaldehydebis(thiosemicarbazone) derivatives.
• Radioactive diagnostic agent.
• Glucosone bis(thiosemicarbazone) complexes as radioactive diagnostic agents.
• Phenylpropane-1,2-dione bis(thiosemicarbazone) derivatives.
• Fatty acid derivative labelled with a radioactive transition metal.

ｍore...

• Conjugation Chemistries to Reduce Renal Radioactivity Levels of Antibody Fragments.
  Biomedical Polymers and Polymer Therapeutics (E. Chiellini, J. Sunamoto, C. Migliaresi, R. M. Ottenbrite, D. Cohn Eds.) Kluwer Academic/Plenum Publishers, New York, U.S.A. 2001
• Conjugation Chemistries to Reduce Renal Radioactivity Levels of Antibody Fragments.
  Biomedical Polymers and Polymer Therapeutics (E. Chiellini, J. Sunamoto, C. Migliaresi, R. M. Ottenbrite, D. Cohn Eds.) Kluwer Academic/Plenum Publishers, New York, U.S.A. 2001
• Intracellular Metabolism of 99mTc-Labeled Polypeptides using Hydrazino Nicotinamide (HYNIC) as a Chelating Agent.
  Technetium in Chemistry and Nuclear Medicine (Nicolini M.and Mazzi U. eds.) Edizion Minerva Medica, Corso Bramante, Italy, 1999
• Intracellular Metabolism of 99mTc-Labeled Polypeptides using Hydrazino Nicotinamide (HYNIC) as a Chelating Agent.
  Technetium in Chemistry and Nuclear Medicine (Nicolini M.and Mazzi U. eds.) Edizion Minerva Medica, Corso Bramante, Italy 1999
• A Chemical Strategy to Reduce Renal Radioactivity Levels of Antibody Fragments.
  Synthesis and Applications of Isotopically Labelled Compounds 1997. R.L. Heys and D.G. Melillo eds. John Wiley & Sons, Chichester, UK. 1998

ｍore...

• - 1982 Kyoto University
• - 1982 Kyoto University Graduate School, Division of Pharmaceutical Sciences
• - 1977 Kyoto University Faculty of Pharmaceutical Sciences
• - 1977 Kyoto University Faculty of Pharmaceutical Science

• Bifunctional Chelating Agents for Tc-99m-Labeling of Proteins

• 1992 - 日本核医学会賞
• 1992 - Japanses Society of Nuclear Medicine Award
• 1982 - 世界核医学会賞
• 1982 - Amasham Prize (The 3rd World Congress of Nuclear Medicine and Biology)

International Society of Radiopharmaceutical Chemistry and Biology ,  日本DDS学会 ,  米国核医学会 ,  日本核医学会 ,  日本薬学会 ,  International Society of Radiopharmaceutical Chemistry and Biology ,  Society of Nuclear Medicine ,  Japan Society of Drug Delivery System ,  Japanese Society of Nuclear Medicine ,  Japanese Society of Pharmaceutical Sciences