Rchr
J-GLOBAL ID:200901083019998291   Update date: Sep. 27, 2024

Hagiwara Masatoshi

ハギワラ マサトシ | Hagiwara Masatoshi
Affiliation and department:
Homepage URL  (1): http://www.tmd.ac.jp/mri/mri-end/index.html
Research field  (2): Molecular biology ,  Molecular biochemistry
Research keywords  (6): 抗ウイルス薬 ,  SRPK ,  CREB ,  RNAプロセシング ,  ケミカルバイオロジー ,  Transcriptional Regulation
Research theme for competitive and other funds  (64):
  • 2021 - 2026 Synthetic investigation of pathological phase separation of RNA-binding proteins
  • 2015 - 2020 Therapeutic Drug Discovery and Elucidation of RNA Disease Pathogenesis by Use of CRISPR-Based Disease iPS Cells and Animal Models
  • 2016 - 2019 Drug screening system development for skeletal muscle diseases using human iPSC
  • 2015 - 2016 トランスクリプトームの人為的操作による遺伝病の治療
  • 2013 - 2016 Strategy for controlling intractable pain by targeting casein kinase 1 signaling system
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Papers (132):
  • Yuko Ohnishi, Atsushi Masui, Takahiro Suezawa, Ryuta Mikawa, Toyohiro Hirai, Masatoshi Hagiwara, Shimpei Gotoh. Screening of factors inducing alveolar type 1 epithelial cells using human pluripotent stem cells. Stem cell reports. 2024. 19. 4. 529-544
  • Mamiko Yamada, Kazuhiro Maeta, Hisato Suzuki, Ryo Kurosawa, Toshiki Takenouchi, Tomonari Awaya, Masahiko Ajiro, Atsuko Takeuchi, Hisahide Nishio, Masatoshi Hagiwara, et al. Successful skipping of abnormal pseudoexon by antisense oligonucleotides in vitro for a patient with beta-propeller protein-associated neurodegeneration. Scientific Reports. 2024. 14. 1
  • Ryo Kurosawa, Kei Iida, Masahiko Ajiro, Tomonari Awaya, Mamiko Yamada, Kenjiro Kosaki, Masatoshi Hagiwara. PDIVAS: Pathogenicity predictor for Deep-Intronic Variants causing Aberrant Splicing. BMC Genomics. 2023. 24. 1
  • Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Atsuko Hagiwara, Ryo Kurosawa, Yukiya Sako, Megumu Ogawa, Masashi Ogasawara, Satoru Noguchi, Yuichi Goto, et al. Branchpoints as potential targets of exon-skipping therapies for genetic disorders. Molecular therapy. Nucleic acids. 2023. 33. 404-412
  • Akiko Nakano-Kobayashi, Andres Canela, Toru Yoshihara, Masatoshi Hagiwara. Astrocyte-targeting therapy rescues cognitive impairment caused by neuroinflammation via the Nrf2 pathway. Proceedings of the National Academy of Sciences. 2023
more...
MISC (71):
  • 金光 瑛彰, 趙 向東, 祝迫 恵子, 八木 真太郎, 萩原 正敏. 外科医が行う臓器保存の研究とその副次的効果. 日本外科学会定期学術集会抄録集. 2021. 121回. SF-7
  • 豊本雅靖, 豊本雅靖, 栗原崇, 中川貴之, 井上飛鳥, 木村亮, 喜井勲, 喜井勲, 澤田照夫, 澤田照夫, et al. 非オピオイド鎮痛薬の創製. 鎮痛薬・オピオイドペプチドシンポジウムプログラム・抄録集. 2021. 40th
  • Ryo Kimura, Roy Lardenoije, Kiyotaka Tomiwa, Yasuko Funabiki, Masatoshi Nakata, Shiho Suzuki, Tomonari Awaya, Takeo Kato, Shin Okazaki, Toshiya Murai, et al. INTEGRATED EPIGENETIC ANALYSIS OF WILLIAMS SYNDROME. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019. 29. S242-S243
  • Arbones ML, Thomazeau A, Nakano-Kobayashi A, Hagiwara M, Delabar JM. DYRK1A and cognition: A lifelong relationship. Pharmacology & therapeutics. 2018. 194. 199-221
  • Kenji Ohe, Masatoshi Hagiwara. Modulation of Alternative Splicing with Chemical Compounds in New Therapeutics for Human Diseases. ACS CHEMICAL BIOLOGY. 2015. 10. 4. 914-924
more...
Professional career (1):
  • (BLANK)
Work history (1):
  • Tokyo Medical and Dental University Graduate School of Biomedical Science
Awards (1):
  • 1989 - 三医会賞
Association Membership(s) (6):
日本ケミカルバイオロジー研究会 ,  日本癌学会 ,  日本生化学会 ,  日本薬理学会 ,  日本解剖学会 ,  日本分子生物学会
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