Research field (4)：
Cell biology
, Rehabilitation science
, Genetics
, Pathobiochemistry
Research keywords (3)：
リハビリテーション医学
, 病理学
, 分子生物学
Research theme for competitive and other funds (18)：
2024 - 2027 骨転移患者のリハビリテーションに応用できる薬剤の探索
2021 - 2024 腫瘍細胞の特性を利用した滑膜肉腫の術後患肢機能を高める薬剤の探索
2013 - 2015 Analysis of forced rotation of transcription cycle in cancer cells
2009 - 2011 Search for New Cancer Cell Growth Pathway
2005 - 2009 Comparative Analysis of the DECODE Systems in Hematopoiesis and Oxidative Stress Response
2004 - 2004 タイ寄生虫感染関連胆道がんの症例・対照研究による遺伝子多型の解析
2003 - 2004 Analysis for New Cell Cycle Regulation
1999 - 2003 Molecular mechanisms of generation of pleiotropic effects of recombination genes
2002 - 2002 転写制御複合体形成のダイナミクスとその生物機能の解明
1999 - 1999 クロマチン構造を介した転写調節機構の解明
1998 - 1999 減数分裂期組換えの機能解析
1998 - 1999 組換え蛋白質複合体の精製と機能解析
1997 - 1999 組換えに関する染色体構造の機能解析
1998 - 1998 クロマチン構造を介した組換え反応の機能解析
1998 - 1998 クロマチン構造を介した転写調節機構の解明
1998 - 1998 ヒトHIV・インテグレース補助する宿主核内因子SWI蛋白質の機能解析
1997 - 1997 クロマチン構造を介した組換え反応の機能解析
1997 - 1997 クロマチン構造変化を介した転写調節機構の解明
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Papers (80)：
De Hu, Hidetaka Yamada, Katsuhiro Yoshimura, Tsutomu Ohta, Kazuo Tsuchiya, Yusuke Inoue, Kazuhito Funai, Takafumi Suda, Yuji Iwashita, Takuya Watanabe, et al. High Expression of Fas-Associated Factor 1 Indicates a Poor Prognosis in Non-Small-Cell Lung Cancer. Current oncology (Toronto, Ont.). 2023. 30. 11. 9484-9500
Hiroko Natsume, Kinga Szczepaniak, Hidetaka Yamada, Yuji Iwashita, Marta Gędek, Jelena Šuto, Keiko Ishino, Rika Kasajima, Tomonari Matsuda, Felix Manirakiza, et al. Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan). Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2023. 45. 1. 1-1
Toru Sengoku, Masaaki Shiina, Kae Suzuki, Keisuke Hamada, Ko Sato, Akiko Uchiyama, Shunsuke Kobayashi, Asako Oguni, Hayato Itaya, Kota Kasahara, et al. Structural basis of transcription regulation by CNC family transcription factor, Nrf2. Nucleic Acids Research. 2022. 50. 21. 12543-12557
Kazuo Tsuchiya, Katsuhiro Yoshimura, Yuji Iwashita, Yusuke Inoue, Tsutomu Ohta, Hirofumi Watanabe, Hidetaka Yamada, Akikazu Kawase, Masayuki Tanahashi, Hiroshi Ogawa, et al. m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer. Cancer Gene Therapy. 2022. 29. 10. 1355-1372
ンジタケーラ・オギシテ, マニラキザ・フエリックス, 石川 励, 太田 力, 岩下 雄二, ルグウィザゴンガ・ベルゾン, 山田 英孝, 椙村 春彦. ルワンダの胃がんのTP53変異プロフィールの評価(Evaluation of TP53 mutation profiles of gastric cancer in Rwanda, Africa). 日本病理学会会誌. 2022. 111. 1. 226-226
Hidetaka Yamada, De Hu, Keiko Ishino, Tsutomu Ohta, Moriya Iwaizumi, Takao Hinoi, Akihiro Sakurai, Kohji Tanakaya, Shinya Oda, Tomoki Kosho, et al. Germline mutations of CDH1 gene in hereditary diffuse gastric cancer in Japanese population. CANCER SCIENCE. 2021. 112. 665-665
High expression of FAF1 indicates a poor prognosis in non-small-cell lung cancer
(2024)
Elucidation of the transcriptional regulation mechanism of the transcription factor Nrf2 involved in the development of lung cancer
(2023)
Development of treatments for CIC-rearranged sarcomas: Multiplex kinase activity analysis and drug screening using patient-derived cancer models
(HUPO World Congress 2023 Busan 2023)
Development of treatments for CIC-rearranged sarcomas: Multiplex kinase activity analysis and drug screening using patient-derived cancer models
(2023)
Elucidation of the transcriptional regulation mechanism of the transcription factor Nrf2 involved in the development of lung cancer
(第81回日本癌学会学術総会 2022)
