Shimosawa Tatsuo

2019 - 2022 Influence of cardiovascular function on intermittent hypoxia in rat fed high-fat diet

2017 - 2019 Salt-sensitive hypertension and vascular dysfunction

2015 - 2019 Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction

2014 - 2018 THE MECHANISM OF SALT SENSITIVE HYPERTENSION IN INTERMITTENT HYPOXIA

2016 - 2017 心腎連関における炎症とキニン系、アンジオテンシン系の役割

2014 - 2016 Epigenetical regulation in cardiorenal syndrome by sympathetic nerve activity

2011 - 2016 生活習慣病による進行性腎障害に関わるエピジェネティック異常の解明と診断・治療への応用

2012 - 2014 Protective effect for antioxidative peptide against disruption of blood brain barrier induced ischemic injury

2011 - 2013 Mechanisms and diagnosis of salt-sensitive hypertension in view point of epigenetics

2011 - 2013 Investigation of cardio-pulmonary disorder in the animal model of sleep apnea syndrome

2009 - 2011 Insulin resistance and protective role for antioxidative peptide in ischemic white matter damages

2008 - 2010 メタボリックシンドロームとNASHの発症

2008 - 2010 食塩感受性高血圧

2008 - 2010 Pathophysiological mechanisms and therapeutic targets in multiple organ damages in metabolic syndrome

2008 - 2010 Clarification of the mechanism of metabolic and vascular regulation by RAMP and its application in metabolic disorders and vascular injuries.

2006 - 2007 Therapeutic potency of platinum nanoparticle in metabolic syndrome

2006 - 2007 Production and characterization of Adrenomedullin (-/-)<->(+/+) and RAMP2(-/-)<-> (+/+) chimeric mice

2005 - 2007 Targeting oxidative stress and new therapy in metabolic syndrome

2004 - 2005 Therapeutic potency of antioxidative peptide in metabolic syndrome

2002 - 2003 Role of LOX-1 and protective effect of PPARγ in the development of atherosclerosis

2002 - 2003 遺伝子工学を用いた動脈硬化形成とその防御機構の解析-LOX-1とPPARγの役割

2001 - 2003 Organ protective effect of adrenomedullin, studies using knockout mice.

2000 - 2002 Role of oxidized LDL/LOX-1 in the development and progression of renal disease.

1998 - 2002 PHYSIOLOGICAL ROLE OF ADRENOMEDULLIN BY MOLECULAR BIOLOGICAL AND GENE ENGINEERING APPROACH

2000 - 2001 発生工学を用いた食塩感受性高血圧発症機序及び臓器障害進展の研究

1999 - 2000 プロアドレノメデュリンN末端20ペプチド(PAMP)の交感神経系に与える影響、慢性及び内因性PAMPの効果

1998 - 1999 Regulation of vascular p38 mitogen-activated protein kinase and its role in the vascular function

1991 - 1993 Multiple mechanisms for vasodilator effect of magnesium

Renal hemodynamic change and aging

Senile marker protein30 (SMP30) and its physiological role

Physiology hypotensive peptides