Rchr
J-GLOBAL ID：200901081198302420   Update date: Oct. 17, 2024

Ninomiya Haruaki

ニノミヤ ハルアキ | Ninomiya Haruaki
Affiliation and department：
Tottori University

About Tottori University


Job title： Professor
Homepage URL  (1)： http://www.ninomiya.med.tottori-u.ac.jp/homepage/
Research field  (4)： Clinical pharmacy ,  Physiology ,  Pathobiochemistry ,  Medical biochemistry
Research keywords  (5)： コレステロール ,  ニーマン・ピック ,  Neurophysiology ,  Neurochemistry・Neuropharmacology ,  Phavmacology in General
Research theme for competitive and other funds  (27)：
  • 2015 - 2017 ニーマン・ピックC1ライク1依存性コレステロール輸送におけるORP10の役割
  • 2008 - 2010 NPC1-L1蛋白質細胞内局在のコレステロールによる制御メカニズムの研究
  • 2006 - 2007 Mechanism on Hsp70-induced stabilization of ion channel and its application to the treatment for atrial fibrillation
  • 2006 - 2007 Quality control and degradation mechanisms of NPC1
  • 2006 - 2007 ニーマンピックC1 蛋白質のユビキチン化に関する研究
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Papers (89)：
  • Hiroyuki Minato, Ryo Endo, Yasutaka Kurata, Tomomi Notsu, Yoshiharu Kinugasa, Takayuki Wakimizu, Motokazu Tsuneto, Yasuaki Shirayoshi, Haruaki Ninomiya, Kazuhiro Yamamoto, et al. Azelnidipine protects HL-1 cardiomyocytes from hypoxia/reoxygenation injury by enhancement of NO production independently of effects on gene expression. Heart and vessels. 2024. 39. 10. 899-908
  • Tomomi Notsu, Yasutaka Kurata, Haruaki Ninomiya, Fikri Taufiq, Koji Komatsu, Junichiro Miake, Tatsuya Sawano, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome. Inhibition of the uric acid efflux transporter ABCG2 enhances stimulating effect of soluble uric acid on IL-1β production in murine macrophage-like J774.1 cells. Hypertension Research. 2023
  • Satoshi Miyazaki, Toshihiro Hamada, Tadahiro Isoyama, Shinichi Okada, Katsuyuki Tomita, Yusuke Endo, Masanari Kuwabara, Shinobu Sugihara, Kazuhide Ogino, Haruaki Ninomiya, et al. Characterization of Urate Metabolism and Complications of Patients with Renal Hypouricemia. Internal medicine (Tokyo, Japan). 2022. 62. 13. 1915-1920
  • Peili Li, Yasutaka Kurata, Fikri Taufiq, Masanari Kuwabara, Haruaki Ninomiya, Katsumi Higaki, Motokazu Tsuneto, Yasuaki Shirayoshi, Miguel A Lanaspa, Ichiro Hisatome. Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes. Molecular biology reports. 2022. 49. 7. 5939-5952
  • Satoshi Miyazaki, Toshihiro Hamada, Shinobu Sugihara, Einosuke Mizuta, Yusuke Endo, Akira Ohtahara, Koji Komatsu, Masanari Kuwabara, Tomoko Fukuuchi, Kiyoko Kaneko, et al. Xanthinuria Type 1 with a Novel Mutation in Xanthine Dehydrogenase and a Normal Endothelial Function. Internal Medicine. 2022. 61. 9. 1383-1386
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MISC (58)：
  • 李 佩俐, 加藤 克, 小倉 一能, 三明 淳一朗, 倉田 康孝, 山本 康孝, 加藤 雅彦, 足立 正光, 井川 修, 平岡 昌和, et al. 熱ショックによる活動電位短縮の分子機構. 心電図. 2010. 30. Suppl.4. S-4
  • 李 佩俐, 白吉 安昭, 久留 一郎, 三明 淳一朗, 加藤 克, 井川 修, 平岡 昌和, 二宮 治明, 倉田 康孝. HERGチャネルの成熟化過程に及ぼすHsp70とHsc70の異なる役割に関する研究. 心電図. 2009. 29. Suppl.3. S-3
  • Bahrudin Udin, Morisaki Hiroko, Morisaki Takayuki, Carrier Lucie, Ninomiya Haruaki, Nanba Eiji, Igawa Osamu, Mizuta Einosuke, Miake Junichiro, Yamamoto Yasutaka, et al. 1 Role of the Ubiquitin Proteasome System in the Development of Heart Failure in Hypertrophic Cardiomyopathy(Young Investigator's Award for International Students Finalists Lecture (YIA International),Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society). Circulation journal : official journal of the Japanese Circulation Society. 2008. 72. 74-74
  • M. Suzuki, Y. Sugimoto, Y. Ohsaki, K. Ohno, H. Ninomiya. Roles of toll-like receptor 4, proinflammatory cytokines and STATs in the pathogenesis of Niemann-Pick disease type C. JOURNAL OF INHERITED METABOLIC DISEASE. 2006. 29. 147-147
  • Li Peili, Ogino Kazuhide, Hoshikawa Yoshiko, Morisaki Hiroko, Cheng Jidong, Tooyama Keiko, Morisaki Takayuki, Hashimoto Kiyoshi, Ninomiya Haruaki, Shigemasa Chiaki, et al. OE-193 Exaggeration of Remote Reperfusion Pulmonary Injury in AMP Deaminase 3 Knockout Mice(Metabolism/Biochemistry/Energetics-1 (H) OE33,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society). Circulation journal : official journal of the Japanese Circulation Society. 2006. 70. 197-197
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Books (6)：
  • N教授の生理学講義ノート
    日本医事新報社 2016
  • 標準臨床検査学 基礎医学 人体の構造と機能
    医学書院 2015
  • ニーマン・ピック病C型の診断と治療
    医薬ジャーナル 2015
  • 神経回路網形成障害を中心とした脳発達障害研究の進歩
    じほう出版 2003
  • 分子生物学への招待
    三共出版 2002
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Lectures and oral presentations  (12)：
  • NPC1/NPC2の構造と機能
    (日本小児神経学会学術集会 2013)
  • Intracellular cholesterol transport mediated by NPC1/NPC1-Like1
    (2011)
  • Proteasomal degradation of NPC1
    (Annual Scientific Conference on NPC 2007)
  • ニーマン・ピック病C型細胞での脂質輸送障害とシグナル伝達の変化
    (形態科学シンポジウム 2005)
  • 細胞内脂質輸送の障害と神経細胞の障害修復機構
    (日本生化学会中部支部例会 2005)
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Works (6)：
  • 筋ジストロフィーに関連する疾患の病態解明と治療法の開発に関する研究
    2002 - 2004
  • Pathophysiology of muscle dystrophy and related disordens
    2002 - 2004
  • 筋ジストロフィー及び関連疾患の病態解明と治療法開発に関する研究
    1999 - 2001
  • Pathophysiology of muscle dyotrophy and related disorders
    1999 - 2001
  • 筋ジストロフィーの分子病態学的基礎研究
    1996 - 1998
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Education (4)：
  • - 1990 Kyoto University
  • - 1990 Kyoto University Graduate School, Division of Medicine
  • - 1983 Kyoto University Faculty of Medicine Department of Medical Science
  • - 1983 Kyoto University Faculty of Medicine
Professional career (1)：
  • Medical Docter (Kyoto University)
Work history (9)：
  • 2008 - 現在 Tottori University Faculty of Medicine
  • 1998 - 2001 Tottori University Faculty of Medicine
  • 1998 - 2001 Associate Professor, Department of Neurobiology, Tottori University Faculty of Medicine
  • 1993 - 1998 Kyoto University Faculty of Medicine
  • 1993 - 1998 Assistant professor, Department of Pharmacology Faculty of Medicine, Kyoto University
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Association Membership(s) (1)：
THE JAPANESE BIOCHEMICAL SOCIETY
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