Rchr
J-GLOBAL ID:200901085254785796   Update date: Apr. 14, 2024

Mihara Hisaaki

ミハラ ヒサアキ | Mihara Hisaaki
Affiliation and department:
Job title: Professor
Other affiliations (1):
Homepage URL  (1): https://mihalab2018.wixsite.com/mihalab
Research field  (7): Bioorganic chemistry ,  Applied biochemistry ,  Applied microbiology ,  Functional biochemistry ,  Structural biochemistry ,  Applied biofunctional and bioprocess engineering ,  Biochemistry
Research keywords  (1): enzyme, trace element, selenium, sulfur, selenoprotein, metal, microbe, chiral compound, bacteria, protein, cofactor, coenzyme, vitamin
Research theme for competitive and other funds  (30):
  • 2024 - 2027 細菌における元素状硫黄呼吸の分子メカニズム
  • 2022 - 2024 セレンタンパク質の革新的生産プラットフォームの開発
  • 2022 - 2024 微生物が駆動し、ヒトと環境を繋ぐセレノダイナミクス
  • 2020 - 2023 Dynamics of selenium metabolisms and diversity of their molecular mechanisms in microbes
  • 2018 - 2020 Development and application of expression system for active selenoproteins
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Papers (116):
  • Atsuki Shimizu, Ryuta Tobe, Riku Aono, Masao Inoue, Satoru Hagita, Kaito Kiriyama, Yosuke Toyotake, Takuya Ogawa, Tatsuo Kurihara, Kei Goto, et al. Initial step of selenite reduction via thioredoxin for bacterial selenoprotein biosynthesis. International Journal of Molecular Sciences. 2021. 22. 20
  • Masao Inoue, Yuu Hirose, Ryuta Tobe, Shigeki Saito, Riku Aono, N Tejo Prakash, Hisaaki Mihara. Complete Genome Sequence of Pseudomonas stutzeri Strain F2a, Isolated from Seleniferous Soil. Microbiology resource announcements. 2021. 10. 33. e0063121
  • Yuu Hirose, Jakkaphan Kumsab, Ryuta Tobe, Hisaaki Mihara. Complete Genome Sequence of an Acetic Acid Bacterium, Acetobacter aceti JCM20276. Microbiology resource announcements. 2020. 9. 42
  • Jakkaphan Kumsab, Ryuta Tobe, Tatsuo Kurihara, Yuu Hirose, Taketo Omori, Hisaaki Mihara. Characterization of a novel class of glyoxylate reductase belonging to the β-hydroxyacid dehydrogenase family in Acetobacter aceti. Bioscience, biotechnology, and biochemistry. 2020. 84. 11. 1-8
  • 戸部隆太, 三原久明. 必須微量元素セレンの生理作用と代謝 ~セレンタンパク質の機能とセレン代謝~. 化学と生物. 2019. 57. 6. 366-372
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MISC (7):
  • 青野陸, 井上真男, 三原久明. 必須微量元素セレンの微生物による多彩な代謝. ファルマシア. 2023. 59. 3. 185-189
  • 葛野侑香, 生田帆河, 西田亮, 戸部隆太, 広瀬侑, PRAKASH Tejo, 三原久明. Bacillus sp.NTP-1株における新規テルル酸還元酵素の同定とその機能解析. 日本農芸化学会大会講演要旨集(Web). 2018. 2018. ROMBUNNO.2A25p14 (WEB ONLY)
  • 桐山海斗, 清水敦貴, 片山碧, 戸部隆太, 広瀬侑, PRAKASH N. Tejo, 三原久明. セレン耐性菌Pseudomonas sp.F2a株のチオレドキシンシステムの解析. 日本微量栄養素学会学術集会講演要旨集. 2017. 34th. 7
  • Suguru Kurokawa, Masanori Takehashi, Hiromitsu Tanaka, Hisaaki Mihara, Tatsuo Kurihara, Seigo Tanaka, Kristina Hill, Raymond Burk, Nobuyoshi Esaki. Mammalian Selenocysteine Lyase Is Involved in Selenoprotein Biosynthesis (vol 57, pg 298, 2011). JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 2015. 61. 6. 543-543
  • Possible role of red blood cells in selenocysteine metabolism. Trace nutrients research. 2009. 26. 22-25
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Books (12):
  • エッセンシャル タンパク質工学
    講談社 2018
  • Selenium in Plants
    Springer 2017
  • Selenium: Its Molecular Biology and Role in Human and Health 4th Ed.
    Springer 2016
  • 地球を救うメタルバイオテクノロジー -微生物と金属資源のはなし-
    成山堂書店 2014 ISBN:9784425800018
  • Selenium in the Environment and Human Health
    CRC Press, London 2014
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Lectures and oral presentations  (215):
  • Bacillus属細菌におけるテルル酸還元酵素の解析
    (メタルバイオサイエンス研究会2018 2018)
  • Cellulomonas sp. D3a 株の亜セレン酸還元機構の解析
    (第6回メタロミクス研究フォーラム 2018)
  • Pseudomonas putidaのD-リジン異化代謝オペロン転写制御因子の解析
    (第454回ビタミンB研究協議会 2018)
  • Purification and characterization of a putative rhodanese-like protein GSU2940 from Geobacter sulfurreducens
    (The 7th International Selenium Conference (Se2018) 2018)
  • Functional analysis of a novel porin-like protein, ExtI, from Geobacter sulfurreducens and its implication in selenite and tellurite reduction
    (The 7th International Selenium Conference (Se2018) 2018)
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Education (3):
  • - 1999 Kyoto University "Graduate School, Division of Agriculture" Agricultural Chemistry Major
  • - 1995 Kyoto University "Graduate School, Division of Agriculture" Agricultural Chemistry Major
  • - 1993 Kyoto Prefectural University Faculty of Agriculture Department of Agricultural Chemistry
Professional career (1):
  • Ph.D. (Agriculture) (Kyoto University)
Work history (6):
  • 2014/04 - Professor, College of Life Sciences, Ritsumeikan University
  • 2009/04 - 2014/03 Associate Professor, College of Life Sciences, Ritsumeikan University
  • 2007/04 - 2009/03 Kyoto University Institute for Chemical Research
  • 2000/04 - 2007/03 Kyoto University Institute for Chemical Research
  • 1999/04 - 2000/03 Kyoto University Institute for Chemical Research
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Committee career (15):
  • 2015/11 - 2021/10 日本ビタミン学会 代議員
  • 2019/01 - 2020/12 日本生化学会 「生化学」誌企画委員
  • 2018/04 - 2020/03 ビタミンB研究委員会 準委員
  • 2015/11 - 2019/11 日本生化学会 代議員
  • 2017/10 - 2019/09 日本生化学会近畿支部 庶務幹事
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Awards (1):
  • 2010 - 日本生化学会奨励賞
Association Membership(s) (6):
日本生物高分子学会 ,  Japan Trace Nutrients Research Society ,  Japan Society for Biomedica1 Research on Trace Elements ,  THE VITAMIN SOCIETY OF JAPAN ,  "Japan Society for Bioscience, Biotechnology, and Agrochemistry " ,  The Japanese Biochemical Society
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