Rchr
J-GLOBAL ID：200901083118282214   Update date: Mar. 10, 2023

AMAGASE KIKUKO

アマガセ キクコ | AMAGASE KIKUKO
Affiliation and department：
Ritsumeikan University College of Pharmaceutical Sciences Department of Pharmacy

About Ritsumeikan University College of Pharmaceutical Sciences Department of Pharmacy


Job title： Associate Professor
Homepage URL  (1)： http://www.ritsumei.ac.jp/ph/educators/detail.html/?id=62
Research field  (3)： Pharmacology ,  Pharmacology ,  Pharmacology
Research keywords  (7)： Helicobacter pylori ,  Inflammatory bowel disease ,  Drug-induced intestinal lesion ,  Peptic ulcer ,  Gastrointestinal inflammation ,  Gastrointestinal pharmacology ,  Gastrointestinal pharmacology, Gastrointestinal inflammation, Peptic ulcer, Drug-induced intestinal lesion, Inflammatory bowel disease, Helicobacter pylori
Research theme for competitive and other funds  (3)：
  • 2022 - 2024 難治性消化管疾患の病態解明と新たな治療戦略
  • 2018 - 2021 グルタミンおよびグルタミン酸の難治性消化管疾患の治療における応用
  • 2014 - 2017 グルタミン酸によるヘリコバクター・ピロリ関連胃病変の発生と定着抑制機序の解明
Papers (131)：
  • Kato D, Jonan S, Sugahara R, Otsuki H, Nakamura S, Amagase K. Efficacy of ginsenoside treatment to alleviate anticancer-drug induced mucoenteritis in mice. Integrative Physiology. 2022. 3. 539-546
  • Shizuka Jonan, Nahla Hamouda, Ayana Fujiwara, Kazumi Iwata, Takuya Fujita, Shinichi Kato and Kikuko Amagase. Alleviative effects of glutamate against chemotherapeutic agent-induced intestinal mucositis. Journal of Physiology and Pharmacology. 2022. 73. 4. 539-546
  • Bekhit AA, Nasralla SN, El-Agroudy EJ, Hamouda N, El-Fattah AA, Bekhit SA, Amagase K, Ibrahim TM. Investigation of the anti-inflammatory and analgesic activities of promising pyrazole derivative. Eur J Pharm Sci. 2022. 168. 106080
  • Mohamed MAA, Bekhit AA, Abd Allah OA, Kadry AM, Ibrahim TM, Bekhit SA, Amagase K, El-Saghier AMM. Synthesis and Antimicrobial Activity of Some Novel 1,2-Dihydro-[1,2,4] triazolo[1,5-a]pyrimidines Bearing Amino Acid Moiety. RSC Adv. 2021. 2905-2916
  • Aliaa Fouad, Kenjiro Matsumoto, Kikuko Amagase, Hiroyuki Yasuda, Makoto Tominaga, Shinichi Kato. Protective Effect of TRPM8 against Indomethacin-Induced Small Intestinal Injury via the Release of Calcitonin Gene-Related Peptide in Mice. Biological & pharmaceutical bulletin. 2021. 44. 7. 947-957
ｍore...
MISC (70)：
  • Takuya Tsukahara, Nahla Hamouda, Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Shinichi Kato. G Protein-Coupled Receptor 35 Signaling Promotes Mucosal Repair via Migration of Colonic Epithelial Cells in Mice. FASEB JOURNAL. 2017. 31
  • Kenjiro Matsumoto, Daichi Utsumi, Kikuko Amagase, Makoto Tominaga, Shinichi Kato. Transient receptor potential vanilloid 4 (TRPV4) regulates vascular endothelial permeability during colonic inflammation in dextran sulfate sodium-induced murine colitis. FASEB JOURNAL. 2017. 31
  • Shinichi Kato, Nahla Hamouda, Daichi Utsumi, Takuya Tsukahara, Kenjiro Matsumoto, Kikuko Amagase. Sequential Role of Apoptosis, Gram-negative Enterobacteria, and Inflammatory Cytokines in the Pathogenesis of 5-Fluorouracil-induced Intestinal Mucositis in Mice. FASEB JOURNAL. 2017. 31
  • Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Makoto Tominaga, Shinichi Kato. Potential Role of Transient Receptor Potential Ankyrin 1 (TRPA1) in Colonic Inflammation in Dextran Sulfate Sodium (DSS)-Induced Murine Colitis. GASTROENTEROLOGY. 2016. 150. 4. S52-S53
  • Takuya Tsukahara, Nahla Hamouda, Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Shinichi Kato. G Protein-Coupled Receptor 35 (GPR35) Contributes to Mucosal Healing in Mouse Colonic Epithelial Cells. GASTROENTEROLOGY. 2016. 150. 4. S490-S490
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Patents (2)：
  • 消化管疾患の予防及び/又は治療剤
  • 5-フルオロウラシル誘発性腸疾患の予防及び/又は治療剤
Books (31)：
  • 図解 薬害・副作用学 改訂3版. 川西正祐、小野秀樹、賀川義之編集. 「3章 薬剤による副作用 8.消化器系に作用する薬物」
    2023
  • 新しい疾患薬理学 改訂第2版. 岩崎克典、徳山尚吾 編集. 「6章 消化器内科領域の疾患に用いる薬物」
    南江堂 2022
  • 認知症plus予防教育 「第3章生活習慣病予防 ベクトル2-薬についての健康教育」
    日本看護協会出版会 2020
  • シンプル薬理学 改訂第6版 「第12章消化器系作用薬」
    南江堂 2020
  • 疾患薬理学,岩崎克典、徳山尚吾 編集. 「6章:呼吸器系・消化器系の疾患と治療薬」
    南江堂 2018
ｍore...
Lectures and oral presentations  (14)：
  • グルタミン酸の5-フルオロウラシル誘起腸炎に対する保護作用
    (第49回日本潰瘍学会 2022)
  • New Therapeutic Strategy for Amino Acid: Prophylactic and Therapeutic Effect of Monosodium Glutamate against Gastrointestinal Inflammation
    (American Gastroenterological Association 2020 2020)
  • 腸粘膜傷害の修復・治癒におけるロイコトリエン受容体タイプ2(BLT2)の役割
    (第47回日本潰瘍学会 2020)
  • 5-フルオロウラシル誘起腸炎の病態におけるアポトーシス、腸内細菌叢の異常および炎症性サイトカインの役割
    (医療薬学フォーラム2018 2018)
  • Cyclooxygenase isozymes and prostaglandins as well as their receptors involved in modulating gastric mucosal integrity under stress conditions
    (Summer School on Stress 2018 2018)
ｍore...
Education (3)：
  • - 1995 Kyoto Pharmaceutical University Graduate School Graduate School of Pharmaceutical Sciences Course of Pharmacy
  • - 1995 Kyoto Pharmaceutical University Graduate School Graduate School of Pharmaceutical Sciences Course of Pharmacy
  • - 1993 Kyoto Pharmaceutical University Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
  • Ph.D (Kyoto Pharmaceutical University Graduate School)
Work history (5)：
  • 2018/04 - Ritsumeikan University, College of Pharmaceutical Sciences Associate Professor
  • 2018/04 - Kyoto Pharmaceutical University, Professor
  • 2013/10 - 2018/03 Kyoto Pharmaceutical University, Lecturer
  • 2007/04 - 2013/09 Kyoto Pharmaceutical University, Assistant Professor
  • 1995/04 - 2007/03 Kyoto Pharmaceutical University, Research Assistant
Committee career (19)：
  • 2019/02 - The Pharmaceutical Society of Japan Young coordinator of Division of Pharmacology & Drug Therapeutics
  • 2019/02 - 日本薬学会 代議員
  • 2018/10 - The Japanese Pharmacological Society representative
  • 2018/10 - 日本薬理学会 代議員
  • 2018/08 - 滋賀県 健康医療福祉部
Show all
Awards (4)：
  • 2015/08 - 日本薬学会 平成26年度日本薬学会 薬理系薬学部会 奨励賞
  • 2013/03 - 日本サイトプロテクション研究会 第31回日本Cytoprotection研究会 奨励賞
  • 2012/07 - 日本潰瘍学会 第40回日本潰瘍学会 奨励賞
  • 2010/05 - American Gastroenterological Association 米国消化器病学会2010 ベストポスター賞
Association Membership(s) (13)：
米国生理学会 ,  日本癌学会 ,  日本薬剤師会 ,  International Union of Basic and Clinical Pharmacology ,  American Gastroenterological Association ,  Japanese Society for Cytoprotection & Cytobiology ,  Japan Osteoprosis Society ,  The Japanese Society for Bone and Mineral Research ,  The Japanese Society of Clinical Pharmacology and Therapeutics ,  The Japanese Gastroenterological Association ,  The Japanese Society of Ulcer Research ,  The Japanese Pharmacological Society ,  The Pharmaceutical Society of Japan
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