Rchr
J-GLOBAL ID：200901082522797078
Update date: Feb. 01, 2024
Sotomaru Yusuke
ソトマル ユウスケ | Sotomaru Yusuke
Affiliation and department：
Job title：
教授
Research field (1)：
Laboratory animal science
Research keywords (3)：
哺乳動物
, 核移植
, 生殖工学
Research theme for competitive and other funds (25)：
- 2018 - 2020 胚盤胞補完法による臓器特異的疾患モデルマウスの開発
- 2017 - 2019 希少難治性疾患に対する画期的な医薬品医療機器等の実用化に関する研究:薬事承認を目指すシーズ探索研究(ステップ0)
- 2017 - 2018 遺伝子改変マーモセットの効率的生産に向けた生殖工学技術の整備・開発
- 2016 - 2018 ウイルス感染は筋萎縮性側索硬化症(ALS)の発症に関与するか?
- 2015 - 2018 Role of polymeric OPN on fibrosis
- 2015 - 2018 Cancer fluid biopsy for childhood malignancies using one cell analysis
- 2016 - 2017 遺伝子改変マーモセットの効率的生産に向けた生殖工学技術の整備・開発
- 2015 - 2016 遺伝子改変マーモセットの汎用性拡大および作出技術の高度化とその脳科学への応用
- 2014 - 2015 遺伝子改変マーモセットの汎用性拡大および作出技術の高度化とその脳科学への応用
- 2013 - 2015 Comprehensive analysis of egg-specific reprograming factors based on cell cycle-specific localization
- 2015 - 生殖系列における性特異的エピゲノム制御の解明
- 2012 - 2014 Detection of molecular targets for childhood cancers using genomics and cellomics: targeting for cancer stem cells
- 2010 - 2014 Analysis of Epigenome Marks and Transcriptome in the Germ Line by the Next Generation Sequencer
- 2010 - 2013 Establishment of the novel mouse model of metastatic colorectalcancer and identification of the biomarker for tissue-specific metastasis
- 2010 - 2012 Molecular analysis for developing the newtargeting therapy in Japanese Pediatric Liver Tumor study group
- 2008 - 2012 先端的遺伝子導入・改変技術による脳科学研究のための独創的霊長類モデルの開発と応用
- 2009 - 2011 Elucidation of development mechanism and molecular targets in neuroblastoma and hepatoblastoma using genomics and cellomics
- 2010 - 2010 次世代シークエンサーを用いた生殖細胞におけるエピゲノム修飾の全ゲノムマッピング
- 2007 - 2008 神経芽腫のがん幹細胞研究:分化・退縮と発生・増殖・進展の二極化規定因子か?
- 2006 - 2008 Regulation of germ line function and development by genomic imprinting
- 2006 - 2007 Establishment of preclinical study system for regenerative medicine using somatic nuclear transferred embryonic stem cells
- 2004 - 2005 Studies on developmental aberration of somatic clones by global gene expression analysis
- 2004 - 2005 クローン技術を応用した遺伝子組み換えラット作出に関する研究
- 2003 - 2005 Development of genetic and microbiological quality control system of mouse embryonic stem cell lines.
- 2003 - 2004 Basic studies on animal model for regenerative medicine using severe immunodeficient mice.
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Papers (50)：
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Li, Rongzhi, Sano, Tomomi, Mizokami, Akiko, Fukuda, Takao, Shinjo, Takanori, Iwashita, Misaki, Yamashita, Akiko, Sanui, Terukazu, Nakatsu, Yusuke, Sotomaru, Yusuke, et al. miR-582-5p targets Skp1 and regulates NF-Kappa B signaling-mediated inflammation. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2023. 734
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Hiyama, Yoko, Yamaoka, Emi, Fukazawa, Takahiro, Kojima, Masato, Sotomaru, Yusuke, Hiyama, Eiso. In Vitro Transfection of Up-Regulated Genes Identified in Favorable-Outcome Neuroblastoma into Cell Lines. CELLS. 2022. 11. 19
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Masuda, Shun, Tanaka, Shigeru, Shiraki, Hiroko, Sotomaru, Yusuke, Harada, Kana, Hide, Izumi, Kiuchi, Yoshiaki, Sakai, Norio. GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice. NEUROBIOLOGY OF DISEASE. 2022. 172
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Yoshimoto, Yuki, Uezumi, Akiyoshi, Ikemoto-Uezumi, Madoka, Tanaka, Kaori, Yu, Xinyi, Kurosawa, Tamaki, Yambe, Shinsei, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Sotomaru, Yusuke, et al. Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte Differentiation. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022. 10
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Ikeda, Shinya, Tanaka, Koki, Ohtani, Reiko, Kanda, Akifumi, Sotomaru, Yusuke, Kono, Tomohiro, Obata, Yayoi. Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes. JOURNAL OF REPRODUCTION AND DEVELOPMENT. 2022. 68. 2. 125-136
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Books (3)：
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マーモセットラボマニュアル はじめての取扱いから研究最前線まで
アドスリー 2018 ISBN:9784904419786
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こころの働きと病・覚醒剤-2007~2009世界脳週間の講演より-
株式会社 クバプロ 2010 ISBN:9784878051074
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幹細胞・クローン研究プロトコール 中辻憲夫編
羊土社 2001 ISBN:4897069351
Lectures and oral presentations (86)：
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Y染色体の存在がマウス雌性生殖系列に及ぼす影響
(第113回日本繁殖生物学会大会 2020)
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マウス過剰排卵処置におけるPMSG投与時期の影響
(第67回日本実験動物学会総会(紙上開催、ポスター) 2020)
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Stepwise differentiation of ScxGFP iPS cells into mature tenocytes and ligamentocytes
(2019)
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マウス過剰排卵処置におけるPMSG投与のタイミングについて
(日本実験動物技術者協会関東支部REG部会第20回特別講演会 2019)
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Effect of cetrorelix acetate administration on ovarian stimulation in aged mice.
(14th FELASA Congress 2019)
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Education (4)：
- 1996 - 1998 Kinki University Graduate School, Division of Agricultural Science Graduate School, Division of Agricultural Science
- 1991 - 1993 Tokyo University of Agriculture Graduate School, Division of Agriculture Animal Science
- 1987 - 1991 Tokyo University of Agriculture Faculty of Agriculture
- 1987 - 1991 Tokyo University of Agriculture Faculty of Agriculture
Professional career (2)：
- Doctor of Philosophy (Tokyo University of Agriculture)
- Master (Tokyo University of Agriculture)
Work history (7)：
- 2013/04/01 - Hiroshima University Vice Director, Natural Science Center for Basic Research and Development
- 2011/04/01 - Hiroshima University Natural Science Center for Basic Research and Development Professor
- 2007/04/01 - 2011/03/31 Hiroshima University Natural Science Center for Basic Research and Development Associate Professor
- 2005/02/16 - 2007/03/31 Hiroshima University Natural Science Center for Basic Research and Development Associate Professor
- 2004/04/01 - 2005/02/15 Central Institute for Experimental Animals Office Director
- 2001/04/01 - 2004/03/31 Central Institute for Experimental Animals Researcher
- 1998/04/01 - 1999/03/31 Kinki University Research Associate
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Association Membership(s) (6)：
JAEAT
, 日本実験動物学会
, 日本分子生物学会
, 日本繁殖生物学会
, 日本畜産学会
, Japan Society for Ova Research
