Rchr
J-GLOBAL ID：200901084346128906   Update date: Sep. 28, 2024

Masato Tanaka

タナカ マサト | Masato Tanaka
Affiliation and department：
Tokyo University of Pharmacy and Life Sciences Yokohama Institute, Research Center for Allergy and Immunology

About Tokyo University of Pharmacy and Life Sciences Yokohama Institute, Research Center for Allergy and Immunology


Research field  (1)： Immunology
Research keywords  (2)： Macrophage ,  Cell death
Research theme for competitive and other funds  (13)：
  • 2021 - 2026 Chemical Challenge for Elucidation of the Molecular Mechanism of Lipid Peroxidation-mediated Necrosis
  • 2021 - 2024 炎症によるがん転移促進の核心を担う制御性単球の機能
  • 2020 - 2023 Mechanisms of tissue repair by immnuoregulatory monocytes
  • 2013 - 2016 Functional analysis of tumor-associated macrophages accumulating in dead tumor cells
  • 2008 - 2009 死細胞処理による末梢性自己免疫寛容誘導機構の解明
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Papers (113)：
  • Ayaka Iwata, Juri Maruyama, Shibata Natsuki, Akira Nishiyama, Tomohiko Tamura, Minoru Tanaka, Shigeyuki Shichino, Takao Seki, Toshihiko Komai, Tomohisa Okamura, et al. Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice. Communications biology. 2024. 7. 1. 681-681
  • Kenichi Asano, Kenta Kikuchi, Miki Takehara, Manami Ogasawara, Yuki Yoshioka, Kie Ohnishi, Ayaka Iwata, Shigeomi Shimizu, Masato Tanaka. Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity. Biochemical and Biophysical Research Communications. 2023. 684. 149135-149135
  • Abigail K. Grootveld, Wunna Kyaw, Veera Panova, Angelica W.Y. Lau, Emily Ashwin, Guillaume Seuzaret, Rama Dhenni, Nayan Deger Bhattacharyya, Weng Hua Khoo, Maté Biro, et al. Apoptotic cell fragments locally activate tingible body macrophages in the germinal center. Cell. 2023. 186. 6. 1144-1161.e18
  • Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, et al. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell reports. 2023. 42. 3. 112165-112165
  • Chihiro Kurematsu, Masato Sawada, Masaki Ohmuraya, Motoki Tanaka, Kazuya Kuboyama, Takashi Ogino, Mami Matsumoto, Hisashi Oishi, Hiroyuki Inada, Yuri Ishido, et al. Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine. The Journal of experimental medicine. 2022. 219. 4
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MISC (18)：
  • 室井惟知, 四元聡志, 千葉達矢, 大村里緒, 曲澤恵, 米山真紀, てんてん孝介, 寺山直樹, 袖岡幹子, 青柳良平, et al. 薬剤性ネトーシスの誘導機構. 日本Cell Death学会学術集会プログラム抄録集. 2017. 26th
  • Philip E. Boulais, Nico van Rooijen, Masato Tanaka, Paul S. Frenette. F4/80 Identifies a Subset of Non-Mobilizable Bone Marrow HSCs Involved in Stress-Induced Hematopoiesis. BLOOD. 2016. 128. 22
  • 朴 雪花, 山崎 創, 駒澤 幸子, 近, 三宅 早苗, 中林 修, 田中 稔, 大村谷 昌樹, 及川 彰, 角田 宗一郎, et al. 細胞死制御因子cFLIPの肝細胞特異的欠損マウスを用いた肝障害モデルにおけるクッパー細胞および骨髄由来細胞の役割. 日本生化学会大会プログラム・講演要旨集. 2016. 89回. [2T05-05(2P
  • 朴 雪花, 山崎 創, 駒澤 幸子, 近, 三宅 早苗, 中林 修, 田中 稔, 大村谷 昌樹, 及川 彰, 角田 宗一郎, et al. 細胞死制御因子cFLIPの肝細胞特異的欠損マウスを用いた肝障害モデルにおけるクッパー細胞および骨髄由来細胞の役割. 日本生化学会大会プログラム・講演要旨集. 2016. 89回. [2P-033(2T05
  • Immune Regulation by Tissue Resident CD169-positive Macrophages. 2014. 33. 12. 1261-1266
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Lectures and oral presentations  (10)：
  • 制御性単球による免疫制御
    (第23回Pharnaco-Hematolayシンポジウム 2023)
  • 緊急造血における好中球様単球の分化経路の解明
    (第95回日本生化学会大会 2022)
  • 組織傷害に伴う炎症抑制型単球の増産とその生理的意義
    (第95回日本生化学会大会 2022)
  • 脂質酸化依存的ネトーシスの誘導機構
    (第94回日本生化学会大会 2021)
  • 新しい単球サブセットによるがん転移促進とその機構
    (第65回日本薬学会関東支部会 2021)
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Education (2)：
  • 1991 - 1995 Tokyo Medical and Dental University
  • 1982 - 1988 Tokyo Medical and Dental University
Professional career (1)：
  • 医学博士 (東京医科歯科大学)
Work history (11)：
  • 2011/04 - 現在 Tokyo University of Pharmacy and Life Sciences Laboratory of Immune Regulation School of Life Sciences Professor
  • 2002/08 - 2011/03 RIKEN Research Center Team Leader
  • 2000/01 - 2004/03 Osaka University Medical School the Department of Genetics Assistant Professor
  • 1999/08 - 1999/12 Osaka University Medical School The Department of Genetics Research Associate
  • 1997/09 - 1999/07 Tularik Inc. postdoctoral fellow
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Committee career (3)：
  • 2017/10 - 現在 マクロファージ分子細胞生物学研究会 幹事
  • 2015/07 - 現在 日本CellDeath学会 理事
  • 2014 - 現在 日本免疫学会 評議委員
Association Membership(s) (5)：
The Japanese Society for Cell Death Research ,  International Symposium on Molecular Cell Biology of Macrophages ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE BIOCHEMICAL SOCIETY
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