Rchr
J-GLOBAL ID：200901083841867379
Update date: Apr. 30, 2024
Mohri Satoshi
Mohri Satoshi
Affiliation and department：
Research field (1)：
Physiology
Research theme for competitive and other funds (47)：
- 2014 - 現在 心臓のマクロ機能と遺伝子発現連関のための情報制御:酸素環境応答のフィジオーム解析
- 2014 - 現在 多階層医工学的解析に基づく心臓の機械受容システムの分子基盤と生理的意義の解明
- 2013 - 現在 心筋細胞分化制御メカニズムのフィジオーム解析
- 2013 - 現在 単球の血管内皮下浸潤における機械刺激感受性分子TRPV2の役割と動脈硬化との関連
- 2021 - 2025 哺乳類心筋細胞のT管膜構造の維持機構の解明と進化的意義の探求
- 2022 - 2024 冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出
- 2021 - 2024 A paradigm shift in fetal oxygen regulation implicated in heart regeneration.
- 2020 - 2024 Creation of innovative myocardial regeneration strategy with soft and highly dividing cardiomyocytes
- 2020 - 2023 運動と循環の起源と進化:新たな指標による地球環境変遷との関連解明
- 2020 - 2023 心筋細胞の張力伝達ネットワークによる機械受容機構解明と心不全治療への展開
- 2019 - 2023 哺乳類と異なる戦略で優れた心機能を発揮する鳥類に学ぶ革新的心不全治療の創出
- 2019 - 2022 Super-resolution oxygen partial pressure imaging of single cells
- 2017 - 2022 胎児循環における物質輸送特性の再評価と胎児心血管系制御システムの解明
- 2018 - 2021 A novel approach to myocardial regeneration based on hypoxia-dependent, multi-hierarchical intrauterine environment.
- 2017 - 2021 バネ分子コネクチンによる心臓メカニクス制御機構解明と心不全治療への展開
- 2017 - 2020 Preliminary study for cardiac regeneration using novel cell cycle promoter Fam64a
- 2016 - 2019 Elucidation of the mechanosensing function in heart by a muscle elastic protein connectin
- 2014 - 2017 The importance of local Ca2+ control beneathe the T-tubule membrane in cardiomyocytes
- 2014 - 2016 The maintenance of cardiac structure and function by mechanical feedback system involving multiple organ systems.
- 2011 - 2014 心機能制御における心肥大・心室形態調節の分子基盤と臓器機能連関のフィジオーム解析
- 2011 - 2012 Development of visualization of soft tissue morphology and protein concentration by X-ray phase-contrast computed tomography.
- 2010 - 2012 Elucidation of Biological Adaptation and Remodeling Mechanisms to Mechanical Stress Based on the Development of Novel Micro-Electro-Mechanical Systems (MEMS) technology
- 2009 - 2011 マルチレベル医工学評価法に基づく心筋メカノセンサーの作動機序と病態生理的役割
- 2009 - 2010 医工学的解析に基づく肺ストレッチセンサーを介した肺がん発症機構の解明
- 2008 - 2010 Role of mechanical load in human myocardial excitation contraction coupling
- 2008 - 2010 冠循環・心臓メカニクス連関:分子進化から心機能、心不全発症機構までの医工学的解析
- 2007 - 2009 The role of mechanosensor on cardiovascular disease.
- 2005 - 2009 Application of Soft Lithography to Mechanobiology
- 2007 - 2008 Novel mechanism of abnormal intracellular Ca2+ handling in heart failure
- 2007 - 2008 未熟児網膜症におけるヘモグロビン変換の関与
- 2007 - 2008 生体血管膜モデルを用いた血管新生・消退機構の統合的解析
- 2007 - 2008 プレコンディショニング運動の毛細血管ネットワークと骨格筋細胞のクロストーク研究
- 2005 - 2008 Promotion of cardiovascular physiome focusing on coronary microcirculation and myocardial crossbridge dynamics
- 2006 - 2007 心筋特異的非ウイルス性遺伝子ベクターの開発および心筋細胞との相互作用評価
- 2005 - 2007 Pathophysiological analysis of myocardial dysfunction by observing nanometer ordernanometer-order dynamics of actin-myosin, interaction
- 2005 - 2007 Investigation of vascular resistance reducing therapy for primary pulmonary hypertension: replacement of RBC with nano-order liposomal hemoglobin
- 2005 - 2006 水晶体発育期のクリスタリン構造調節因子:SPring-8X線回折による統合的解析
- 2003 - 2004 新生ラットにおける冠微小循環系と心筋の相互依存性増殖過程の医工学的解析
- 2003 - 2004 可逆性完全不死化心筋細胞株の樹立およびナノオーダー機能評価
- 2003 - 2004 医工学的再構築心筋組織の作成およびナノオーダー機能評価
- 2002 - 2004 Analyses of transmural difference of myocardial crossbridge dynamics using SPring-8 synchrotron facility
- 2001 - 2004 Analysis of coronary microcirculation and myocardial crossbridge dynamic using SPring-8 synchrotron facility
- 2001 - 2002 病態モデル小動物における腎糸球体微小循環可視化法の開発と病態生理学的解析
- 1998 - 1999 統合生理学的分析法による心臓内カルシウム無駄サイクル数の推定法
- 1998 - 1999 陰性変時作用を持つ新しいカルシウムセンシタイザーEGIS-9377の生理学的特性
- 1998 - 1999 Assessment of the total amount of CAィイD12+ィエD1 handled in the E-C coupling by analyzing postextrasystolic potentiation and OィイD22ィエD2 consumption : Systems approach
- 1997 - 1999 Macro-micro correspondence in mechanoenagetics of failing hearts
Show all
Papers (103)：
-
Yuu Usui, Akira Hanashima, Ken Hashimoto, Misaki Kimoto, Momoko Ohira, Satoshi Mohri. Comparative analysis of ventricular stiffness across species. Physiological Reports. 2024. 12. 8
-
Kehao Wang, Yutian Pu, Leran Chen, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Xiaoyong Chen, Yuu Usui, Akira Hanashima, Ken Hashimoto, et al. Optical development in the murine eye lens of accelerated senescence-prone SAMP8 and senescence-resistant SAMR1 strains. Experimental eye research. 2024. 241. 109858-109858
-
Yuu Usui, Misaki Kimoto, Akira Hanashima, Ken Hashimoto, Satoshi Mohri. Cardiac hemodynamics and ventricular stiffness of sea-run cherry salmon (Oncorhynchus masou masou) differ critically from those of landlocked masu salmon. PLOS ONE. 2022. 17. 11. e0267264-e0267264
-
Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shun Nagashima, Isshin Shiiba, Naoki Ito, Taku Amo, Satoshi Mohri, et al. Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. 2022. 25. 7. 104582-104582
-
Ken Hashimoto, Aya Kodama, Momoko Ohira, Misaki Kimoto, Reiko Nakagawa, Yuu Usui, Yoshihiro Ujihara, Akira Hanashima, Satoshi Mohri. Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15. iScience. 2022. 25. 5. 104337-104337
ｍore...
MISC (32)：
-
Yuki Katanosaka, Makoto Shibuya, Yoshihiro Ujihara, Satoshi Mohri, Keiji Naruse. TRPV2 is Crucial for the Development of Intercalated Discs in Mouse Hearts. BIOPHYSICAL JOURNAL. 2019. 116. 3. 538A-538A
-
Yuki Katanosaka, Yoshihiro Ujihara, Yumiko Chiba, Satoshi Mohri, Keiji Naruse. TRPV2 is Crucial for the Development of Excitation-Contraction Coupling in Neonatal Cardiomyocytes. BIOPHYSICAL JOURNAL. 2018. 114. 3. 484A-484A
-
Yoshihiro Ujihara, Satomi Takatsu, Keiji Naruse, Satoshi Mohri, Yuki Katanosaka. The Role of NCX1 on the Maintenance of T-Tubule Architecture in Pressure-Overloaded Hearts. BIOPHYSICAL JOURNAL. 2018. 114. 3. 619A-619A
-
UJIHARA Yoshihiro, HASHIMOTO Ken, MOHRI Satoshi, KATANOSAKA Yuki. 1D42 Mechanical signaling via TRPV2 in cardiomyocytes. 2016. 2016. 28. "1D42-1"-"1D42-4"
-
Ken Hashimoto, Yoshihiro Ujihara, Satoshi Mohri. Preliminary analysis of differentiation and proliferation program of cardiomyocytes in developmental stages. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S120-S120
ｍore...
Patents (2)：
-
pHの測定装置及び測定方法
-
pHまたは濃度の測定装置及びpHまたは濃度の測定方法
Books (1)：
-
冠循環系の生理学 冠循環フィジオーム Physiome in coronary circulation-links between function and structure, organ and molecule, and hopefully past and future-「日本臨床 冠動脈疾患」
日本臨牀社 2011
Lectures and oral presentations (92)：
-
軟骨魚類心臓の構造と弾性蛋白質コネクチンの独自進化
(日本進化学会第20回大会 2018)
-
心室における筋弾性蛋白質コネクチンの脊椎動物種間比較と生理学・進化的意義
(第4回日本筋学会学術大会 2018)
-
Extension restriction of coronary circulation hearts by shortening of the elastic protein connectin
(第57回日本生体医工学会大会 2018)
-
Comparative study of tensile properties of ventricular cardiomyocytes of rat and turtle
(2018)
-
コネクチンnovex-3 は低酸素下の胎児期心筋細胞の分裂を促進する
(第57回日本生体医工学会大会 2018)
ｍore...
Education (1)：
- 1986 - 1992 Okayama University Faculty of Medicine
Work history (1)：
Committee career (1)：
Association Membership(s) (3)：
Society of Evolutionary Studies, Japan
, 日本生理学会
, 日本生体医工学会
