Rchr
J-GLOBAL ID:200901084513531670   Update date: Jan. 30, 2024

Hayashi Hideki

林 日出喜 | Hayashi Hideki
Affiliation and department:
Job title: Associate Professor
Research field  (1): Virology
Research keywords  (6): gene expression ,  protease ,  influenza virus ,  interferon ,  gene editing ,  Molecular biology
Research theme for competitive and other funds  (39):
  • 2020 - 2021 COVID-19に対するワクチンの開発
  • 2016 - 2019 自己削除型レンチウイルスベクターによる遺伝子治療法の開発
  • 2012 - 2015 インターフェロン調節因子のトリプシノーゲン遺伝子等を介したウイルス感染防御機構
  • 2012 - 2015 ウイルスハンティングに有用なインターフェロン伝達因子阻害細胞株の樹立
  • 2010 - 2014 The mechanism of transcriptional regulation of Runx2 gene and the program of skeletal development
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Papers (91):
  • Naoya Murayama, Takafumi Miyaki, Daisuke Okuzaki, Yasuaki Shibata, Takehiko Koji, Asuka Inoue, Junken Aoki, Hideki Hayashi, Yoshimasa Tanaka, Hiroyuki Murota. Transcriptome Profiling of Anhidrotic Eccrine Sweat Glands Reveals that Olfactory Receptors on Eccrine Sweat Glands Regulate Perspiration in a Ligand-Dependent Manner. JID Innovations. 2023. 3. 4. 100196-100196
  • Yoshinao Kubo, Kiyoshi Yasui, Mai Izumida, Hideki Hayashi, Toshifumi Matsuyama. IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of γ-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement. Cells. 2022. 11. 14. 2240-2240
  • Mai Izumida, Osamu Kotani, Hideki Hayashi, Chris Smith, Tsutomu Fukuda, Koushirou Suga, Masatomo Iwao, Fumito Ishibashi, Hironori Sato, Yoshinao Kubo. Unique Mode of Antiviral Action of a Marine Alkaloid against Ebola Virus and SARS-CoV-2. Viruses. 2022. 14. 4
  • Mai Izumida, Hideki Hayashi, Chris Smith, Fumito Ishibashi, Koushirou Suga, Yoshinao Kubo. Antivirus activity, but not thiolreductase activity, is conserved in interferon-gamma-inducible GILT protein in arthropod. Molecular Immunology. 2021. 140. 240-249
  • Ko Sato, Hideki Hayashi, Yoshitaka Shimotai, Mutsuo Yamaya, Seiji Hongo, Kazuyoshi Kawakami, Yoko Matsuzaki, Hidekazu Nishimura. TMPRSS2 activates hemagglutinin-esterase glycoprotein of influenza C virus. Journal of virology. 2021. JVI0129621
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MISC (3):
  • UEZONO Yasuhito, KAIBARA Muneshige, HAYASHI Hideki, TANIYAMA Kohtaro. Enteric nervous system in gastointestinal motility. 2003. 40. 2. 116-121
  • M Kaibara, K Ishihara, Y Doi, H Hayashi, T Ehara, K Taniyama. A critical amino acid residue affecting trafficking of inward rectifier potassium channel, Kir2.1 and Kir2.2. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2003. 91. 245P-245P
  • 大西 哲生, 林 日出喜, 王 立宏, 蛯名 洋介. P13-キナーゼ下流因子Aktのインスリンシグナル伝達における役割. 日本分子生物学会年会プログラム・講演要旨集. 1996. 19. 158-158
Patents (1):
  • ウイルスベクターによるcas9遺伝子の部位特異的的導入方法
Books (4):
  • Targets in Gene Therapy (edited by Prof. Yongping You) - Chapter (Effective transgene constructs to enhance gene therapy with trichostatin A)
    InTech 2011
  • Targets in Gene Therapy (edited by Prof. Yongping You) - Chapter (Effective transgene constructs to enhance gene therapy with trichostatin A)
    InTech 2011
  • Insulin Receptor.
    Advances in cell and molecular biology of membranes and organelles Vol3 1994/Signal transduction through growth factor receptors 1994
  • Insulin Receptor.
    Advances in cell and molecular biology of membranes and organelles Vol3 1994/Signal transduction through growth factor receptors 1994
Lectures and oral presentations  (3):
  • 酵母細胞を使ったアポトーシスの研究
    (第18回日本アポトーシス研究会 学術集会 (日本Cell Death学会設立記念学術集会) 2009)
  • Search for Anti-inflammatory molecules
    (Nagasaki-Singapore Symposium 2008)
  • Search for Anti-inflammatory molecules
    (2008)
Works (5):
  • シグナル伝達因子活性化を指標とした創薬の基礎研究
    2009 - 2010
  • Basic Research for Developmet of New Drugs
    2009 - 2010
  • 成人T細胞性白血病・リンパ腫治療のための創薬研究
    2007 -
  • チトクロームcを介さないカスパーゼ9活性化物質のクローニング
    2003 - 2004
  • チトクロームcを介さないカスパーゼ9活性化物質のクローニング
    2002 - 2003
Education (4):
  • - 1989 Osaka University
  • - 1989 Osaka University Graduate School, Division of Medicine
  • - 1983 Nagasaki University School of Medicine School of Medical Sciences
  • - 1983 Nagasaki University Faculty of Medicine
Professional career (1):
  • (BLANK) (Osaka University)
Work history (13):
  • 2015 - 現在 Nagasaki University School of Medicine Medical University Research Administrator Associate Professor
  • 2007 - 2015 Nagasaki University Graduate School of Biomedical Sciences
  • 2004 - 2007 Nagasaki University Graduate School of Biomedical Sciences
  • 2004 - 2007 Lecturer,Graduate School of Biomedical Science,Graduate School of Biomedical Sciences,Nagasaki University
  • 2007 - Associate Professor,Infection Research,Infection Research,Graduate School of Biomedical Sciences,Nagasaki University
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Association Membership(s) (3):
THE JAPANESE CANCER ASSOCIATION ,  日本分子生物学会 ,  日本生化学会
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