Rchr
J-GLOBAL ID：200901086680476462   Update date: Feb. 01, 2024

Itoh Kazuyuki

イトウ カズユキ | Itoh Kazuyuki
Affiliation and department：
Osaka Prefectural Hospital Organization, Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases Biology

About Osaka Prefectural Hospital Organization, Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases Biology


Job title： Head
Other affiliations (1)：
Research field  (3)： Tumor biology ,  Orthopedics ,  Experimental pathology
Research keywords  (9)： がんの転移・浸潤 ,  細胞運動 ,  Rhoキナーゼ ,  Rho ,  osteo genesis ,  cell motility ,  Rho kinase ,  Rho ,  myosin
Research theme for competitive and other funds  (20)：
  • 2015 - 2018 Understanding molecular mechanism underlying innate immune system escape for metastasis in sarcoma
  • 2015 - 2018 Development of novel target therapy for metastatic organ of malignant soft tissue tumor
  • 2013 - 2015 Development of the novel ant-metastatuc therapy against circulating tumor cells
  • 2012 - 2015 Investigation of collective molecular mechanisms in stemness and metastasis in sarcoma
  • 2011 - 2014 Development of novel target therapy for soft tissue sarcoma stem cells
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Papers (98)：
  • Daluthgamage Patsy Himali Wijesekera, Eiji Yuba, Nadeeka Harshini De Silva, Shun-Ichi Watanabe, Masaya Tsukamoto, Chihiro Ichida, Takeshi Izawa, Kazuyuki Itoh, Ryoji Kanegi, Shingo Hatoya, et al. Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy. FASEB bioAdvances. 2020. 2. 1. 5-17
  • Nishimura, Y, Itoh, K. Involvement of SNX1 in regulating EGFR endocytosis in a gefitinib-resistant NSCLC cell lines (Review). Cancer Drug Resistance. 2019. DOI: 10.20517/cdr.2019.15
  • Hidemitsu Nakagawa, Yoshihiro Yui, Satoru Sasagawa, Kazuyuki Itoh. Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis. Journal of neuro-oncology. 2018. 139. 1. 43-50
  • Nakagawa, H., Sasagawa, S., Itoh, K. Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells. Oncology Letters. 2018. 15. 2. 1495-1502
  • Takaaki Nakai, Yoshinori Imura, Hironari Tamiya, Shutaro Yamada, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, et al. Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma. Cancer medicine. 2017. 6. 9. 2121-2130
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MISC (89)：
  • Sho Nakai, Takaaki Nakai, Naohiro Yasuda, Shutaro Yamada, Satoshi Takenaka, Yoshinori Imura, Hironari Tamiya, Takaaki Tanaka, Nobuhito Araki, Kazuyuki Itoh, et al. Anti-tumor effects of Eribulin mesilate on clear cell sarcoma cell lines. CANCER SCIENCE. 2018. 109. 380-380
  • Takaaki Nakai, Yoshinori Imura, Sho Nakai, Naohiro Yasuda, Shutaro Yamada, Satoshi Takenaka, Hironari Tamiya, Takaaki Tanaka, Nobuhito Araki, Kazuyuki Itoh, et al. Anti-tumor effects of a selective MET inhibitor on clear cell sarcoma cell lines. CANCER SCIENCE. 2018. 109. 569-569
  • Shutaro Yamada, Hidetatsu Outani, Naohiro Yasuda, Takaaki Nakai, Sho Nakai, Yoshinori Imura, Takaaki Tanaka, Hironari Tamiya, Satoshi Takenaka, Kenichiro Hamada, et al. Establishment of a small round cell sarcoma cell line (Kitra-SRS) harboring a novel variant of CIC-DUX4 fusion gene. CANCER SCIENCE. 2018. 109. 645-645
  • 中井 翔, 中井 隆彰, 安田 直弘, 山田 修太郎, 竹中 聡, 伊村 慶紀, 田宮 大也, 田中 太晶, 荒木 信人, 伊藤 和幸, et al. 淡明細胞肉腫に対するEribulin mesilateの抗腫瘍効果. 日本癌学会総会記事. 2017. 76回. P-1421
  • 中井 隆彰, 伊村 慶紀, 中井 翔, 安田 直弘, 山田 修太郎, 竹中 聡, 田宮 大也, 田中 太晶, 荒木 信人, 伊藤 和幸, et al. 淡明細胞肉腫に対する選択的MET阻害剤の抗腫瘍効果. 日本癌学会総会記事. 2017. 76回. J-2101
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Patents (2)：
  • Rhoキナーゼ阻害活性を有する化合物と骨誘導因子を含む事を特徴とする骨形成促進剤 1999-9-2 出願中
  • Rhoキナーゼ阻害活性を有する化合物を含有してなる骨形成促進剤 1999-6-18 出願中
Education (2)：
  • 1983 - 1987 大阪大学大学院医学部
  • 1977 - 1983 Yamaguchi University School of Medicine
Professional career (1)：
  • Medical Doctor (MD), Physical Doctor (PhD)
Work history (4)：
  • 2018/04 - 奈良県立医科大学 非常勤講師
  • 1992/07 - - National Institute of Health, NHLBI, Lab of Mol.
  • 1989/02 - - 大阪府立成人病センター研究所
  • 1987/04 - - 大阪大学医学部第4内科 医員
Committee career (1)：
  • 日本学術振興会 科学研究補助金 専門委員
Awards (22)：
  • 持田記念医学薬学振興財団研究助成
  • 平成12年度武田科学振興財団研究奨励金
  • 平成11年度高松宮妃癌研究基金研究助成金
  • 平成11年度ベルツ賞(2等共同受賞)
  • 平成11年度東京生化学研究会研究奨励金
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Association Membership(s) (7)：
JAMR ,  米国細胞生物学会 ,  日本生化学会 ,  日本癌学会 ,  The Japanese Biochemical Society ,  The American Society for Cell Biology ,  Japanese Cancer Association
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