Hari Yoshiyuki

ハリヨシユキ | Hari Yoshiyuki

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://p.bunri-u.ac.jp/lab06/index.html

Research field (2)： Pharmaceuticals - chemistry and drug development , Biochemistry

Papers (110)：

Kazuki Yamamoto, Yasufumi Fuchi, Yuta Ito, Yoshiyuki Hari. Expansion of Phosphoramidite Chemistry in Solid-Phase Oligonucleotide Synthesis: Rapid 3′-Dephosphorylation and Strand Cleavage. Journal of Organic Chemistry. 2023. 88. 5. 2726-2734
Yuta Ito, Koichi Mizuno, Sanae Sumise, Airi Kimura, Nozomi Noguchi, Yasufumi Fuchi, Yoshiyuki Hari. Generation of 4′-Carbon Radicals via 1,5-Hydrogen Atom Transfer for the Synthesis of Bridged Nucleosides. Organic Letters. 2022. 24. 41. 7696-7700
Misa Shoji, Yasufumi Fuchi, Takashi Osawa, Han Kim, Yuta Ito, Yoshiyuki Hari. Synthesis and Properties of Oligonucleotides Containing 2'-O,4'-C-Methyleneoxy-Bridged Pyrimidine Derivatives. The Journal of organic chemistry. 2022. 87. 17. 11743-11750
Yuta Ito, Yoshiyuki Hari. Synthesis of Nucleobase-Modified Oligonucleotides by Post-Synthetic Modification in Solution. Chemical record (New York, N.Y.). 2022. 22. 5. e202100325
Yuta Ito, Yoshiyuki Hari. Synthesis of Nucleobase-Modified Oligonucleotides by Post-Synthetic Modification in Solution. Chemical Record. 2022

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MISC (7)：

Yoshiyuki Hari. Bridged Nucleosides as Building Blocks of Oligonucleotides: Synthesis and Properties. HETEROCYCLES. 2020. 100. 5. 681-717
Duplex-forming ability. 2016. 74. 2. 169-169
Yoshiyuki Hari, Satoshi Obika. Synthesis and Properties of 2’,4’-Bridged Nucleic Acids Containing Multiple Heteroatoms in the Bridges. Journal of Synthetic Organic Chemistry, Japan. 2016. 74. 2. 141-153
Yoshiyuki Hari. Development of Artificial Nucleic Acid That Recognizes a CG Base Pair in Triplex DNA Formation. YAKUGAKU ZASSHI. 2013. 133. 11. 1201-1208
Yoshiyuki Hari, Satoshi Obika, Takeshi Imanishi. Towards the Sequence-Selective Recognition of Double-Stranded DNA Containing Pyrimidine-Purine Interruptions by Triplex-Forming Oligonucleotides. European Journal of Organic Chemistry. 2012. 2012. 15. 2875-2887

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Books (7)：

核酸科学ハンドブック
講談社 2020
2'-C,4'-C-Ethyleneoxy-bridged 2'-deoxyribonucleic acids (EoDNAs) with thymine nucleobases: Synthesis, duplex-forming ability and enzymatic stability
Humana Press 2019
2',4'-Bridged nucleic acids containing plural heteroatoms in the bridge moiety
Springer Singapore 2018
Site-specific modification of nucleobases in oligonucleotides
Springer Singapore 2018
2',4'-Bridged nucleic acids for targeting double-stranded DNA
Springer 2016

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Education (2)：

1997 - 2002 Osaka University Graduate School of Pharmaceutical Sciences
1993 - 1997 Osaka University School of Pharmaceutical Sciences

Professional career (1)：

PhD (Osaka University)

Work history (8)：

2015/04 - 現在 Tokushima Bunri University Faculty of Pharmaceutical Sciences
2013/04 - 2015/03 Osaka University Graduate School of Pharmaceutical Sciences
2009/01 - 2013/03 Osaka University Graduate School of Pharmaceutical Sciences
2008/04 - 2009/01 Nagoya City University Graduate School of Pharmaceutical Sciences
2007/04 - 2008/03 Nagoya City University Graduate School of Pharmaceutical Sciences

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Association Membership(s) (5)：

THE CHEMICAL SOCIETY OF JAPAN , Japan Society of Nucleic Acids Chemistry , The Nucleic Acids Therapeutics Society of Japan , The Society of Synthetic Organic Chemistry, Japan , The Pharmaceutical Society of Japan

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