Rchr
J-GLOBAL ID：200901080900195895   Update date: Apr. 18, 2024

Sugiura Reiko

スギウラ レイコ | Sugiura Reiko
Affiliation and department：
Kindai University Faculty of Pharmacy Department of Pharmaceutical Sciences

About Kindai University Faculty of Pharmacy Department of Pharmaceutical Sciences


Job title： Professor
Homepage URL  (1)： https://www.phar.kindai.ac.jp/genome/
Research field  (4)： Pharmaceuticals - health and biochemistry ,  Cell biology ,  Applied molecular and cellular biology ,  Pharmacology
Research keywords  (22)： Disordered protein ,  ストレス応答 ,  細胞死 ,  ゲノム薬理学 ,  ケミカルバイオロジー ,  液ー液相分離 ,  ストレス顆粒 ,  カルシニューリン ,  分裂酵母 ,  免疫制御 ,  MAPキナーゼ ,  細胞内輸送 ,  RNA結合タンパク質 ,  分子遺伝学 ,  タンパク質リン酸化 ,  シグナル伝達 ,  RNAバイオロジー ,  転写制御 ,  モデル生物 ,  ゲノム創薬 ,  カルシウムシグナル ,  分子標的治療薬
Research theme for competitive and other funds  (38)：
  • 2019 - 2023 Mechanisms of cancer-specific apoptosis induction targeting ERK hyperactivation
  • 2011 - 2015 Regulatory mechanisms of MAPK signaling and its application to chemicalgenomics
  • 2008 - 2014 Comprehensive promotion of research on RNA program
  • 2008 - 2012 Regulatory mechanism of the cell integrity signaling mediated by mRNA-binding proteins
  • 2007 - 2010 Molecular Genetic Analysis of the MAPK Signaling Pathway
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Papers (234)：
  • Teruaki Takasaki, Yasuyuki Hamabe, Kenta Touchi, Golam Iftakhar Khandakar, Takeshi Ueda, Hitoshi Okada, Kazuko Sakai, Kazuto Nishio, Genzoh Tanabe, Reiko Sugiura. ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells. Oxidative medicine and cellular longevity. 2024. 2024. 7683793-7683793
  • Reiko Sugiura, Ryosuke Satoh, Naofumi Tomimoto, Teruaki Takasaki. Phase Separation Orchestrates Cancer Signaling: Stress Granules as a Promising Target for Cancer Therapy. Phase Separation in Living Cells. 2023. 209-252
  • Teruaki Takasaki, Ryosuke Utsumi, Erika Shimada, Asuka Bamba, Kanako Hagihara, Ryosuke Satoh, Reiko Sugiura. Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast. Microbial cell (Graz, Austria). 2023. 10. 6. 133-140
  • Golam Iftakhar Khandakar, Yoichi Miyamoto, Ryosuke Satoh, Kenta Kishimoto, Mingzuo Xie, Mengyu Shih, Teruaki Takasaki, Genzoh Tanabe, Masahiro Oka, Reiko Sugiura. ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023
  • Reiko Sugiura. Cutting Edge Developments in RNA Biology for the Control of Gene Expression. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2023. 46. 2. 138-138
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MISC (121)：
  • 山田南, 杉本恵崇, 黒崎亮, 高崎輝恒, 佐藤亮介, 杉浦麗子. Valproic acid impacts aggregation and toxicity associated with α-Synuclein overproduction~Crosstalk between α-synuclein and membrane traffic and glycosylation~. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 吉田展康, 川崎有紀, 原信樹, 佐藤亮介, 高崎輝恒, 杉浦麗子. Relationship between phosphorylation of a KH-type RNA-binding protein Rnc1 and its translocation to stress granules. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 田中達也, 佐藤亮介, 高崎輝恒, 杉浦麗子, 杉浦麗子. Role of the DNA damage response protein BRAT1 in the ROS mediated induction of cell death induced by a novel anticancer compound ACAGT-007a. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 萩原加奈子, 萩原加奈子, 佐藤亮介, 前田拓也, 杉浦麗子. Effects of an immune modulator FTY720 (fingolimod) on signaling pathways that control cell proliferation in fission yeast. 衛生薬学・環境トキシコロジー講演. 2023. 2023
  • 巽祐司, 高崎輝恒, 杉本恵崇, 黒崎亮, 山田南, 壽美月, 佐藤亮介, 杉浦麗子. α-synが引き起こす細胞死を増強する細胞内輸送経路のステップの特定. 日本薬理学雑誌. 2023. 158. Supplement
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Patents (21)：
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Books (6)：
  • 図解腫瘍薬学
    南山堂 2020 ISBN:9784525721619
  • 酵母の生命科学と生物工学 : 産業応用から基礎科学へ (DOJIN BIOSCIENCE SERIES)
    化学同人 2013 ISBN:4759815082
  • 岩波 生物学辞典 第5版
    岩波書店 2013 ISBN:400080314X
  • Welcome toゲノムワールド-ゲノム創薬科学最前線
    京都廣川書店 2010 ISBN:4901789376
  • 医薬品の開発と生産-レギュラトリーサイエンスの基礎 薬学教育モデル・コアカリキュラムC17分野国家試 (学教育モデル・コアカリキュラムC17分野国家試験対応テキスト)
    じほう 2010 ISBN:4840741301
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Lectures and oral presentations  (507)：
  • Valproic acid impacts aggregation and toxicity associated with α-Synuclein overproduction~Crosstalk between α-synuclein and membrane traffic and glycosylation~
    (2023)
  • Relationship between phosphorylation of a KH-type RNA-binding protein Rnc1 and its translocation to stress granules
    (2023)
  • Role of the DNA damage response protein BRAT1 in the ROS mediated induction of cell death induced by a novel anticancer compound ACAGT-007a
    (2023)
  • The mechanism of alfa-Synuclein aggregation and toxicity revealed by the fission yeast model system: The role of calcineurin signaling and its relevance to Parkinson's disease
    (2021)
  • Chemical genetic screen for medicines targeting the aggregation and cytotoxicity of α-synuclein using a fission yeast model of Parki
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Works (1)：
  • Feedback regulation of MAPK signalling by an RNA-binding protein
    2003 -
Professional career (1)：
  • Doctor of Philosophy (Medical Sciences) (Kobe University)
Work history (3)：
  • 2020/10 - 現在 近畿大学大学院 薬学研究科長
  • 2004/04 - 現在 Kindai University Faculty of Pharmacy
  • 2012/10 - 2020/09 Kindai University Faculty of Pharmacy, Department of Pharmaceutical Sciences
Awards (5)：
  • 2018/06 - 神戸大学 優秀研究者賞
  • 2004/03 - 上原記念生命科学振興財団 上原記念生命科学振興財団 研究奨励賞
  • 2001 - 日本薬理学会学術奨励賞
  • 2000 - 神戸大学医学部優秀学術論文賞
  • 1999 - 神戸大学医学部優秀学術論文賞
Association Membership(s) (10)：
THE JAPANESE CANCER ASSOCIATION ,  JAPANESE ASOCIATION FOR PROTEIN PHOSPHATASE RESEARCH ,  THE SOCIETY OF JAPANESE WOMEN SCIENTISTS ,  THE RNA SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  YEAST GENETICS SOCIETY OF JAPAN ,  日本分子生物学会 ,  日本薬理学会 ,  日本生化学会 ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER
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