Rchr
J-GLOBAL ID：200901080774774868   Update date: Dec. 18, 2025

Takai Kazuyuki

タカイ カズユキ | Takai Kazuyuki
Affiliation and department：
Ehime University Graduate School of Science and Engineering, Department of Applied Chemistry

About Ehime University Graduate School of Science and Engineering, Department of Applied Chemistry


Job title： Professor
Homepage URL  (2)： http://www.ach.ehime-u.ac.jp/kako/index.htm ,  https://sites.google.com/site/takailabopen/
Research field  (1)： Molecular biology
Research keywords  (11)： 生化学 ,  分子生物学 ,  構成的生物学 ,  「細胞を創る」 ,  合成生物学 ,  無細胞生命科学 ,  biochemistry ,  molecular biology ,  constitutional biology ,  synthetic biology ,  cell-free sciences
Research theme for competitive and other funds  (11)：
  • 2014 - 2016 Combining eukaryotic chaperonins with the translation system from Escherichia coli
  • 2011 - 2014 Constitutive approach to the translation system from wheat
  • 2008 - 2009 タンパク質合成系の再構成に向けたコムギ胚芽翻訳因子の分画
  • 2005 - 2006 Molecular Evolution of RNA modification enzymes and RNA recognition mechanism
  • 2004 - 2005 Nucleoside modification and evolution of the wobble rule
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Papers (81)：
  • Haruyuki Furukawa, Ryota Yamagami, Yuto Nagashio, Kensuke Tsutsumi, Kazuki Goto, Takumi Nishioka, Takumi Kondo, Keigo Hisamatsu, Takeru Aga, Ryunosuke Watanabe, et al. Recombinant expression and purification of wheat aminoacyl-tRNA synthetases and IRES-dependent polypeptide synthesis with homogeneously derived purified factors. Biochimie. 2025. 236. 30-44
  • Riko Sugita, Vincent Guérineau, David Touboul, Satoko Yoshizawa, Kazuyuki Takai, Chie Tomikawa. tRNAValallows four-way decoding with unmodified uridine at the wobble position inLactobacillus casei. RNA. 2024. 30. 12. 1608-1619
  • Haruyuki Furukawa, Yuto Nagashio, Kensuke Tsutsumi, Naofumi Matsubara, Ryohei Kato, Chie Tomikawa, Kazuyuki Takai. Recombinant expression and purification of phenylalanyl-tRNA synthetase from wheat: a long-lasting poly(U)-dependent poly(Phe) synthesis system. Preparative biochemistry & biotechnology. 2024. 1088-1097
  • Yasuha Nagato, Seisuke Yamashita, Azusa Ohashi, Haruyuki Furukawa, Kazuyuki Takai, Kozo Tomita, Chie Tomikawa. Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria. Journal of biochemistry. 2023
  • Yasuha Nagato, Chie Tomikawa, Hideyuki Yamaji, Akiko Soma, Kazuyuki Takai. Intron-dependent or independent pseudouridylation of precursor tRNA containing atypical introns in Cyanidioschyzon merolae. International Journal of Molecular Sciences. 2022. 23. 20. 12058-12058
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MISC (130)：
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Books (7)：
  • Cell-free protein production: Methods and protocols. Methods in Molecular Biology 607
    Humana Press, a part of Springer Science+Business Media 2010
  • Cell-free protein production: Methods and protocols. Methods in Molecular Biology 607
    Humana Press, a part of Springer Science+Business Media 2010
  • ノーベル賞の生命科学入門 RNAが拓く新世界
    講談社 2009
  • "Structural Genomics, Part A", Advances in Protein Chemistry and Structural Biology, Vol. 75
    Elsevier Inc. 2008
  • "Structural Genomics, Part A", Advances in Protein Chemistry and Structural Biology, Vol. 75
    Elsevier Inc. 2008
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Lectures and oral presentations  (65)：
  • 乳酸菌Lactobacillus caseiにおけるAUAコドン翻訳の特異性
    (第48回日本分子生物学会年会 2025)
  • Development of a GUI Application for Designing and Editing Recombinant Protein Expression Plasmids
    (2025)
  • コムギタンパク質合成系の再構成
    (第47回日本分子生物学会年会 2024)
  • A reconstituted wheat translation system
    (29th tRNA Conference 2024)
  • Lactobacillus casei adopts four-way decoding without modification at the tRNA wobble position
    (29th tRNA Conference 2024)
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Works (1)：
  • 無細胞タンパク質合成系の保健衛生および畜産分野への応用
    2005 - 2005
Education (2)：
  • 1988 - 1993 University of Tokyo School of Science Department of Biophysics and Biochemistry
  • - 1993 The University of Tokyo Graduate School, Division of Science
Professional career (1)：
  • 博士(理学) (東京大学)
Committee career (5)：
  • 2018/10 - 2019/10 「細胞を創る」研究会 会長
  • 2016/11 - 2019/10 「細胞を創る」研究会 評議員
  • 2017/10 - 2018/10 「細胞を創る」研究会 副会長
  • 2007 - 2007 「細胞を創る」研究会 発起人
  • 1998 - 1998 日本RNA学会 設立発起人
Association Membership(s) (5)：
Protein Science Society of Japan ,  JAPAN RADIOISOTOPE ASSOCIATION ,  「細胞を創る」研究会 ,  日本分子生物学会 ,  日本生化学会
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