Research field (4)：
Molecular biology
, Functional biochemistry
, Biological pharmacy
, General medical chemistry
Research keywords (5)：
Metabolomics
, Lipoquality
, Regulation of Inflammation
, Bioactive molecules
, Lipid Biochemistry
Research theme for competitive and other funds (10)：
2015 - 2020 「リポクオリティ」領域研究の国際連携
2015 - 2020 脂肪酸クオリティの最先端リピドミクスと生理的意義の解明
2015 - 2020 「リポクオリティ」領域研究の推進
2015 - 2018 脂質代謝バランス異常を伴う疾患の病態解明と創薬に向けた基盤研究
2010 - 2015 ω3系脂肪酸の代謝と生理的機能についての包括的メタボローム解析
2010 - 2015 「脂質マシナリー」領域研究の推進
2010 - 2014 炎症の収束機構の分子基盤の確立と慢性疾患への適用
2009 - 2011 ω3脂肪酸由来の新規抗炎症性メディエーターの同定および作用機構の解析
2006 - 2010 炎症反応の収束に関わる脂質性メディエーターの代謝と網羅的解析
1998 - 1999 α-トコフェロール輸送蛋白質による体内ビタミンEレベルの決定機構の解析
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Papers (118)：
Shishikura K, Kuroha S, Matsueda S, Iseki H, Matsui T, Inoue A, *Arita M. Acyl-CoA synthetase 6 regulates long chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice. FASEB J. 2019. 33. 12. 14194-14203
Nakashima Y, *Sakai Y, Mizuno Y, Furuno K, Hirono K, Takatsuki S, Suzuki H, Onouchi Y, Kobayashi T, Tanabe K, Hamase K, Miyamoto T, Aoyagi R, Arita M, Yamamura K, Tanaka T, Nishio H, Takada H, Ohga S, *Hara T. Lipidomics links oxidized phosphatidylcholines and coronary arteritis in Kawasaki disease. Cardiovasc Res. 2019
Sawane K, Nagatake T, Hosomi K, Hirata S, Adachi J, Abe Y, Isoyama J, Suzuki H, Matsunaga A, Fukumitsu S, Aida K, Tomonaga T, Arita M, *Kunisawa J. Dietary omega-3 fatty acid ameliorates allergic rhinitis via eosinophilic production of the anti-allergic lipid mediator 15-hydroxyeicosapentaenoic acid in mice. Nutrients. 2019. 11. 2868
Watanabe Y, *Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, *Takatsu K. Bi-directional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation. FASEB J. 2019. 33. 11. 11821-11835
Naoe S, *Tsugawa H, Takahashi M, Ikeda K, *Arita M. Characterization of lipid profiles after dietary intake of polyunsaturated fatty acids using integrated untargeted and targeted lipidomics. Metabolites. 2019. 9. 241
Yamamoto T, *Miyata J, Arita M, Fukunaga K, Kawana A. Current state and future prospect of therapeutic strategy targeting cysteinyl leukotriene metabolism in asthma. Respir Invest. 2019. 57. 6. 534-543
Ishihara T, Yoshida M, *Arita M. Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis. Int Immunol. 2019. 31. 9. 559-567
Miyata J, *Fukunaga K, Kawashima Y, Ohara O, Arita M. Cysteinyl leukotriene metabolism of human eosinophils in allergic disease. Allergol Int. 2019
Tsugawa H, Ikeda K, Arita M. The importance of bioinformatics for connecting data-driven lipidomics and biological insights. Biochim Biophys Acta. 2017. 1862. 762-765
*Arita M. Eosinophil polyunsaturated fatty acid metabolism and its potential control of inflammation and allergy. Allergol Int. 2016. 65. S2-S5
Novel omega-3 autacoid resolving E1: receptor identification and anti-inflammatory properties
(36th Annual Meeting of the Society for Leukocyte Biology 2003)
ω3 derived lipid mediator resolvin E1: stereochemistry, receptor and anti-inflammatory and protective action in colitis
(9th International Conference of Bioactive Lipids in Cancer, Inflammation and Related Diseases 2005)
Novel protective lipid mediators and neutrophils: resolvins and protectins
(International Symposium of Molecular Cell Biology of Macrophages and Dendritic cells 2006 2006)
1988 - 1992 The University of Tokyo Faculty of Pharmaceutical Sciences
1992 - 1994 The University of Tokyo Graduate School of Pharmaceutical Sciences
1994 - 1997 The University of Tokyo Graduate School of Pharmaceutical Sciences
Work history (8)：
1997/04/01 - 2000/06/30 The University of Tokyo Assistant Professor
2000/07/01 - 2003/06/30 Harvard Medical School Postdoctoral Fellow
2003/07/01 - 2006/09/30 Harvard Medical School Instructor
2006/10/01 - 2007/03/31 JST Researcher
2007/04/01 - 2014/03/31 The University of Tokyo Associate Professor
2014/04/01 - 現在 RIKEN Team Leader
2014/04/01 - 現在 Yokohama City University Visiting Professor
2016/06/01 - 現在 Keio University Professor
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Awards (3)：
2005 - Young Investigator Award: 9th International Conference of Eicosanoids other Bioactive Lipids in Cancer, Inflammation & Related Diseases (San Francisco)
2009 - Young Scientists' Prize of Ministry of Education, Culture, Sports, Science and Technology, Japan
