Research field (4):
Pharmaceuticals - health and biochemistry
, Pharmaceuticals - analytical and physicochemistry
, Chemical biology
, Home economics, lifestyle science
Research theme for competitive and other funds (7):
2013 - 2015 糖尿病克服を目指した有機・無機ナノ複合体である高活性金属錯体の探索研究
2011 - 2013 Development of anti-diabetic zinc medicine protecting the pancreatic B cells through the GPR39-stimulating Pdx-1 expression
2008 - 2010 Development of inorganic zinc-containing medicines with anti-obesity action
2006 - 2007 Development of anti-diabetic agents based on investigating the mechanism of the onset of type 2 diabetes due to protein glycosilation
2005 - 2006 α-グルコシダーゼ阻害効果をもつ金属錯体の開発研究
2004 - 2006 Development of Metal Complexes with Antidialetic Effect
2004 - 2005 Study on development of anti-septic zinc(II) complex with immune-enhancing activity
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Papers (163):
H. Yasui, T. Nishiguchi, Y. Naito, Y. Yoshikawa. Structure and Biological Activity of Zinc Complexes Coordinated with Chalcogen Atoms. Zinc in Biology. 2025. 40-59
Mari Honda, Satomi Minato-Inokawa, Kimie Matsuura, Ayaka Ito, Yuko Nitta, Daisuke Kimura, Yutaka Yoshikawa. The effects of waxy barley on defecation, sleep, mental health, and quality of life: a randomized double-blind parallel-group comparison study. Journal of physiological anthropology. 2025. 44. 1. 12-12
Ryota Saito, Yuki Naito, Yutaka Yoshikawa, Hiroyuki Yasui, Shoko Kikkawa, Huiyeong Ju, Rintaro Ohba, Tae Miyamoto, Shogo Sano, Kazuya Maeda, et al. Synthesis, crystal structure, and insulin-mimetic activity of zinc(ii) complexes with 4-alkyl- and 4,5-dialkyl-3-hydroxythiazole-2(3H)-thiones as a new class of hypoglycemic agent candidates. New Journal of Chemistry. 2025
Yuki Naito, Masaki Kojima, Kana Hayashi, Katsuyuki Tsukamoto, Masayuki Yagi, Yutaka Yoshikawa, Hiroyuki Yasui. Suppressive effects of O4 coordination-type zinc complexes on in vitro AGE formation. Glycative Stress Research. 2024. 11. 1. 33-39
桂莉奈, 池迫里桜, 八木雅之, 近本啓太, 内藤行喜, 安井裕之, 吉川豊. Effects of superfoods on osteoblasts for the purpose of providing functional space diets. 日本薬学会年会要旨集(Web). 2025. 145th
池上慶祐, 内藤行喜, 西藤有希奈, 吉川豊, 安井裕之. Changes in zinc transporter and metallothionein expression in Hepa1-6 cells treated with zinc complexes. 日本薬学会年会要旨集(Web). 2025. 145th
内藤行喜, 宮本麻由, 嶋桃果, 林佳奈, 八木雅之, 義澤克彦, 吉川豊, 安井裕之. The investigation for the effects of cobalt and zinc complexes on suppressing glycation stress and improving diabetic nephropathy. 日本薬学会年会要旨集(Web). 2025. 145th