Shimizu Ichiro

• 肝線維化と肝発癌に及ぼす酸化ストレスと女性ホルモンの影響の研究
• 肝発癌に及ぼすエストロゲンに関する研究
• 肝線維化に及ぼす酸化ストレスの分子生物学的研究
• C型肝炎ウイルス(HCV)と肝癌発生に関する分子生物学的研究
• Effects of oxidative stress and female sex hormones on hepatic fibrogenesis and carcinogenesis
Study of estrogens on hepatocarcinogenesis
Molecular biological study of oxidative stress on hepatic fibrosis
Molecular biological study on the relationship of HCV with hepatocarcinogenesis

• T Itagaki, Shimizu, I, Cheng, X, Y Yuan, A Oshio, K Tamaki, H Fukuno, H Honda, Y Okamura, S Ito. Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells. GUT. 2005. 54. 12. 1782-1789
• Takahiro Horie, Ichiro Shimizu, Michiyo Okazaki, Kensuke Fujiwara, Soichiro Fujiwara, Koji Yamamoto, Arata Iuchi, Akihito Tanagami, Mitsuyoshi Hirokawa, Susumu Ito. A patient with adult extrahepatic portal obstruction, of which distinction from intrahepatic cholangiocarcinoma was difficult. Journal of Medical Investigation. 2005. 52. 3-4. 203-207
• Tatsuhiko Shiraishi, Ichiro Shimizu, Takahiro Horie, Michiyo Okazaki, Momoko Teraoka, Kazunori Takeichi, Kouzou Uehara, Kensuke Fujiwara, Soichiro Fujiwara, Hirofumi Yamamoto, et al. A patient with octopus pot-shaped cardial cancer that metastasized to multiple organs. Journal of Medical Investigation. 2005. 52. 1-2. 122-125
• 肝星細胞における酸化ストレスを介したTGF-β発現に及ぼすエストラジオールとプロゲステロンの作用. 医学と薬学. 2005. 53 (1): 96-98
• 針刺し・切り傷の予防と暴露後感染予防法. 臨床医. 2005. 31 (8): 1431-1433

ｍore...

• Developing therapeutic strategies for hepatic fibrosis
  In: Liver Diseases: Biochemical Mechanisms and New Therapeutic Insights. Eds. Ali S, Friedman SL, Mann DA, Science Publishers, Enfield, New Hampshire 2006
• 可溶型TGF-βII型受容体の肝星細胞活性化抑制作用
  細胞療法の基礎と臨床,アークメデイア、東京 2004
• Recent therapeutic developments in hepatic fibrosis
  In: Cellular and Molecular Basis of Fibrinogenesis. Ed. Razzaque M, Landes Bioscience, Georgetown 2004
• Sho-Saiko-To
  In: Herbal Medicines: Molecular Basis in Health and Disease. Ed. Packer L, Marcel Dekker, Inc, New York 2004
• 女性と肝線維化
  ダイナミック・メデイシン第4巻(下条文武、斎藤 康編集) 2003

ｍore...

• 新規薬物によるヘリコバクター・プロリ除菌療法
  2003 -
• New strategy for eradiation therapy of <i>Helicobacter Pylori</i>
  2003 -
• 漢方薬の肝細胞保護作用とNF-кB抑制を介した肝星細胞活性化抑制作用に関する検討
  2000 -
• Effects of herbal medicine on the activation of hepatic stellate cells by inactivation of NF-кB and by protection against hepatocyte injury
  2000 -

• - 1980 Ehime University School of Medicine
• - 1980 Ehime University Faculty of Medicine

• PhD (The University of Tokushima)

• 1994 - 2002 Instructor, Second Department of Internal
• 2002 - - Associate Professor, Department of Digestive and
• 1991 - 1994 Research Associate, Second Department of
• 1989 - 1991 Postdoctoral Fellow, Department of
• 1985 - 1987 Research Associate, Department of Laboratory
Cardiovascular Medicine, University of Tokushima
Medicine, Tokushima, Japan
Medicine, Univercity of Tokushima School of
School of Medicine, Tokushima, Japan
Internal Medicine, University of Tokushima
School of Medicine, Philadelphia, PA, U.S.A.
Microbiology, University of Pennsylvania
Tokushima, Japan
Medicine, Univercitiy of Tokushima,

• 日本消化器集団検診学会 地方会評議員
• 日本肝臓学会 評議員
• 日本消化器病学会 評議員
• 日本消化器内視鏡学会 評議員
• 日本内科学会 地方評議員
American Association for the Study of Liver Disease member
American Gastroenterological Association member

• 1999 - 平成11年度Liver Forum in Kyoto 研究奨励賞
• 1998 - 日本消化器病学会奨励賞
• 1996 - 康楽賞
• 1991 - 財団法人工藤学術財団研究奨励賞

日本環境感染症学会 ,  American Association for the Study of Liver Disease ,  American Gastroenterological Association ,  日本臨床生理学会 ,  日本超音波医学会 ,  日本消化器集団検診学会 ,  日本肝臓学会 ,  日本消化器病学会 ,  日本消化器内視鏡学会 ,  日本内科学会 ,  American Association for the Study of Liver Disease ,  American Gastroenterological Association