2019 - 2024 Multimode autophagy: Diverse pathways and selectivity
2018 - 2021 Monitoring autophagy dynamics in vivo using innovative tools
2018 - 2020 p62によるオートファジーとストレス応答制御の統合的理解
2015 - 2018 International Activities Support for Autophagy Research
2015 - 2018 Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine
2015 - 2018 Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical application
2015 - 2018 Crosstalk between stress granules and autophagy in protein degradation
2015 - 2018 Morphofunctional analyses of autophagy for understanding the mechanism of the isolation membrane formation
2013 - 2018 Study on selective autophagy on cellular functions
2013 - 2018 Multidisciplinary research on autophagy: from molecular mechanisms to disease states
2014 - 2017 Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
2014 - 2017 Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer
2014 - 2017 Autophagy and metabolic regulation by multiple transcription factors
2014 - 2016 Physiological role of Ufm1 system
2013 - 2016 Does Spin1 mediate L-leucine-effects to ameliorate impaired autophagy?
2013 - 2016 Phosphorylation of p62/Sqstm1 activates Nrf2 during selective autophagy
2012 - 2015 Morphological and functional analyses of isolation membrane-associated tubules
2011 - 2014 Therapeutic strategy for the polyglutamine diseases by selective degradation of expanded polyglutamine proteins using polyglutamine-binding pepetides
2011 - 2013 The application of autophagy to prevent inner ear damage
2010 - 2012 Molecular mechanisms of p62 degradation in selective autophagy
2010 - 2012 Clarify the role of autophagy in influenza A virus infection andreplication
2009 - 2011 Bioimaging of mitochondrial dynamics and generation of model mice
2009 - 2010 オートファジーアクセサリー分子群の遺伝学的機能解析
2009 - 2010 オートファジーの破綻によるヒト病態発症機序の解明
2009 - 2010 Effects of mitophagy on cell death in Parkinson's disease model cells
2006 - 2010 Dynamics of autophagy and its physiological roles
2008 - 2009 封入体形成因子p62の代謝と病態発症
2008 - 2009 凝集体形成分子p62による神経変性疾患封入体形成機構
2006 - 2007 ユビキチン様分子による異常蛋白質代謝の解明
2006 - 2007 オートファジーによる選択的なユビキチン化蛋白質輸送機構の解明
2005 - 2005 ニューロンにおける品質管理の遺伝学的解析
2004 - 2005 ユビキチン様分子による異常蛋白質除去機構の解明
2001 - 2005 Studies on proteolysis mediated by the proteasomes and ubiquitin
Ryosuke Ishimura, Sota Ito, Gaoxin Mao, Satoko Komatsu-Hirota, Toshifumi Inada, Nobuo N. Noda, Masaaki Komatsu. Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control. Science Advances. 2023. 9. 33
Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu-Hirota, Ritsuko Arai, Elena Ryzhii, et al. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response. The EMBO journal. 2023. e113349