Rchr
J-GLOBAL ID:200901081697508692   Update date: Sep. 19, 2024

Hatada Izuho

Hatada Izuho
Affiliation and department:
Research field  (2): Systems genomics ,  Genomics
Research keywords  (9): epigenetics, imprinting, methylation ,  methylation ,  imprinting ,  epigenetics ,  メチル化 ,  インプリンティング ,  エピジェネティクス ,  ゲノム編集 ,  エピゲノム編集
Research theme for competitive and other funds  (31):
  • 2021 - 2025 The role of epigenome and epitranscriptome in the development of obesity
  • 2021 - 2024 膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明
  • 2020 - 2023 Histone methyltransferase KMT2 mutation-induced epigenomic abnormalities and endometrial cancer development and progression
  • 2017 - 2020 A new therapeutic strategy for autoimmune diseases through epigenome editing
  • 2016 - 2019 Analysis of the paternal transmission of obesity.
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Papers (227):
  • Ryosuke Kobayashi, Yuki Tajika, Junki Kohmaru, Sumiyo Morita, Takuro Horii, Yoichi Mizukami, Shizu Aikawa, Yasushi Hirota, Izuho Hatada. The histone methyltransferase KMT2D is essential for embryo implantation via regulating precise differentiation of endometrial cells. Cell Death Discovery. 2024. 10. 1
  • Tsugunori Maruyama, Sho Matsui, Ryosuke Kobayashi, Takuro Horii, Yasuo Oguri, Satoshi Tsuzuki, Takahiro Horie, Koh Ono, Izuho Hatada, Tsutomu Sasaki. Medium-Chain Triglycerides-Specific Appetite is Regulated by the β-oxidation of Medium-Chain Fatty Acids in the Liver. American Journal of Physiology-Endocrinology and Metabolism. 2024
  • Hayato Kawabata, Ayumu Konno, Yasunori Matsuzaki, Yumika Sato, Mika Kawachi, Ryo Aoki, Saki Tsutsumi, Shota Togai, Ryosuke Kobayashi, Takuro Horii, et al. Improving cell-specific recombination using AAV vectors in the murine CNS by capsid and expression cassette optimization. Molecular Therapy - Methods & Clinical Development. 2024. 32. 1. 101185-101185
  • Chaomulige, Toshihiko Matsuo, Kohei Sugimoto, Mary Miyaji, Osamu Hosoya, Masashi Ueda, Ryosuke Kobayashi, Takuro Horii, Izuho Hatada. Morphometric Analysis of the Eye by Magnetic Resonance Imaging in MGST2-Gene-Deficient Mice. Biomedicines. 2024. 12. 2. 370-370
  • Sumiyo Morita, Takuro Horii, Mika Kimura, Ryosuke Kobayashi, Hiroki Tanaka, Hidetaka Akita, Izuho Hatada. A Lipid Nanoparticle-Based Method for the Generation of Liver-Specific Knockout Mice. International Journal of Molecular Sciences. 2023. 24. 18. 14299-14299
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MISC (80):
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Patents (2):
  • ゲノムDNAのメチレーションサイトのメチル化検出用バイオチップ及び検出方法
  • ゲノムDNAのメチル化検出方法
Books (10):
  • 「特集」ゲノム編集法の新常識! : CRISPR/Casが生命科学を加速する
    羊土社 2014 ISBN:9784758101295
  • Reprogrammed parthenogenetic ES cells - New choice for regenerative medicine.
    InTech 2011
  • Reprogrammed parthenogenetic ES cells - New choice for regenerative medicine.
    InTech 2011
  • The Epigenomics of Cancer: In An Omics Perspective on Cancer Research
    Springer 2010
  • The Epigenomics of Cancer: In An Omics Perspective on Cancer Research
    Springer 2010
more...
Lectures and oral presentations  (58):
  • p53 Suppresses Tetraploid Development in Mice
    (SCIENTIFIC REPORTS 2015)
  • 半数体胚由来2倍体ES細胞(hddES)の再生医療への利用の可能性
    (日本エピジェネティクス研究会 2013)
  • CRISPR/Casと半数体ES細胞を用いたトリプルノックアウトおよび大規模染色体欠失の作製
    (日本繁殖生物学会 2013)
  • 低酸素培養は初期胚にエピジェネティック異常を引き起こす
    (日本エピジェネティクス研究会 2012)
  • 初期胚の低酸素培養は初期胚や胎盤にDNAメチル化異常を引き起こす
    (日本繁殖生物学会 2012)
more...
Professional career (1):
  • PhD (Osaka University)
Work history (1):
  • Gunma University Associate Professor
Committee career (3):
  • - 現在 日本ゲノム編集学会 将来計画委員会委員
  • - 現在 日本エピジェネティクス研究会 幹事
  • - 現在 全国大学等遺伝子研究支援施設連絡協議会 副代表幹事
Association Membership(s) (5):
日本RNAi研究会 ,  日本エピジェネティクス研究会 ,  日本癌学会 ,  日本分子生物学会 ,  日本ゲノム編集学会
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