Rchr
J-GLOBAL ID:200901082335360251   Update date: Mar. 20, 2024

Kubo Shuji

クボ シュウジ | Kubo Shuji
Affiliation and department:
Job title: Laboratory head
Other affiliations (2):
Research field  (3): Fetal medicine/Pediatrics ,  Virology ,  Medical biochemistry
Research keywords  (6): Cancer virotherapy ,  細胞治療 ,  遺伝子治療 ,  Viral vectors ,  Cell therapy ,  Gene therapy
Research theme for competitive and other funds  (21):
  • 2023 - 2026 脳梗塞後の組織修復・再生における脳傷害/虚血誘導性幹細胞による老廃物除去の役割
  • 2021 - 2025 播種性癌に対する革新的な自殺遺伝子ウイルス療法の開発
  • 2019 - 2022 Development of virotherapy for osteosarcoma pulmonary metastases using stem cells as carriers
  • 2018 - 2021 Development of cell transplantation therapy using human injury/ischemia-induced neural stem/progenitor cells
  • 2016 - 2019 Development of retroviral replicating vector-mediated suicide gene therapy for malignant mesothelioma
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Papers (67):
  • Emiko Sonoda-Fukuda, Yuya Takeuchi, Nao Ogawa, Shunsuke Noguchi, Toru Takarada, Noriyuki Kasahara, Shuji Kubo. Targeted Suicide Gene Therapy with Retroviral Replicating Vectors for Experimental Canine Cancers. International Journal of Molecular Sciences. 2024. 25. 5. 2657-2657
  • Lisa Isoda, Emiko Sonoda-Fukuda, Hiroaki Fujino, Toru Takarada, Kosei Hasegawa, Noriyuki Kasahara, Shuji Kubo. Therapeutic Efficacy of Prodrug Activator Gene Therapy Using Retroviral Replicating Vectors for Human Ovarian Cancer. Anticancer research. 2023. 43. 12. 5311-5317
  • 平野 佳伸, 中込 隆之, 土居 亜紀子, 久保 秀司, 湊 雄介, 澤野 俊憲, 都築 建三, 阪上 雅史. ミクログリアがマウス脳梗塞巣由来傷害/虚血誘発性神経幹細胞に及ぼす影響. 脳循環代謝. 2023. 35. 1. 116-116
  • Hiroaki Fujino, Emiko Sonoda-Fukuda, Lisa Isoda, Ayane Kawabe, Toru Takarada, Noriyuki Kasahara, Shuji Kubo. Retroviral Replicating Vectors Mediated Prodrug Activator Gene Therapy in a Gastric Cancer Model. International journal of molecular sciences. 2023. 24. 19
  • Yoshinobu Hirano, Takayuki Nakagomi, Akiko Nakano-Doi, Shuji Kubo, Yusuke Minato, Toshinori Sawano, Masafumi Sakagami, Kenzo Tsuzuki. Microglia Negatively Regulate the Proliferation and Neuronal Differentiation of Neural Stem/Progenitor Cells Isolated from Poststroke Mouse Brains. Cells. 2023. 12. 16
more...
MISC (37):
  • S. Kubo, M. Takagi-Kimura, N. Kasahara. Retroviral replicating vector-mediated prodrug activator gene therapy in an experimental model of human osteosarcoma. HUMAN GENE THERAPY. 2017. 28. 12. A28-A29
  • Masatoshi Tagawa, Thao T. T. Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, et al. An Inhibitor for the MDM2-p53 Interaction Produces Synergistic Cytotoxicity with Oncolytic Adenoviruses on Mesothelioma with Wild-Type p53 Genotype. MOLECULAR THERAPY. 2017. 25. 5. 280-280
  • Shuji Kubo, Misato Takagi-Kimura, Noriyuki Kasahara. Prodrug Activator Gene Therapy Using Retroviral Replicating Vectors in an Experimental Model of Human Osteosarcoma. MOLECULAR THERAPY. 2017. 25. 5. 61-61
  • Y. Tada, T. T. Nguyen, S. Kubo, M. Shingyoji, I. Sekine, K. Tatsumi, H. Shimada, K. Hiroshima, M. Tagawa. E1B-55kDa-defective adenoviruses produced cytotoxicity in combination with MDM2 inhibitors on INK4A/ARF-defective mesothelioma. HUMAN GENE THERAPY. 2016. 27. 11. A89-A89
  • S. Kubo, Y. Mawatari-Furukawa, N. Kasahara. Customization of virotherapy with retroviral replicating vectors on the basis of cellular receptor expression profiles. HUMAN GENE THERAPY. 2016. 27. 11. A82-A82
more...
Education (2):
  • - 1998 Kumamoto University
  • - 1989 Hokkaido University School of Medicine
Professional career (1):
  • 医学博士 (熊本大学)
Association Membership(s) (7):
日本癌学会 ,  日本分子生物学会 ,  日本人類遺伝学会 ,  日本小児科学会 ,  日本遺伝子細胞治療学会 ,  米国遺伝子細胞治療学会 ,  欧州遺伝子細胞治療学会
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