Kaneko Shin

カネコシン | Kaneko Shin

Affiliation and department：
Job title： Professor
Other affiliations (1)：

University of Tsukuba Faculty of Medicine Professor

Homepage URL (1)： http://www.cira.kyoto-u.ac.jp/j/index.html

Research field (3)： Hematology and oncology , Immunology , Cell biology

Research keywords (27)：骨髄増殖性疾患 , 癌幹細胞生物学 , STAT5A , レトロウイルスベクター , 疾患モデルマウス , 原発性骨髄線維症 , 造血幹細胞 , c-Myc , 真性多血症 , STAT5 , 血液腫瘍学 , JAK2V617F変異 , 疾患モデル動物 , 骨髄増殖性腫瘍 , 間葉系幹細胞 , 胞体突起形成 , 血小板産生 , 巨核球 , 情報伝達系 , 細胞療法 , 幹細胞生物学 , 遺伝子治療 , 血液学 , Stem cell biology , Clinical Hematology , Cell Therapy , Gene Therapy

Research theme for competitive and other funds (22)：

2022 - 2026 The Shape of Human Life Explored in Science and Science Fiction
2022 - 2026 胸腺内細胞相互干渉の高解像度時間空間的解析による人工リンパ球造血メカニズムの解明
2020 - 2021 Development of a 3D tumor-on-a-chip platform for cancer immunotherapy
2018 - 2021 The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells
2017 - 2020 Development of patient-derived cancer on-a-chip devices for cancer immunotherapy

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Papers (81)：

Hisashi Yano, Keiko Koga, Takayuki Sato, Tokuyuki Shinohara, Shoichi Iriguchi, Atsushi Matsuda, Kazuki Nakazono, Maki Shioiri, Yasuyuki Miyake, Yoshiaki Kassai, et al. Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model. Cell stem cell. 2024. 31. 6. 795-802
Shin-Ichiro Takayanagi, Sayaka Chuganji, Masahiro Tanaka, Bo Wang, Saki Hasegawa, Ken Fukumoto, Nariaki Wasano, Makoto Kakitani, Nakaba Ochiai, Yohei Kawai, et al. A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism. Communications biology. 2024. 7. 1. 685-685
張静, 王博, 蟹江慶太郎, 吉田宗弘, 金子新. Downregulating the immune synapses of iPSC-derived T cells to escape the NK cell-mediated killing(タイトル和訳中). 日本がん免疫学会総会・日本バイオセラピィ学会学術集会総会合同大会プログラム・抄録集. 2024. 28回・37回. 127-127
Sota Kurihara, Akihiro Ishikawa, Shin Kaneko. Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy. Inflammation and regeneration. 2024. 44. 1. 20-20
Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Derin B Keskin, Kenneth Livak, Shuqiang Li, Mubin Tarannum, Rizwan Romee, et al. Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ+ T cells targeting multiple myeloma. Blood. 2024. 143. 10. 895-911

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MISC (132)：

泉響介, 石川晃大, 金子新. Frontiers of universal CAR-T/NK cells using genome-edited iPS cells. 医学のあゆみ. 2024. 288. 3
蟹江慶太郎, 金子新, 金子新. ex vivo gene editing-HLA editing for regenerative immunotherapy. 実験医学. 2024. 42. 6
Keitaro Kanie, Shin Kaneko. [Basic Research and Clinical Development of Regenerative Immunotherapy Using iPS Cells]. Gan to kagaku ryoho. Cancer & chemotherapy. 2023. 50. 5. 571-576
早稲田真澄, 金子新. 人工胸腺オルガノイドからのCAR-T細胞の分化. 実験医学・増刊. 2023. 41. 2. 101-106
金子新, 金子新. 遺伝子治療 7.遺伝子改変T細胞療法ゲノム編集技術を応用した遺伝子改変T細胞療法. 日本医師会雑誌. 2023. 152

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Lectures and oral presentations (171)：

Development of iPSC-derived CAR-T and CAR-NK cell therapy
(2024)
iPS細胞技術を用いた免疫細胞治療の開発
(シンポジウム:細胞治療薬開発研究におけるin vivo 実験モデルの果たす役割 2024)
iPSC-derived cells
(3rd Translational Research Conference: Immune & Cellular Therapies 2024)
iPS細胞を使った最先端のがん治療研究~万能細胞で挑む免疫治療~
(海上自衛隊舞鶴地方総監部主催特別講演会 2024)
だれも取り残さない免疫治療を求めて
(第16回日本血液疾患免疫療法学会学術集会 2024)

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Education (3)：

1998 - 2002 Tsukuba University Graduate School of Medicine Hematology/Immunology
1997 - 1998 Ehime University
1989 - 1995 Tsukuba University School of Medicine

Professional career (1)：

Doctor(Medicine) (University of Tsukuba)

Work history (13)：

2020/12 - 現在 Kyoto University Center for iPS Cell Research and Application, Professor
2020/08 - 現在 University of Tsukuba Faculty of Medicine Professor
2022/04 - 2024/03 Kyoto University Center for iPS Cell Research and Application Dupty Director
2012/10 - 2020/11 Kyoto University Center for iPS Cell Research and Application Associate Professor
2009/10 - 2012/09 Tokyo University Center for Stem Cell Biology and Regenerative Medicine Assistant Professor

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Committee career (19)：

2023/04 - 現在日本再生医療学会選奨委員
2023/04 - 現在日本再生医療学会理事
2021/10 - 現在日本再生医療学会国際委員
2021/10 - 現在日本免疫治療学会監事
2021/04 - 現在京都大学iPS細胞研究所動物実験委員会委員長

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Awards (5)：

2023/01 - 京都大学iPS細胞研究所第10回CiRA賞
2014/01 - 京都大学iPS細胞研究所第1回CiRA賞
2012/06 - 日本再生医療学会 Johnson & Johnson Innnovation award
2010/07 - 日本遺伝子治療学会 JGM award 若手研究者奨励賞
2001/09 - 平成14年度日本血液学会奨励賞

Association Membership(s) (10)：

Japanese society of gene and cell therapy , Japanese Society for Transplantation and Cellular Therapy , Japanese society of internal medicine , Japanese society of hematology , Japanese Society of Immunotherapy for Hematological Disorders , Japan Research Association for Immunotherapeutics , Japanese Association of Cancer Immunology , THE JAPANESE SOCIETY FOR IMMUNOLOGY , THE JAPANESE CANCER ASSOCIATION , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE

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