Research field (7)：
Nutrition and health science
, Anatomy
, Pharmacology
, Neuroscience - general
, Psychiatry
, Hygiene and public health (non-laboratory)
, Hygiene and public health (laboratory)
2016 - 2019 Development of novel antidepressants targetting lysophosphatidic-acid-signaling
2015 - 2017 Quantitative analysis of lysophosphatidic acid (LPA) in serum and cerebrospinal fluid of depressed patients
2014 - 2017 Investigation of the mechanisms on the emotional behaviors in mice via delta opioid receptors in prelimbic prefrontal cortex
2014 - 2017 Lysophosphatidic acid induces anxiety-like behavior via its receptors in mice
2013 - 2016 Development of a new suicide education program for social work students in Japan
2013 - 2016 A study on the therapeutic mechanisms of depression through a transcription factor MATH2 and its target gene Prg1.
2010 - 2012 Gene expression analysis in ventral and dorsal hippocampal dentate gyrus after 4 weeks treatment with sertraline
2010 - 2012 Prg1, regulated by MATH2, is an important factor for survival of neurons derived from neural stem cells
2008 - 2010 The investigation to Dynamin-1 for new antidepressats binding protein
2007 - 2009 An antidepressant related transcription factor Math2 regulates Prg1 expression and induces neurite differentiation.
2007 - 2008 The guide for points and issues of clinical trial with high-risk persons in suicidality
2006 - 2007 SCREENING FOR ANTIDEPRESSANT RELATED GENES RELATED TO NEUROGENESIS
2006 - 2007 The cloning and investigations for antidepressants affected protein with new chemical proteomics approach
2005 - 2006 THE EXPRESSION AND FUNCTION OF NOVEL GENE WITH RING H2 FINGER MOTIF IN VITRO AND IN VIVO.
2004 - 2006 Synthetic research on the actual condition of oral environment and function in mental disorder.
2004 - 2005 THE EXPRESSION OF SYNAPTIC VESICLE PROTEINS AFTER CHRONIC ANTIDEPRESSANT TREATMENT IN RAT BRAIN.
2002 - 2004 治療抵抗性うつ病の病態背景にあるヒト遺伝子多型の系統的探索
2002 - 2003 THE STUDY OF THE THERAPEUTIC MECHANISMS OF ANTIDEPRESSANT ON NEURONAL REMODELING
2001 - 2003 THE INVESTIGATION OF THE THERAPEUTIC MECHANISMS OF ANTIDEPRESSANT ON NEUROTRANSMITTER RELEASE
2000 - 2001 Ring fingerモチーフを有する新規遺伝子SRG34の分子生物学的研究
1999 - 2001 The study for molecular mechanisms of antidepressant.
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Papers (349)：
Yoshitaka Kawashima, Misa Yamada, Hiroki Furuie, Hiroshi Kuniishi, Kie Akagi, Tomoko Kawashima, Takamasa Noda, Mitsuhiko Yamada. Effects of riluzole on psychiatric disorders with anxiety or fear as primary symptoms: A systematic review. Neuropsychopharmacology reports. 2023
Yuko Nakatake, Hiroki Furuie, Mitsuhiko Yamada. [An emotional stress model using witnessing social defeat scenes in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2023. 158. 1. 39-42
Hiroshi Kuniishi, Mitsuhiko Yamada. [Subregion-dependent synaptic changes in the orbitofrontal-amygdala pathways by adolescent social isolation in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2023. 158. 1. 47-50
Momoko Kobayashi-Tanabe, Hiroki Furuie, Misa Yamada, Mitsuhiko Yamada. Characterization of a WD-repeat family protein WDR3 in the brain of WDR3 hetero knockout mice. Brain research. 2022. 1800. 148188-148188
Wu Y, Levis B, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Boruff J, Cuijpers P, Gilbody S, et al. Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis - ERRATUM. Psychological medicine. 2019. 50. 16. 1-2816
