Rchr
J-GLOBAL ID：200901081454394249   Update date: Dec. 03, 2025

Isobe Naoki

イソベ ナオキ | Isobe Naoki
Affiliation and department：
Hiroshima University .

About Hiroshima University .


Research field  (1)： Animal production science
Research keywords  (9)： Innate immunity ,  Mastitis ,  feces ,  milk ,  hormone ,  immunohistochemistry ,  Somatic cell count ,  EIA ,  mammary gland
Research theme for competitive and other funds  (26)：
  • 2024 - 2028 Detection of probiotic bacteria for the production of robust chicks and development of optimal administration methods
  • 2024 - 2028 物理的刺激を起点として乳腺上皮細胞の乳分泌を調節する機構の解明
  • 2024 - 2027 乳房炎の炎症ステージに伴い変化する乳中白血球機能及び抗菌物質の特定とその応用
  • 2023 - 2026 Effect of eating and ruminating behavior on individual variation in enteric methane emission of dairy cows
  • 2021 - 2025 物理化学的刺激を感知するTRPチャネルが乳腺組織の形態形成と乳分泌を制御する機構
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Papers (228)：
  • Nishimura, K., Hirabayashi, H., Kawashima, K., Okimura, T., Suzuki, A., Asakuma, S., Isobe, N., Obitsu, T., Kushibiki, S., Sugino, T. Effect of medium-chain fatty acid supplementation on feed intake, rumen fermentation, blood profile, and milk production of dairy cows in the transition period. JOURNAL OF DAIRY SCIENCE. 2025. 108. 4. 4381-4389
  • Furukido, Rin, Tsuka, Takeshi, Kurokawa, Yuzo, Isobe, Naoki, Suzuki, Naoki. Association of iron-acquisition-related genes and milk lactoferrin concentration with the growth of Escherichia coli and Klebsiella pneumoniae in milk of dairy cows. MICROBIAL PATHOGENESIS. 2025. 200
  • Jin-Kun Sun, Zi-Long Liang, Takahiro Nii, Naoki Suzuki, Naoki Isobe. Antimicrobial Component Concentrations in the Milk of Peripartum Goats. Animal Science Journal. 2025. 96. 1
  • Naoki Suzuki, Naoki Isobe. Determining causal pathogens and inflammatory state of mastitis in dairy cows via Gram staining of precipitates in milk. Frontiers in Veterinary Science. 2025. 11
  • Marufah, Nur Laili, Nii, Takahiro, Suzuki, Naoki, Jaisue, Jirapat, Isobe, Naoki. Interleukin 1 Receptor Antagonist (IL-1ra) Production and Expression Dynamics in Mammary Glands After Lipopolysaccharide Infusion. ANIMAL SCIENCE JOURNAL. 2025. 96. 1. e70047
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MISC (24)：
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Patents (3)：
  • バイオサーファクタントの利用
  • バイオサーファクタントの利用
  • バイオサーファクタントの利用
Books (8)：
  • Dairy Japan
    Dairy Japan 2025
  • 乳牛の消化と吸収
    Dairy Japan社 2021
  • Dairy Japan
    Dairy Japan社 2020
  • Dairy Japan
    Dairy Japan社 2020
  • Mammary management using antimicrobial peptides
    2020
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Lectures and oral presentations  (75)：
  • 「乳房炎と繁殖機能との関係」
    (家畜感染症学会シンポジウム 2024)
  • ~乳房炎診断の新局面~ 「乳房炎原因菌の検出率アップを目指す」
    (産業動物学術ハイブリッドセミナー 2023)
  • 乳房炎診断の新たな局面~ その菌,死んでませんか?
    (第8回広島大学酪農技術セミナー 2023)
  • Continued Intrauterine Lipopolysaccharide Infusion: Its Effect on Goat Mastitis.(Nov. 8-9, Yogyakarta, Indonesia)
    (10th Internatinal seminorof tropical Animal Production (ISTAP) 2023)
  • Decrease in viable bacterial counts by leukocytes during preservation of milk from mastitic dairy cows.
    (10th Internatinal seminorof tropical Animal Production (ISTAP) 2023)
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Education (4)：
  • 1993 - 1996 Hiroshima University Graduate School, Division of Biophere Sciences
  • 1993 - 1996 Hiroshima University Graduate School, Division of Biophere Sciences
  • 1987 - 1991 Hiroshima University Faculty of Applied Biological Science
  • 1987 - 1991 Hiroshima University Faculty of Applied Biological Science
Professional career (2)：
  • Doctor of Agriculture (Hiroshima University)
  • Master of Agriculture (Hiroshima University)
Work history (4)：
  • 2021/04 - 広島大学大学院統合生命科学研究科 教授
  • 2005/04 - 広島大学大学院生物圏科学研究科 助教授
  • 1996/08/01 - 2005/03/31 Hiroshima University Graduate School for International Development and Cooperation Research Associate
  • 1996/08/01 - 2005/03/31 Graduate School for International Development and Cooperation Research Associate
Committee career (12)：
  • 2021/04/01 - 2031/03/31 中四国乳房炎協議会 幹事
  • 2018/04/01 - 2028 日本畜産学会 編集委員
  • - 2024/10 Japan Mastitis Council Japan Mastitis Council Dean
  • 2023/07 - 2024/06 日本畜産学会 優秀発表賞受賞候補者選考委員会委員
  • 2023/06 - 2024/02 酪農学園大学 事業推進委員
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Awards (15)：
  • 2024 - Wiley Top Cited Article 2022-2023 Differences in antimicrobial components between bacterial culture-positive and -negative bovine clinical mastitis milk.
  • 2023/11/18 - English Presentation Award Effect of milking time on yield, composition and antimicrobial component in milk of lactating goats.
  • 2023/09/19 - English Presentation Award Leukocytes function in goat milk after intrauterine infusion of lipopolysaccharide.
  • 2022/08/26 - President of AAAP Outstanding Student competition Award Effect of Continual Intrauterine Infusion of Lipopolysaccharide on Mastitis in Goats
  • 2021/09/28 - Japan Animal Science Association English Presentation Award Relationship between milk Ig level and inflammation status induced by intramammary infusion of E.coli
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Association Membership(s) (7)：
Japanese Society of Veterinary Science ,  Chushikoku Mastitis Council ,  The American Dairy Science Association ,  Japanese Association of Mastitis ,  Japanese Association of Animal Reproduction ,  Kansai Association of Animal Science ,  Japanese Association of Animal Science
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