Rchr
J-GLOBAL ID:200901079918898178   Update date: Jan. 30, 2024

Iwabuchi Kazuhisa

イワブチ カズヒサ | Iwabuchi Kazuhisa
Affiliation and department:
Job title: Specially Appointed Professor
Other affiliations (2):
Homepage URL  (2): http://www.juntendo.ac.jp/graduate/laboratory/labo/kankyo_igaku/index.htmlhttp://www.juntendo.ac.jp/graduate/nurs/research/profile_12.html
Research field  (4): Immunology ,  Medical biochemistry ,  Cell biology ,  Structural biochemistry
Research keywords  (7): 糖鎖生物学 ,  細胞生物学 ,  免疫学 ,  生化学 ,  Cell Biology ,  Immunology ,  Biochemistry
Research theme for competitive and other funds  (24):
  • 2023 - 2026 Crosstalk between purinergic signaling and the complement system in sepsis-induced immunosuppression.
  • 2019 - 2022 Excessive complement activation in multiple organ dysfunciton
  • 2016 - 2020 Mechanisms of liver regeneration mediated by sinusoidal microcirculation in the regulation of autotaxin and lysophospholipid
  • 2015 - 2018 Palmitic acid elicits insulin resistance and oxidative cell injury through clusterization of lipid rafts in murine hepatocytes.
  • 2015 - 2017 Development of glycosylated lipid metabolomics system for clarifying their neuronal function
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Papers (111):
  • Ryosuke Shimai, Kei Hanafusa, Hitoshi Nakayama, Eriko Oshima, Masaki Kato, Koki Kano, Ichiro Matsuo, Tetsuro Miyazaki, Takashi Tokano, Yoshio Hirabayashi, et al. Lysophosphatidylglucoside/GPR55 signaling promotes foam cell formation in human M2c macrophages. Scientific reports. 2023. 13. 1. 12740-12740
  • Hitoshi Nakayama, Kei Hanafusa, Toshiyuki Yamaji, Eriko Oshima, Tomomi Hotta, Kenji Takamori, Hideoki Ogawa, Kazuhisa Iwabuchi. Phylactic role of anti-lipoarabinomannan IgM directed against mannan core during mycobacterial infection in macrophages. Tuberculosis (Edinburgh, Scotland). 2023. 102391-102391
  • Sara Grassi, Livia Cabitta, Simona Prioni, Laura Mauri, Maria Grazia Ciampa, Noriko Yokoyama, Kazuhisa Iwabuchi, Yana Zorina, Alessandro Prinetti. Identification of the Lipid Antigens Recognized by rHIgM22, a Remyelination-Promoting Antibody. Neurochemical research. 2023. 48. 6. 1783-1797
  • Motohide Murate, Noriko Yokoyama, Nario Tomishige, Ludovic Richert, Nicolas Humbert, Brigitte Pollet, Asami Makino, Nozomu Kono, Laura Mauri, Junken Aoki, et al. Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells. Cellular and molecular life sciences : CMLS. 2023. 80. 6. 167-167
  • 花房 慶, 竹田 浩章, 洪 慧馨, 柳田 光昭, 梅津 綾子, 狩野 航輝, 松尾 一郎, 中山 仁志, 平林 義雄, 岩渕 和久. 質量分析計によるホスファチジルグルコシドとその分子種の解析法の確立 低酸素による小胞体ストレス応答への関わり. 脂質生化学研究. 2023. 65. 204-206
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MISC (399):
  • 大野 瑛明, 山下 智大, 狩野 航輝, 岩渕 和久, 平林 義雄, 松尾 一郎, 上口 裕之, 中島 康晴, 津田 誠. GPR55は脊柱管狭窄に伴う好中球の浸潤と慢性疼痛の発症に寄与する. 日本整形外科学会雑誌. 2022. 96. 8. S1852-S1852
  • 村上和哉, 渡邊真衣, 花房慶, 中山仁志, 岩渕和久, 田中浩士. Synthesis and Functional Evalution of α(1,2) mannoside (Mannancap) to Bactericidal Evasion of Mycobacterium tuberculosis. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
  • 岩渕 和久. 感染症と免疫応答-糖脂質を介した自然免疫応答-. 化学と教育. 2021. 69. 11. 468-471
  • 王 迪, 工藤 綾子, 川上 和美, 岩渕 和久. 特別養護老人ホームに勤める看護師・介護職員のノロウイルス感染症対策を実施する際に遭遇した課題-Challenges Encountered with Norovirus Infection Control Among Nurses and Nursing Care Staff in Nursing Homes. 医療看護研究 = Journal of health care and nursing. 2021. 17. 2. 34-41
  • 花房慶, LI Xiaoja, 堀田知美, 大嶋恵理子, 中山仁志, 中山仁志, 狩野航輝, 松尾一郎, 伊藤拓夢, 上口裕之, et al. PhosphatidylGlueoside is involved in neutrophil homeostasis. 日本糖質学会年会要旨集. 2021. 40th
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Books (3):
  • 臨床看護学用語辞典
    医学芸術社 2002
  • Assays of sphingosine-dependent kinase for 14-3-3 protein.(共著)
    Sphingolipid metabolism and cell signaling, Part B In : Methods in Enzymology. 2000
  • Separation of glycosphingolipid-enriched microdomains from caveolar membrane characterized by presence of caveolin.(共著)
    Sphingolipid metabolism and cell signaling, Part B In : Methods in Enzymology. 2000
Works (2):
  • 血小板由来好中球接着能阻害因子(AIF)に関する研究
    1902 - 1996
  • Study on platelet-derived neutrophil-adherent inhibiting factor
    1902 - 1996
Education (4):
  • - 1986 Osaka University
  • - 1986 Osaka University Graduate School, Division of Pharmaceutical Sciences
  • - 1984 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
  • - 1984 Tokyo University of Science Faculty of Pharmaceutical Science
Professional career (2):
  • Ph.D. (Juntendo University)
  • Master degree (Osaka University)
Work history (14):
  • 2023/04 - 現在 Juntendo University Preparation office for establishment of the Faculty of Pharmacy Specially Appointed Professor
  • 2010/04 - 現在 理化学研究所 脳科学研究センター 客員研究員
  • 2022/02 - 2023/03 Juntendo University Graduate School of Medicine Professor
  • 2007/04 - 2023/03 Juntendo University
  • 2007/04 - 2023/03 Juntendo University Faculty of Health Care and Nursing
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Committee career (6):
  • 2012/10 - 現在 セラミド研究会 顧問
  • 2010/07 - 現在 日本脂質生化学会 幹事
  • 2008/09 - 現在 日本糖質学会 評議員
  • 2006/10 - 現在 日本生化学会 評議員
  • 2006/07 - 現在 日本炎症・再生医学会 評議員
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Association Membership(s) (6):
アメリカSciety for Leukocyte Biology ,  FCCA ,  アメリカ生化学・分子生物学会 ,  日本糖質学会 ,  日本炎症学会 ,  日本生化学会
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