Rchr
J-GLOBAL ID:200901082641854187
Update date: Apr. 16, 2024
Yoshizaki Tomokazu
ヨシザキ トモカズ | Yoshizaki Tomokazu
Affiliation and department:
Research field (1):
Otorhinolaryngology
Research theme for competitive and other funds (37):
- 2021 - 2024 新規生物学的コンセプトを応用した頭頸部ウイルス発癌超早期治療法の開発
- 2019 - 2022 Epidemiological studies on environmental chemicals as risk factors for chronic sinusitis, including nasal polyps
- 2017 - 2021 Analysis of oncogenesis and heterogenesity in nasopharyngeal carcinoma and development of novel therapy
- 2017 - 2021 Elucidating the mechanism for induction of senescence-associated secretory phenotype by Epstein-Barr virus
- 2017 - 2020 Development of CTC capture chip for head and neck cancer patients
- 2016 - 2020 内因性免疫による頭頸部ウイルス発癌における内分泌撹乱物質の関与と新規治療法の開発
- 2016 - 2018 Establishment tailor-made therapy of head and neck cancer by single cell analysis
- 2015 - 2018 Association between activation induced cytidine deaminase and HPV positive oropharyngeal carcinogenesis
- 2014 - 2017 Analysis for the role of cell competition in the tumorigenesis and treatment strategy of nasopharyngeal carcinoma
- 2014 - 2017 Elucidation of mechansim to form pre-metastatic niche in nasopharyngeal carcinoma and development of exosome for its treatment
- 2014 - 2017 Therapeutic approach to recurrent respiratory papillomatosis from the perspective of signal transduction of human papillomavirus
- 2014 - 2017 Bone invasion-targeted chemotherapy with Novel Anionic Platinum Complex (3Pt) in the Treatment of oral squamous cell carcinoma
- 2014 - 2016 A trial to isolate novel pathogenic viruses
- 2011 - 2015 The role of intrinsic immunity for EBV-mediated nasopharyngeal carcinogenesis
- 2011 - 2013 Cancer stem cell model and nasopharyngeal carcinogenesis
- 2011 - 2013 Tumor-targeted chemotherapy with the nanopolymer-based drug NC-6004 for oral squamous cell carcinoma
- 2009 - 2012 Research of the mechanism of lymph node metastasis in nasopharyngeal carcinoma with bio-assay model
- 2008 - 2010 New therapeutic approach for nasopharyngeal carcinoma using induction of Epstein-Barr virus lytic cycle by anti-cancer chemotherapy
- 2007 - 2010 Molecular biological analysis of Siah1 in EBV related tumor including nasopharyngeal cancer
- 2006 - 2009 EBV gene expression profile which is affected by virus reactivation and oncogenesis of nasopharyngeal carcinoma.
- 2005 - 2007 Research on the mechanism of EBVLMP1-indused release of fibroblast growth factor2
- 2004 - 2006 The relationship between single nucleotide polymorphism of matrix metallopraeinase-1 and metastasis of nasopharyngeal carcinoma.
- 2004 - 2006 核酸アナログ系抗ウイルス剤によるウイルス関連腫瘍治療に関する基礎研究
- 2003 - 2005 Development of molecular targeting therapy for head and neck cancer by targeting membrane type MMP and EBV antigen
- 2001 - 2003 Molecular, biological studies on the mechanism of neck metastasis from nasopharyngeal carcinoma
- 2001 - 2002 Molecular mechanism of nasopharyngeal carcinoma oncogenesis by Epstein-Barr virus RNA EBERs
- 2000 - 2001 Study on mechanism of malignant transformation of epithelial cells by EB virus LMP1
- 1998 - 2000 Study for the aim of gene therapy of nasopharyngeal carcinoma
- 1997 - 1998 EBウイルス前初期遺伝子産物を標的とした上咽頭癌に対する遺伝子治療に関する研究
- 1996 - 1997 Quantitative analysis of Epstein-Barr virus immediate-early proteins and evaluation of its clinical role especially in nasopharyngeal
- 頭頸部がんの臓器温存治療
- 唾石症に対する体外衝撃波の応用
- 頭頸部癌における転移機構
- 上咽頭癌とエプスタイン バール ウイルスに関する研究
- Extracorporeal shock wave lithotripsy in salivary stones
- Mechanism of metastasis in head and neck cancer
- Study on Nasopharyngeal Carcinoma and Epstein-Barr Virus
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Papers (251):
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Masao Noda, Takayoshi Ueno, Ryota Koshu, Yuji Takaso, Mari Dias Shimada, Chizu Saito, Hisashi Sugimoto, Hiroaki Fushiki, Makoto Ito, Akihiro Nomura, et al. Performance of GPT-4V in Answering the Japanese Otolaryngology Board Certification Examination Questions: Evaluation Study. JMIR Medical Education. 2024. 10. e57054-e57054
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野田 昌生, 上野 貴雄, 甲州 亮太, 島田 Dias茉莉, 伊藤 真人, 矢本 成恒, 吉崎 智一, 野村 章洋. 耳鼻咽喉科専門医試験におけるGenerative Pretrained Transformerの有効性に関する検討. 日本耳鼻咽喉科頭頸部外科学会会報. 2023. 126. 11. 1217-1223
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Hirotomo Dochi, Satoru Kondo, Shigetaka Komura, Makiko Moriyama-Kita, Takeshi Komori, Asuka Nanbo, Miako Sakaguchi, Masaki Fukuyo, Toshihide Hamabe-Horiike, Mariko Tanaka, et al. Peritumoral SPARC expression induced by exosomes from nasopharyngeal carcinoma infected Epstein-Barr virus: A poor prognostic marker. International journal of cancer. 2023
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Mari Dias Shimada, Masao Noda, Ryota Koshu, Yuji Takaso, Hisashi Sugimoto, Makoto Ito, Tomokazu Yoshizaki, Osamu Hori. Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model. Scientific reports. 2023. 13. 1. 16741-16741
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Naohiro Wakisaka, Makiko Moriyama-Kita, Satoru Kondo, Eiji Kobayashi, Takayoshi Ueno, Yosuke Nakanishi, Kazuhira Endo, Hisashi Sugimoto, Tomokazu Yoshizaki. Immune-Related Gene Expression Profile at Peritumoral Tonsillar Tissue Is Modified by Oropharyngeal Cancer Nodal Status. The American journal of pathology. 2023
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MISC (412):
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溝上晴恵, 溝上晴恵, 岡部篤史, 近藤悟, 福世真樹, バハテヤリ ラヒムトラ, 吉崎智一, 金田篤志. Epigenetic aberrations in EBV-positive nasopharyngeal carcinoma. 日本消化器癌発生学会総会プログラム・抄録集. 2020. 31st
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青木由宇, 土定靖典, 近藤悟, 吉崎智一. 縦隔内リンパ節転移を伴う甲状腺乳頭癌の経験. 耳鼻咽喉科臨床 補冊. 2019. 154. 129
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加納亮, 近藤悟, 吉崎智一. HPV関連中咽頭癌の発癌・臨床像におけるAPOBECの役割. 頭頸部癌. 2019. 45. 2. 108
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中西庸介, 石川和也, 上野貴雄, 遠藤一平, 近藤悟, 脇坂尚宏, 吉崎智一. 治療戦略 頭頸部がん治療の均てん化と標準化の検証 地方大学における現状と頭頸部癌治療標準化への提言. 頭頸部癌. 2019. 45. 2. 118
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遠藤一平, 上野貴雄, 石川和也, 中西庸介, 近藤悟, 脇坂尚宏, 吉崎智一. DDS製剤の現状と頭頸部癌治療への展開. 頭頸部癌. 2019. 45. 2. 99
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Books (1):
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知っておきたい甲状腺診療-検査から専門治療まで- (MB ENTONI(エントーニ))
全日本病院出版会 2014 ISBN:4881179632
Education (4):
- - 1991 Kanazawa University
- - 1991 Kanazawa University Graduate School, Division of Medicine
- - 1986 Kanazawa University
- - 1986 Kanazawa University Faculty of Medicine
Professional career (1):
Work history (4):
- 2008/11 - 現在 金沢大学医学系教授(耳鼻咽喉科・頭頸部外科)
- 1997/10 - 2008/10 Kanazawa University Hospital
- 1995/10 - 1997/09 ノースカロライナ州立大学チャペルヒル校ポスドク
- 1994/04 - 1995/09 Kanazawa University Hospital
Awards (12):
- 2008 - 財団法人国際耳鼻咽喉科学振興会賞
- 2008 - SPIO award
- 2007 - 大阪癌研究会学術研究助成
- 2007 - がん集学的治療研究財団研究助成
- 2007 - 北國癌基金
- 2007 - Osaka Cancer Research Fund
- 2007 - Cancer treatment fund
- 2007 - Hokkoku Cancer Fund
- 2005 - 金沢大学十全医学賞
- 2005 - Zyuzen medical research award
- 2002 - 日本気管食道科学会奨励賞
- 2001 - とやま賞
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Association Membership(s) (4):
THE JAPAN BRONCHO-ESOPHAGOLOGICAL SOCIETY
, 日本がん学会
, JAPAN SOCIETY FOR HEAD AND NECK CANCER
, 日本耳鼻咽喉科学会
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