Research theme for competitive and other funds (11):
2020 - 2025 クロスリンク反応を利用したポリケタイド合成酵素の構造解析
2017 - 2020 Recognition mechanism of carrier protein by acyltransferase
2018 - ポリケタイド生合成におけるアシルキャリアータンパク質認識機構の解析
2017 - 2018 ヒタチマイシン生合成におけるポストPKS反応の解析
2015 - 2017 Structural and functional analysis of acyltransferase that possesses a unique substrate specificity
2015 - 2017 非天然マクロラクタム化合物の微生物発酵生産
2013 - 2015 Structural and functional analysis of ATP-dependent ligases in macrolactam biosynthesis
2014 - 2015 タンパク質間相互作用解析を指向したクロスリンク法開発
2013 - 2014 多機能型シトクロム P450 モノオキシゲナーゼ GfsF の構造機能研究
2009 - 2011 海洋放線菌の二次代謝産物生合成酵素の機能解析
2005 - 2005 カビ・キノコの新規糖質関連酵素のX線結晶構造解析
Show all
Papers (77):
Kosei Sone, Takehiro Ito, Chihaya Yamada, Toma Kashima, Akimasa Miyanaga, Naoko Ohkama-Ohtsu, Shinya Fushinobu. Crystal structure of plant γ-glutamyl peptidase 1 with dual roles in sulfur metabolism and implications for oxidative stress regulation. 2024
Fumitaka Kudo, Kazuma Tsuboi, Mutsumi Ikezaki, Daiki Nagayama, Koichi Kawamura, Taishi Ando, Akimasa Miyanaga, Tadashi Eguchi. The Post-Polyketide Synthase Modification Mechanism in Hitachimycin Biosynthesis. Chembiochem : a European journal of chemical biology. 2024. e202400405
Dawei Wang, Akimasa Miyanaga, Taichi Chisuga, Fumitaka Kudo, Tadashi Eguchi. Engineering the Substrate Specificity of (S)-β-Phenylalanine Adenylation Enzyme HitB. Chembiochem : a European journal of chemical biology. 2024. e202400383
Ippei Watanabe, Akimasa Miyanaga. Substrate Specificity of Chondroitinase ABC-I Based on Analyses of Biochemical Reactions and Crystal Structure. Trends in Glycoscience and Glycotechnology. 2023. 35. 208. E94-E99
Akimasa Miyanaga, Kenji Nagata, Joji Nakajima, Taichi Chisuga, Fumitaka Kudo, Tadashi Eguchi. Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis. ACS Chemical Biology. 2023. 18. 11. 2343-2348
Structural analysis of two unique adenylation enzymes in the biosynthesis of β-amino acid-containing macrolactam polyketides
(10th US-Japan Seminar on the biosynthesis of Natural Products 2024)
THE SOCIETY FOR ACTINOMYCETES JAPAN
, PROTEIN SCIENCE SOCIETY OF JAPAN
, THE CHEMICAL SOCIETY OF JAPAN
, JAPAN SOCIETY FOR BIOSICENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY