Narita Akihiro

Narita Akihiro | Narita Akihiro

Affiliation and department：
Job title： Associate professor
Homepage URL (1)： http://str.bio.nagoya-u.ac.jp:8080/Plone/524d753030eb30fc/30e130f330fc/6210753054f2535a

Research field (1)： Bio-, chemical, and soft-matter physics

Research keywords (3)：電子顕微鏡による三次元構造決定 , 微小管等の細胞骨格に関する蛋白質複合体の , Structure determination of cytoskeletal protein complexes by electron microscopy

Research theme for competitive and other funds (11)：

2022 - 2027 Simplifying complexity and diversity of circadian clocks
2021 - 2024 Direct observation of biomolecular dynamics by a pulsed electron microscope
2019 - 2022 Semiconductor electron beam source that brings fine-area dynamics observation technology to damage sensitive samples
2019 - 2021 Development of liquid chamber for pulsed electron microscopy
2018 - 2021 Understanding dynamics of the actin filament using cryoEM and structural determination from a small number of images

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Papers (90)：

Kaoru Okura, Tomoharu Matsumoto, Akihiro Narita, Hitoshi Tatsumi. Mechanical Stress Decreases the Amplitude of Twisting and Bending Fluctuations of Actin Filaments. Journal of Molecular Biology. 2023. 435. 22. 168295-168295
Yusuke Kanematsu, Akihiro Narita, Toshiro Oda, Ryotaro Koike, Motonori Ota, Yu Takano, Kei Moritsugu, Ikuko Fujiwara, Kotaro Tanaka, Hideyuki Komatsu, et al. Structures and mechanisms of actin ATP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 43. e2122641119
Daichi Takahashi, Ikuko Fujiwara, Yuya Sasajima, Akihiro Narita, Katsumi Imada, Makoto Miyata. ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming. Open Biology. 2022. 12. 10
Caner Akıl, Samson Ali, Linh T Tran, Jérémie Gaillard, Wenfei Li, Kenichi Hayashida, Mika Hirose, Takayuki Kato, Atsunori Oshima, Kosuke Fujishima, et al. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Science advances. 2022. 8. 12. eabm2225
Jiro Usukura, Akihiro Narita, Tomoharu Matsumoto, Eiji Usukura, Takeshi Sunaoshi, Syunya Watanabe, Yusuke Tamba, Yasuhira Nagakubo, Takashi Mizuo, Junzo Azuma, et al. A cryo-TSEM with temperature cycling capability allows deep sublimation of ice to uncover fine structures in thick cells. Scientific Reports. 2021. 11. 1

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MISC (13)：

武田修一, 兼松佑典, 成田哲博, 田中康太郎, 小池亮太郎, 太田元規, 鷹野優, 森次圭, 藤原郁子, 渡邉信久, et al. F-form actin structure at an atomic resolution: how the molecular assembly and the ATP hydrolysis are coupled. 日本物理学会講演概要集(CD-ROM). 2020. 75. 1
武田修一, 藤原郁子, 小田俊郎, 成田哲博, 前田雄一郎. ラトランキュリンAはF型からG型へのコンフォメーション変化を誘起しアクチン脱重合を促進する. 日本結晶学会年会講演要旨集. 2019. 2019
武田修一, 成田哲博, 小田俊郎, 田中康太郎, 小池亮太郎, 太田元規, 藤原郁子, 渡邉信久, 渡邉信久, 前田雄一郎. 高分解能X線結晶構造から明らかとなったアクチン重合・ATP加水分解機構. 日本結晶学会年会講演要旨集. 2017. 2017
E. Usukura, A. Narita, A. Yagi, S. Ito, J. Usukura. Atomic force microscopic (AFM) imaging of cytoskeleton in retinal photoreceptor cells in cryosection. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
J. Usukura, E. Usukura, T. Matsumoto, A. Narita. Development of low voltage cryo-electron microscope for simultaneous imaging of bright field, dark field STEM and SEM using unroofed frozen cells. MOLECULAR BIOLOGY OF THE CELL. 2015. 26

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Lectures and oral presentations (6)：

A new image analysis to determine the dynein-microtuble complex structure
(BIOPHYSICAL JOURNAL 2007)
Cryo-EM study of dynein-microtubule complex
(BIOPHYSICAL JOURNAL 2007)
Three-dimensional reconstruction of thin filaments by energy filtered electron cryo-microscopy.
(Seibutsu Butsuri 2001)
A new method of image analysis to visualize troponin structure in thin filaments
(Seibutsu Butsuri 2000)
A 3 dimensional structural analysis of thin filament without helical symmetry
(Biophysics 1997)

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Works (1)：

Education (3)：

Professional career (2)：

Work history (7)：

2013/04/01 - 現在 Nagoya University Graduate School of Science Division of Biological Science Supramolecular Biology Associate professor
2012 - 2015 Japan Science and Technology Agency
2007/11/01 - 2013/03/31 Nagoya University Graduate School of Science Structural Biology Research Center Assistant Professor
2005 - 2007 Japan Science and Technology Agency
2002 - 2005 RIKEN

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Committee career (9)：

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Awards (4)：

2019 - Distinguished Paper Award. Direct observation of the actin filament by tip-scan atomic force microscopy
2018 - Distinguished Paper Award. A new approach for the direct visualization of the membrane cytoskeleton in cryo-electron microscopy: a comparative study with freeze-etching electron microscopy
2008 - 文部科学省文部科学大臣表彰若手科学賞電子顕微鏡によるアクチンフィラメント端複合体構造の研究
2007 - 風戸研究奨励会風戸研究奨励賞 ATP状態アクチンフィラメントの高分解能構造決定

Association Membership(s) (2)：

The biophysical society of Japan , The Japanese Society of Microscopy

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