Rchr
J-GLOBAL ID：200901079415004978   Update date: Oct. 31, 2024

Kukita Yoji

クキタ ヨウジ | Kukita Yoji
Affiliation and department：
大阪国際がんセンター 研究所

About 大阪国際がんセンター 研究所


Job title： 主任研究員
Research field  (2)： Tumor diagnostics and therapeutics ,  Genomics
Research theme for competitive and other funds  (12)：
  • 2022 - 2025 エピゲノム解析による新規疾患分類候補肉腫の発生・増殖機序の解明
  • 2022 - 2025 消化管上皮の発生・分化原理の理解に基づく化生発症メカニズムの解明
  • 2016 - 2018 Development of analytical system for cell-free DNA in plasma using high-fidelity DNA sequencing and absolute quantitation
  • 2013 - 2016 Identification of causative genes for hereditary cancer by genome analyses of familial cancer cases and its application
  • 2012 - 2014 Elucidation of structural variations in Japanese genome by massively parallel sequencing of haploid genome
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Papers (77)：
  • Harumi Nakamura, Yoji Kukita, Hironari Tamiya, Satoshi Takenaka, Toshinari Yagi. Thoracic small round cell sarcoma with FGFR2::DCTN2 fusion. Histopathology. 2024
  • Harumi Nakamura, Yoji Kukita, Ken-ichi Yoshida, Satoshi Takenaka, Toshinari Yagi. Aggressive undifferentiated small round cell sarcoma of the thorax showing TOP2B::UBA3 fusion. Histopathology. 2024
  • Masamune Masuda, Keita Iida, Sadahiro Iwabuchi, Mie Tanaka, Satoshi Kubota, Hiroyuki Uematsu, Kunishige Onuma, Yoji Kukita, Kikuya Kato, Shoji Kamiura, et al. Clonal Origin and Lineage Ambiguity in Mixed Neuroendocrine Carcinoma of the Uterine Cervix. The American journal of pathology. 2023
  • Ken-ichi Yoshida, Yoji Kukita, Harumi Nakamura, Toru Wakamatsu, Keiichiro Honma, Toshinari Yagi. A case of spindle cell rhabdomyosarcoma with a ZFP64::NCOA3 fusion. Genes, Chromosomes and Cancer. 2023
  • Yoji Kukita, Kei Kunimasa, Takashi Akazawa, Yu Mizote, Hideaki Tahara. A Method for Extending Target Regions of Genomic Profiling by Combining a Custom Probe Pool with a Commercial Targeted Panel. The Journal of Applied Laboratory Medicine. 2023. 8. 6. 1065-1073
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MISC (31)：
  • 國政 啓, 河内 勇人, 中村 ハルミ, 久木田 洋児, 本間 圭一郎, 大阪国際がんセンター/病理ゲノムユニット. ABCP療法が奏効したSMARCA4-DTS or DTSTの3症例. 日本病理学会会誌. 2021. 110. 1. 290-290
  • 遠藤 洋子, 奥山 裕照, 久保田 哲, 久木田 洋児, 井上 正宏. 患者腫瘍移植モデルとex vivo培養間のシャトルシステムによる臨床効果評価技術の確立. 日本癌学会総会記事. 2016. 75回. P-3297
  • Junji Uchida, Kikuya Kato, Yoji Kukita, Toru Kumagai, Kazumi Nishino, Haruko Daga, Izumi Nagatomo, Shigeyuki Oba, Yuri Ito, Koji Takeda, et al. Genotyping and monitoring of circulating tumor DNA in lung cancer patients during the early period of EGFR-TKI treatment using deep sequencing. JOURNAL OF CLINICAL ONCOLOGY. 2015. 33. 15
  • 鐘本 学, 白畑 充章, 谷口 一也, 久木田 洋児, 荒川 芳輝, 宮本 享, 加藤 菊也. 次世代シークエンサーによるglioblastoma患者のMGMT promotor領域のメチル化の定量的評価(The quantitative assessment of MGMT promotor methylation of glioblastoma patients by the next generation sequencer). 日本癌学会総会記事. 2012. 71回. 522-522
  • 鐘本 学, 白畑 充章, 荒川 芳輝, 谷口 一也, 久木田 洋児, 加藤 菊也, 宮本 享. 次世代シークエンサーを用いたMGMT遺伝子のpromoter methylationの評価の試み. Brain Tumor Pathology. 2012. 29. Suppl. 188-188
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Patents (1)：
  • 核酸分子数計測法
Books (8)：
  • リキッドバイオプシー-体液中腫瘍マーカーの検出・解析技術-
    シーエムシー出版 2017 ISBN:9784781312590
  • 遺伝子医学MOOK オミックスで加速するがんバイオマーカー研究の最新動向
    メディカルドゥ 2015
  • DNAチップ/マイクロアレイ臨床応用の実際
    メディカルドゥ 2008
  • Methods in Molecular Biology. Single Nucleotide Polymorphisms: Methods and Protocols
    Springer 2006 ISBN:9781603274104
  • Methods in Molecular Biology. Single Nucleotide Polymorphisms: Methods and Protocols
    Humana Press Inc. 2003 ISBN:9781592593279
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Lectures and oral presentations  (11)：
  • Effective detection of fusion gene variants using targeted RNA sequencing in rare tumors
    (2021)
  • Quantitative detection of ALK fusions in plasma DNA from lung cancer patients using adapter PCR-based target sequencing
    (2019)
  • Selective detection of somatic mutations in circulating tumor DNA from pancreatic cancer patients by next-generation sequencing and a bioinformatic variant filter
    (Human Genome Meeting 2018 2018)
  • Selective detection of somatic mutations in circulating tumor DNA from cancer patients
    (The 76th Annual Meeting of the Japanese Cancer Association 2017)
  • DNA分子高精度配列決定及び絶対定量による血中遊離DNA中の突然変異検出
    (NGS現場の会血液核酸マーカー分科会‎第2回研究会 2016)
ｍore...
Education (3)：
  • 1997 - 2000 Kyushu University Faculty of Medical Science Department of Molecular Biology
  • 1995 - 1997 Kyushu University Faculty of Science Department of Biology
  • 1991 - 1995 Kyushu University Faculty of Science Department of Biology
Professional career (2)：
  • Ph.D. (Kyushu University)
  • 修士(理学) (九州大学)
Work history (8)：
  • 2020/04 - 現在 Osaka International Cancer Institute Research Center
  • 2017/04 - 2020/03 Nara Institute of Science and Technology Associate Professor
  • 2009/04 - 2017/03 Osaka Medical Center for Cancer and Cariovascular Diseases Researcher
  • 2004/08 - 2009/03 Kyushu University Assistant Professor
  • 2003/11 - 2004/07 Kyushu University Assictant Professor
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Association Membership(s) (2)：
日本癌学会 ,  日本分子生物学会
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