Rchr
J-GLOBAL ID：200901084744979029
Update date: Jan. 31, 2024
Suzuki Fumiaki
スズキ フミアキ | Suzuki Fumiaki
Affiliation and department：
Homepage URL (1)：
http://www.gifu-u.ac.jp/~aob3073/animal_Biochem1.html
Research field (6)：
Applied molecular and cellular biology
, Applied biochemistry
, Molecular biology
, Applied biochemistry
, Cardiology
, Applied biofunctional and bioprocess engineering
Research keywords (40)：
renin-angiotensin system
, receptor
, angiotensin
, renin
, prorenin
, Structural Biology
, Molecular Biology
, Applied Molecular Cell Biology
, Biocehmistry
, 構造生物学
, 分子生物学
, 応用分子細胞生物学
, 動物生化学
, 不活性型レニン
, タンパク質
, 腎
, 不活性型レニン分秘促進因子
, 生物・生体工学
, バイオテクノロジー
, プロレニン分泌促進因子
, プロレニン受容体
, レニン前駆体
, 機能評価
, 血管新生
, 分泌調節
, 分泌促進
, 初期胚
, 分泌
, 腎臓
, 放出促進
, 放出
, 分泌促進物質
, ニワトリ
, プロレニン分泌
, 食の安全
, RT-PCR
, スライス
, レニン・アンジオテンシン
, ラット
, 顎下腺
Research theme for competitive and other funds (22)：
- 2008 - 2013 レニン阻害作用の生化学および臨床研究
- 2007 - 2009 Nanobiomaterial invention using silkworm
- 2006 - 2008 (プロ)レニン受容体の構造と機能についての研究
- 2006 - 2007 プロレニン活性化阻害ペプチドの最適化研究
- 2007 - 岐阜大学奨学寄付金
- 2006 - 岐阜大学奨学寄附金
- 2004 - 2006 鶏初期胚の無殻培養系を用いた食の安全性・機能性の新評価システムの開発
- 2006 - 岐阜大学奨学寄附金
- 2003 - 2005 心血管病に対する創薬を目指した、プロレニンの構造と機能についての研究
- 2004 - 2005 Development of a new evaluation system for safety and function of foods using early stages of chick embryogenesis.
- 1990 - 1991 Purification and characterization of prorenin-relesing-stimulator
- 1988 - 1990 The Study of two new Hormones Regulating Plasma Inactive Renin Release
- Activation mechanism of proteinase precursor
- Basic and applied study on renin-angiotensin system
- Development of overepression syotem for recombinant proteins.
- Molecular Biology of prorenin structure and its function.
- Investigation for catalytic mechanism of renin.
- プロテアーゼ前駆体の活性化機構についての研究
- レニン・アンジオテンシン系の基礎及び応用研究
- 組換えタンパク質の高発現生産系の開発
- プロレニンの構造と機能に関する分子生物学
- 酸素、レニンの反応機構の解明
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Papers (113)：
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Akio Ebihara, Daiki Sugihara, Makoto Matsuyama, Chiharu Suzuki-Nakagawa, A. H. M. Nurun Nabi, Tsutomu Nakagawa, Akira Nishiyama, Fumiaki Suzuki. Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis. Hypertension Research. 2022
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Nariyasu Tahara, Itaru Tachibana, Kazuyo Takeo, Shinji Yamashita, Atsuhiro Shimada, Misuzu Hashimoto, Satoshi Ohno, Takashi Yokogawa, Tsutomu Nakagawa, Fumiaki Suzuki, et al. Boosting Auto-induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives. Protein and peptide letters. 2021. 28. 10. 1180-1190
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Jobaida Akther, Ashish Das, Md Arifur Rahman, Sajoy Kanti Saha, Md Ismail Hosen, Akio Ebihara, Tsutomu Nakagawa, Fumiaki Suzuki, A H M Nurun Nabi. Non-coding Single Nucleotide Variants of Renin and the (Pro)renin Receptor are Associated with Polygenic Diseases in a Bangladeshi Population. Biochemical genetics. 2021
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Asadur Rahman, Makoto Matsuyama, Akio Ebihara, Yuki Shibayama, Arif Ul Hasan, Hironori Nakagami, Fumiaki Suzuki, Jiao Sun, Tomoe Kobayashi, Hiroki Hayashi, et al. Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma. Molecular Cancer Therapeutics. 2020. 19. 9. molcanther.0228.2019-molcanther.0228.2019
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Jobaida Akther, A. H. M, Nurun Nabi, Satoshi Ohno, Takashi Yokogawa, Tsutomu Nakagawa, Fumiaki Suzuki, Akio Ebihara. Establishing a novel assay system for measuring renin concentration using cost effective recombinant ovine angiotensinogen. Heliyon. 2019. 5. 4. e01409
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MISC (152)：
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Shinji Yamashita, Naoya Shibata, Akiyoshi Boku-Ikeda, Erika Abe, Ayumi Inayama, Takashi Yamaguchi, Ayano Higuma, Kaoru Inagaki, Tomoyo Tsuyuzaki, Satoshi Iwamoto, et al. Escherichia coli-based production of recombinant ovine angiotensinogen and its characterization as a renin substrate. BMC BIOTECHNOLOGY. 2016. 16
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Jessica Thomason, Michelle Reyes, Steven R. Allen, Richard O. Jones, Madhava R. Beeram, Thomas J. Kuehl, Fumiaki Suzuki, Mohammad Nasir Uddin. Elevation of (Pro)Renin and (Pro)Renin Receptor in Preeclampsia. AMERICAN JOURNAL OF HYPERTENSION. 2015. 28. 10. 1277-1284
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Yuka Hayakawa, Takuma Aoyama, Chiharu Yokoyama, Chihiro Okamoto, Hisaaki Komaki, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Itta Kawamura, Masanori Kawasaki, et al. High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension. PLOS ONE. 2015. 10. 3
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Chiharu Suzuki-Nakagawa, Misa Nishimura, Masako Noda, Hideyuki Iwata, Masaru Hattori, Akio Ebihara, Fumiaki Suzuki, Tsutomu Nakagawa. Intracellular retention of the extracellular domain of the (pro)renin receptor in mammalian cells. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. 2014. 78. 7. 1187-1190
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Chiharu Suzuki-Nakagawa, Misa Nishimura, Tomoko Tsukamoto, Sho Aoyama, Akio Ebihara, Fumiaki Suzuki, Tsutomu Nakagawa. Participation of the extracellular domain in (pro)renin receptor dimerization. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014. 444. 4. 461-466
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Patents (9)：
Books (6)：
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Renin, Handbook of Proteolytic Enzymes(共著)
Academic Press 1998
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「レニン:遺伝子,構造と機能」、レニン・アンジオテンシン系と高血圧(共著)
先端医学社 1998
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「生理活性ペプチド・レニン」、構造生物学(共著)
朝倉書店 1998
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「レニン・アンジオテンシン系の分子生物学」、高血圧(循環器now5)(共著)
南江堂 1994
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「レニン」、蛋白質分解酵素(]G0001[)(生物化学実験法30)(共著)
学会出版センター 1993
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Lectures and oral presentations (6)：
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Inhibition of nonproteolytic activation of prorenin by a decoy peptide
(2006)
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(PRO)RENIN RECEPTOR: BIOCHEMICAL STUDY ON THE BINDING TO PRORENIN AND RENIN
(2006)
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Role of handle region of prosegment part of prorenin in receptor-assiciated prorenin system.
(2005)
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Role of"handle"region of prosegment part of prorenin in
(2005)
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Role of His(9, P2) and His(13, P3') in angiotensinogen for renin catalytic reaction.
(2004)
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Works (6)：
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Molecular Biology on rat prorenin
2000 -
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ラットプロレニンの分子生物学
2000 -
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Structural Biology on human prorenin
1999 -
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ヒトプロレニンの構造生物学
1999 -
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Structural Biology on sheep angiotensinogen
1998 -
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Education (6)：
Professional career (2)：
- (BLANK) (University of Tsukuba)
- (BLANK) (Kyoto University)
Work history (20)：
- 2020/04 - 現在 Gifu University Fellow
- 2014/04 - 2020/03 Gifu University Executive Director & Vice President
- 2011/04 - 2014/03 Gifu University The United Graduate School of Agricultural Science Dean
- 2004/04/01 - 岐阜大学 教授 応用生物科学部 応用生物化学科
- 2000/04/01 - 2004/03/31 岐阜大学 教授 農学部 生物資源生産学科
- 1995/05/01 - 2000/03/31 岐阜大学 助教授 遺伝子実験施設
- 1999 - 2000 University Tsukuba, Guest Researcher
- 1999 - 2000 University of Tsukuba
- 1988 - 2000 Gifu University, Associate Professor
- 1988 - 2000 Gifu University
- 1989/04/01 - 1995/04/30 岐阜大学 助教授 農学部 生物資源利用学科
- 1994 - 1995 University Tsukuba, Part-time Lecturer
- 1994 - 1995 University of Tsukuba
- 1988/10/01 - 1989/03/31 Gifu University
- 1978 - 1988 Gifu University, Research Assistant
- 1978 - 1988 Gifu University
- 1978/04/01 - 1987/09/30 Gifu University
- 1986 - 1987 University Heidelberg, Alexander von Humboldt Research Fellow
- 1986 - 1987 アレキサンダー・フォン・フルボルトリサーチフェロー(ハイデルベルク大学)
- Gifu University Faculty of Applied Biological Sciences Professor
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Awards (1)：
Association Membership(s) (7)：
ASBMB
, Japanese Biochemical Society
, American Scociety for Biochemistry and Molecular Biology
, 日本蛋白質科学会
, 日本高血圧学会
, 日本生化学会
, 日本農芸化学会
