Hamano Yoshimitsu

ハマノヨシミツ | Hamano Yoshimitsu

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://applied-microbiology-fpu.com

Research field (2)： Applied microbiology , Bioorganic chemistry

Research keywords (6)：生合成 , 二次代謝産物 , 放線菌 , Biosynthesis , Secondary metabolites , Actinomycetes

Research theme for competitive and other funds (18)：

2022 - 2027 Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.
2022 - 2024 天然PIECE抱合法による生理活性ペプチドの消化管吸収への挑戦
2020 - 2023 Bacterial CPP-mediated internalization of antibodies and proteins
2020 - 2022 New drug modalities with hydrophilic mid-size peptides from microorganisms
2018 - 2022 Dissecting reaction mechanisms of novel peptide epimerases

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Papers (74)：

Hajime Katano, Mami Maruyama, Kohei Uematsu, Chitose Maruyama, Yoshimitsu Hamano. Separation of an ε-poly-L-lysine derivative by solvent extraction under a controlled interfacial potential difference. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2023
Hiroki Sakae, Yamato Takeuchi, Chitose Maruyama, Yoshimitsu Hamano, Hirohisa Nagatani. Phase transfer mechanisms of fluorophore-labeled cell-penetrating peptide ε-poly-l-α-lysine at liquid|liquid interfaces. Electrochimica Acta. 2023. 462. 142769-142769
Wanlu Xiao, Takeshi Tsunoda, Chitose Maruyama, Yoshimitsu Hamano, Yasushi Ogasawara, Tohru Dairi. Peptide epimerase-dehydratase complex responsible for biosynthesis of the linaridin class ribosomal peptides. Bioscience, biotechnology, and biochemistry. 2023. 87. 11. 1316-1322
Fumihito Hasebe, Kazuya Adachi, Kazuya Yamanaka, Tadao Oikawa, Chitose Maruyama, Yoshimitsu Hamano. Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-L-lysine production in Streptomyces albulus. The Journal of antibiotics. 2023. 76. 9. 522-531
Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo, Kuan-Hung Lin, Chun-Liang Chen, Chi-Fon Chang, Zhe-Chong Wang, Yasushi Ogasawara, Tohru Dairi, et al. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nature communications. 2023. 14. 1. 2528-2528

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MISC (81)：

鈴木海渡, 小倉知也, 武内大和, 丸山千登勢, 濱野吉十. Cell penetration and bioactivity of peptides natural products modified with polycationic isopeptides. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
岸千紘, 丸山千登勢, 山中一也, 五十嵐雅之, 濱野吉十. 抗生物質resormycin生合成遺伝子群に見出したPhenylalanine水酸化酵素の機能解析. 日本放線菌学会大会講演要旨集. 2021. 35th (CD-ROM)
武内大和, 牛丸和乗, 兼田康平, 丸山千登勢, 濱野吉十. 微生物由来ポリカチオンペプチドを利用したタンパク質の細胞内送達法の開発. 日本生化学会大会(Web). 2021. 94th
鈴木海渡, 小倉知也, 武内大和, 兼田康平, 丸山千登勢, 濱野吉十. ポリカチオン修飾した抗生物質バシトラシンの細胞膜透過性と生理活性の評価. 日本生化学会大会(Web). 2021. 94th
中嶋優, HAMDY Sherif A. M. A., 内山駿, 丸山千登勢, 濱野吉十, 森田洋行. X線結晶構造解析に基づく抗生物質glycylthricin生合成酵素に見られる基質特異性の解明. 日本薬学会北陸支部例会/日本病院薬剤師会北陸ブロック学術大会プログラム集&要旨集(Web). 2021

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Education (3)：

Professional career (1)：

Work history (7)：

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Committee career (11)：

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Awards (10)：

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Association Membership(s) (4)：

Japanese Society of Enzyme Engineering , The Society for Biotechnology, Japan , SOCIETY FOR ACTINOMYCETES JAPAN , 日本農芸化学会

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