Rchr
J-GLOBAL ID：200901083888817485   Update date: Feb. 22, 2024

Matsuoka Isao

マツオカ イサオ | Matsuoka Isao
Affiliation and department：
Takasaki University of Health and Welfare

About Takasaki University of Health and Welfare


Research field  (3)： Neuroscience - general ,  Pharmacology ,  Immunology
Research keywords  (13)： 青斑核神経 ,  薬物依存 ,  脳内分布 ,  神経薬理学 ,  eicosanoides ,  ecto-nucleotidase ,  P2 receptors ,  ATP ,  platelets ,  mast cells ,  macrophage ,  vascular endothelial cells ,  inflammation
Research theme for competitive and other funds  (18)：
  • 2019 - 2022 Establishment of therapeutic basis for allergic diseases targeting P2X4 receptor of mast cells
  • 2015 - 2016 運動トレーニングによるプリン作動性シグナルの亢進と健康増進作用との関連について
  • 2008 - 2010 ATP分解酵素CD39を標的とした新規血管内皮細胞保護薬の開発に向けた 基礎的研究
  • 2008 - 2009 Novel mechanism for regulation of inflammatory response.
  • 2008 - 2009 低分子量G蛋白質の活性調節におけるイソプレニル化酵素の役割
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Papers (112)：
  • Yoshinobu Nakamura, Masa-aki Ito, Yukino Hoshino, Isao Matsuoka, Toshiaki Okada, Yasunobu Okada, Takeo Nakanishi. Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10. American Journal of Physiology-Cell Physiology. 2024
  • Kazuki Yoshida, Masa-aki Ito, Isao Matsuoka. P2X4受容体を介したATPによるマスト細胞の活性化の増強. Folia Pharmacologica Japonica. 2024. 159. 1. 39-43
  • Norikazu Okuma, Masa-aki Ito, Tomoyoshi Shimizu, Atsuya Hasegawa, Shin’ya Ohmori, Kazuki Yoshida, Isao Matsuoka. Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ. Scientific Reports. 2023. 13. 1
  • Noriyuki Yamagiwa, Mika Komine, Fumi Hanaoka, Tomoya Nobuta, Kazuki Yoshida, Masaaki Ito, Isao Matsuoka. Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity. Bioorganic & Medicinal Chemistry Letters. 2022. 77. 129035-129035
  • Kazuki Yoshida, Shota Tanihara, Yuki Miyashita, Kosuke Obayashi, Masa-aki Ito, Kimiko Yamamoto, Toshiyashu Imai, Isao Matsuoka. P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice. Scientific Reports. 2022. 12. 1
ｍore...
MISC (90)：
  • 吉田一貴, 谷原祥太, 宮下友希, 大林晃右, 伊藤政明, 松岡功. P2X4 receptor signaling enhanced psuedallergyc response. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 青木楓佳, 伊藤政明, 吉田一貴, 松岡功. Analysis of ATP-induced enhancement of interleukin 6 production in human glioblastoma. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 秋吉玲未乃, 伊藤政明, 吉田一貴, 松岡功. Evaluation of mesenteric artery function in LPS-induced sepsis model mice. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 大林昂右, 吉田一貴, 伊藤政明, 松岡功. Analysis of synergistic cytokine production induced by co-stimulation of ATP and PGE2 in mast cells. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 大熊範和, 大熊範和, 伊藤政明, 吉田一貴, 松岡功. Synergistic effects of IFN-γ and poly(I:C) on cytokine production in human airway epithelial NCl-H292 cells. 日本薬学会年会要旨集(Web). 2022. 142nd
ｍore...
Education (2)：
  • 1978 - 1981 Hokkaido University Faculty of Pharmaceutical Sciences Department of Pharmacy
  • - 1981 Hokkaido University Faculty of Pharmaceutical Science
Professional career (1)：
  • 薬学博士 (東京大学)
Work history (4)：
  • 2006/04 - 現在 Takasaki University of Health and Welfare Faculty of Pharmacy Professor
  • 1999/08 - 2006/03 Fukusima Medical University School of Medicine Associate professor
  • 1981/04 - 1999/08 Fukusima Medical University School of Medicine Research Assistant
  • 1991/01 - 1993/01 フランス国立保健医学研究所(INSERM) U-99 外国人研究員
Awards (1)：
  • 2002 - 福島医学会 学術奨励賞
Association Membership(s) (6)：
FUKUSHIMA MEDICAL SOCIETY ,  Japanese Association of Cardiovascular Pharmacology ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本薬理学会 ,  日本生化学会
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