Kuwahara Kazuhiko

クワハラカズヒコ | Kuwahara Kazuhiko

Affiliation and department：

Research field (1)： Human pathology

Research keywords (3)：抗体医薬 , 転写共役型DNA傷害 , 乳癌

Research theme for competitive and other funds (7)：

2020 - 2023 A novel strategy by PARP inhibitors for sporadic breast cancers
2016 - 2018 TREX2複合体機能不全の誘導は抗がん剤感受性亢進の標的になるのか
2015 - 2018 非遺伝性散発性乳癌の発症、悪性進展におけるTREX2複合体因子の機能解析
2012 - 2015 転写に共役したDNA傷害に起因する新規乳癌発症機構の解析
2009 - 2012 非遺伝性乳癌におけるp53 mRNA核外輸送分子GANPの機能

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Papers (64)：

Misa Kojima, Masatomo Kimura, Kazuhiko Kuwahara, Hisatomo Tamaki, Ryuji Yasumatsu, Sota Sadamoto, Takayuki Shinohara, Kazuki Amemiya, Yoshitsugu Miyazaki, Akihiko Ito. Rare finding of mucorales sporangia and chlamydospores in tissue. Pathology International. 2024
Andri Rezano, Naomi Gondo, Yasuhiro Sakai, Yuko Nakamura, Suchada Phimsen, Tokio Tani, Akihiko Ito, Seiji Okada, Kazuhiko Kuwahara. Tumorigenesis and Augmented Chemosensitivity Caused by Aberrant Expression of the Components in the Mammalian TREX-2 Complex. 2024
Yasuhiro Sakai, Kazuhiko Kuwahara. Carcinogenesis caused by transcription-coupled DNA damage through GANP and other components of the TREX-2 complex. Pathology International. 2024
Kazuhiko Kuwahara. DNA Damage, DNA Repair, and Cancer: Second Edition. International Journal of Molecular Sciences. 2023
Kazuhiko Kuwahara. DNA Damage, DNA Repair, and Cancer: Second Edition. International Journal of Molecular Sciences. 2023

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MISC (23)：

Kazuhiko Kuwahara, Hidemi Ito, Kiyotaka Kuzushima, Hiroji Iwata, Hideo Tanaka, Keitaro Matsuo. Molecular epidemiological studies of germinal center-associated nuclear protein (ganp) in the development of human sporadic breast cancers. CANCER RESEARCH. 2016. 76
Andri Rezano, Kazuhiko Kuwahara, Mutsuko Yamamoto-Ibusuki, Masahiro Kitabatake, Penpak Moolthiya, Suchada Phimsen, Taiji Suda, Shigenobu Tone, Yutaka Yamamoto, Hirotaka Iwase, et al. DSS1 as potential prognostic marker for breast cancer progression and relapse-free patient survival. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2014. 34. S114-S114
戸田哲平, 桑原一彦, 近藤直幸, 前田洋助, 松田善衛, 阪口薫雄. HIV-1 gp120/CD4&CXCR4膜融合複合体エピトープと感染阻止効果. 日本エイズ学会誌. 2011. 13. 4. 342-342
KASAMA YURI, SEKIGUCHI SATOSHI, SAITO MAKOTO, SATO MASAAKI, KUWAHARA KAZUHIKO, TAKEYA MOTOHIRO, SAKAGUCHI NOBUO, KOHARA MICHINORI, KOHARA KYOKO. 全長HCVのB細胞発現によるリンパ腫誘導. 生化学. 2010. 83回・33回. ROMBUNNO.2T11-7-7
KAZAMA YURI, SEKIGUCHI SATOSHI, SAITO MAKOTO, SATO MASAAKI, KUWAHARA KAZUHIKO, TAKEYA MOTOHIRO, SAKAGUCHI NOBUO, KOHARA MICHINORI, KOHARA KYOKO. マウスモデルを用いたC型肝炎ウイルス誘発Bリンパ腫発生機序の解析. 日本ウイルス学会学術集会プログラム・抄録集. 2010. 58th. 268

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Patents (3)：

胆管がん特異的糖鎖エピトープを認識するモノクローナル抗体
GANP蛋白質
高病原性トリインフルエンザに対する抗体

Lectures and oral presentations (3)：

The role of mammalian TREX2 complex in sporadic breast cancers.
(The 3rd Bandung International Biomolecular Medicine Conference (BIBMC) 2014)
DNA傷害の新たな視点 -mRNA輸送分子GANP欠損による転写共役型DNA損傷と発癌の実証-
(佐賀大学分子生命科学セミナー 2012)
New Insights of transcription-coupled DNA damage in cell development and differentiation.
(Special seminar in Department of Biochemistry, Faculty of Medicine, Khon Kaen University 2011)

Works (1)：

SARSウィルスに対するB細胞応答の研究
2004 -

Education (2)：

1990 - 1994 Saga Medical School
1983 - 1989 Saga Medical School

Professional career (1)：

Doctor of Medicine (Saga Medical School)

Work history (11)：

2022/04 - 現在 Kindai University Department of Diagnostic Pathology, Kindai University Hospital
2021/04 - 2022/03 Fujita Health University School of Medicine Department of Diagnostic Pathology
2018/04 - 2021/03 Fujita Health University School of Medicine Department of Diagnostic Pathology Assistant Professor
2016/08 - 2018/03 Niigata University Graduate School of Medical and Dental Sciences
2016/02 - 2016/07 Hirosaki University University Hospital

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Committee career (3)：

2021/04 - 現在日本病理学会学術評議員
2016/01 - 現在日本癌学会評議員
2011/07 - 現在日本がん分子標的治療学会評議員

Awards (11)：

2022/11 - 日本病理学会学術研究賞演説(A演説)
2018/10 - 藤田学園医学会産学連携推進センター長賞
2015 - 愛知健康増進財団医学研究・健康増進活動等研究助成金
2015 - 第24回日本医学会総会記念医学振興基金研究助成金
2014 - 愛知県がん研究振興会がんその他の悪性新生物研究助成金

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Association Membership(s) (5)：

日本臨床細胞学会 , American Association of Cancer Research , THE JAPANESE SOCIETY OF PATHOLOGY , THE JAPANESE CANCER ASSOCIATION , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER

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