Rchr
J-GLOBAL ID:200901086343893787   Update date: Feb. 07, 2021

Makoto Arita

Makoto Arita
Research field  (4): Medical biochemistry ,  Pharmaceuticals - health and biochemistry ,  Functional biochemistry ,  Molecular biology
Research keywords  (5): Lipid Biochemistry ,  Bioactive molecules ,  Regulation of Inflammation ,  Lipoquality ,  Metabolomics
Research theme for competitive and other funds  (11):
  • 2020 - 2024 脂肪酸代謝ネットワークによる生体制御およびその制御破綻による疾患メカニズムの解明
  • 2015 - 2020 「リポクオリティ」領域研究の国際連携
  • 2015 - 2020 「リポクオリティ」領域研究の推進
  • 2015 - 2020 脂肪酸クオリティの最先端リピドミクスと生理的意義の解明
  • 2015 - 2018 脂質代謝バランス異常を伴う疾患の病態解明と創薬に向けた基盤研究
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Papers (128):
  • Hirata T, Yamamoto K, Ikeda K, Arita M. Functional lipidomics of vascular endothelial cells in response to laminar shear stress. FASEB Journal. 2021. 35. e21301
  • Johmura Y, Yamanaka T, Omori S, Wang T, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, et al. Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders. Science. 2021. 371. 265-270
  • Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, et al. Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. J Exp Med. 2021. 218. e20200815
  • Yasuda S, Okahashi N, Tsugawa H, Ogata Y, Ikeda K, Suda W, Arai H, Hattori M, Arita M. Elucidation of gut microbiota-associated lipids using LC-MS/MS and 16S rRNA sequence analyses. iScience. 2020. 23. 101841
  • Kokaji T, Hatano A, Ito Y, Yugi K, Eto M, Morita K, Ohno S, Fujii M, Hironaka K, Egami R, et al. Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity. Sci Signal. 2020. 13. eaaz1236
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MISC (18):
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Patents (6):
  • 新規抗炎症性化合物
  • アレルギー性疾患の予防または治療のための医薬組成物
  • Therapeutic Agent against Influenza
  • 光学活性な新規抗炎症性代謝物
  • オメガ3脂肪酸由来の新規抗炎症性代謝物
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Books (8):
  • 医学のあゆみ増刊:脂質クオリティ研究の基礎と臨床(有田誠/編)
    医歯薬出版 2019
  • 実験医学増刊:脂質クオリティ -生命機能と健康を支える脂質の多様性-(有田誠/編)
    羊土社 2018
  • ヒトマイクロバイオーム研究最前線
    NTS 2016
  • Chronic Inflammation, Mechanisms and Regulation (Miyasaka M, Takatsu K, eds.)
    Springer 2016
  • Bioactive Lipid Mediator (Yokomizo T, Murakami M, eds.)
    Springer 2015
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Lectures and oral presentations  (221):
  • Biology of LipoQuality: Advanced lipidomics technology and its application in biology
    (MBSJ2020 2020)
  • 最先端リピドミクスから解き明かす病態・バイオロジー研究
    (第45回日本医用マススペクトル学会年会 2020)
  • 脂質代謝ネットワークによる炎症性疾患の制御
    (第93回日本生化学会大会 2020)
  • Biology of LipoQuality: Omega-3 fatty acid cascade that controls inflammation and tissue homeostasis
    (第93回日本薬理学会年会 2020)
  • Advanced lipidomics to unveil the potential link between lipid metabolism and biological phenotypes
    (RIKEN Glyco-lipidologue Project Symposium 2020 2020)
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Education (3):
  • 1994 - 1997 The University of Tokyo
  • 1992 - 1994 The University of Tokyo
  • 1988 - 1992 The University of Tokyo
Work history (10):
  • 2016/06/01 - 現在 Keio University Faculty of Pharmacy Professor
  • 2014/04/01 - 現在 RIKEN Center for Integrative Medical Sciences Team Leader
  • 2014/04/01 - 現在 Yokohama City University Graduate School of Medical Life Science Visiting Professor
  • 2014/04/01 - 現在 RIKEN Center for Integrative Medical Sciences Team Leader
  • 2007/04/01 - 2014/03/31 The University of Tokyo Graduate School of Pharmaceutical Sciences Associate Professor
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Awards (3):
  • 2016 - 日本脂質栄養学会ランズ賞学術賞
  • 2009 - Young Scientists' Prize of Ministry of Education, Culture, Sports, Science and Technology, Japan
  • 2005 - Young Investigator Award: 9th International Conference of Eicosanoids other Bioactive Lipids in Cancer, Inflammation & Related Diseases (San Francisco)
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