Rchr
J-GLOBAL ID:200901086826567392   Update date: May. 08, 2025

Takizawa Toshihiro

Takizawa Toshihiro
Research field  (3): Obstetrics and gynecology ,  Anatomy ,  Digestive surgery
Research theme for competitive and other funds  (39):
  • 2024 - 2027 胎盤由来細胞間輸送体の新パラダイムによる妊娠高血圧腎症・早産の病態解明と発症予知
  • 2022 - 2025 A novel prediction of placenta accreta spectrum using circulating microRNA in in the first trimester
  • 2022 - 2025 A study on clinical implementation of response guided therapy with neoadjuvant endocrine therapy for breast cancer.
  • 2020 - 2024 Elucidation of the novel function of trophoblast DROSHA as a novel therapeutic strategy for preventing congenital viral infection
  • 2018 - 2023 前立腺癌の骨転移における lncRNA の機能解明と新規治療法開発の基盤形成
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Papers (24):
  • Shohei Tozawa, Hironori Takahashi, Syunya Noguchi, Takami Takizawa, Takanobu Sakurai, Akihide Ohkuchi, Hiroyuki Fujiwara, Toshihiro Takizawa. Upregulation of Autophagy During the Differentiation of Primary Human Term Cytotrophoblast Cells into Syncytial Cells: Ultrastructural Analysis. International Journal of Molecular Sciences. 2025. 26. 3. 1321-1321
  • 瀧澤 俊広, 野口 隼矢, 高橋 宏典, 大口 昭英, 藤原 寛行. ヒト絨毛栄養膜細胞のDROSHA 胎盤特異的microRNA産生とウイルス感染防御. Reproductive Immunology and Biology. 2024. 39. 1-2. 1-10
  • Syunya Noguchi, Yasuyuki Negishi, Shohei Tozawa, Takanobu Sakurai, Takami Takizawa, Rimpei Morita, Akihide Ohkuchi, Hironori Takahashi, Hiroyuki Fujiwara, Toshihiro Takizawa. Novel extracellular nanoparticles secreted by human villous trophoblast cells influence peripheral blood mononuclear cells. Placenta. 2024. 154. 235-236
  • Hikaru Mikami, Syunya Noguchi, Jun Akatsuka, Hiroya Hasegawa, Kotaro Obayashi, Hayato Takeda, Yuki Endo, Yuka Toyama, Hiroyuki Takei, Go Kimura, et al. snRNAs from Radical Prostatectomy Specimens Have the Potential to Serve as Prognostic Factors for Clinical Recurrence after Biochemical Recurrence in Patients with High-Risk Prostate Cancer. Cancers. 2024. 16. 9. 1757-1757
  • Syunya Noguchi, Sadayuki Ohkura, Yasuyuki Negishi, Shohei Tozawa, Takami Takizawa, Rimpei Morita, Hironori Takahashi, Akihide Ohkuchi, Toshihiro Takizawa. Cytoplasmic and nuclear DROSHA in human villous trophoblasts. Journal of Reproductive Immunology. 2024. 162. 104189-104189
more...
MISC (90):
  • Syunya Noguchi, Junxiao Wang, Shan-Shun Luo, Toshihiro Takizawa. Placenta-specific lncRNA 1600012P17Rik modulates the expression of the neighboring protein-coding gene Pappa2. Placenta. 2022. 128. 132-132
  • Ai Sato, Syunya Noguchi, Hiroyuki Takei, Toshihiro Takizawa. PLACENTA-SPECIFIC MICRORNAS SUPPRESS HMGB3 IN BREAST CANCER CELL LINE MCF-7. PLACENTA. 2022. 128. 132-132
  • Shohei Tozawa, Syunya Noguchi, Takanobu Sakurai, Akihide Ohkuchi, Hironori Takahashi, Hiroyuki Fujiwara, Toshihiro Takizawa. STRUCTURAL CHARACTERISTICS OF EXOSOMES AND NANOPARTICLES DERIVED FROM TROPHOBLAST CELL LINE BEWO. PLACENTA. 2022. 128. 131-132
  • Syunya Noguchi, Takanobu Sakurai, Yukihiro Kondo, Toshihiro Takizawa. Identification and characterization of nanoparticles secreted from the prostate cancer cell line PC-3. Journal of Reproductive Immunology. 2022. 153. 103725-103725
  • Syunya Noguchi, Toshihiro Takizawa. Expression analysis of the alternative splicing of DROSHA in the trophoblast cell line BeWo. Placenta. 2021. 114. 143-143
more...
Lectures and oral presentations  (7):
  • Delivery of prostate cancer-associated non-coding RNAs within the bone marrow milieu
    (Journal of Reproductive Immunology 2023)
  • Trophoblast cell line BeWo cell-derived nanoparticles contain a large amount of placenta-specific microRNAs and modify the gene expression of recipient immune cells (T lymphocyte cell line Jurkat cells)
    (Journal of Reproductive Immunology 2023)
  • Placenta-specific lncRNA 1600012P17Rik modulates the expression of the neighboring protein-coding gene Pappa2
    (Placenta 2022)
  • Nanoparticles secreted from trophoblast cell line BeWo
    (Journal of Reproductive Immunology 2022)
  • Identification and characterization of nanoparticles secreted from the prostate cancer cell line PC-3
    (Journal of Reproductive Immunology 2022)
more...
Education (4):
  • - 1994 Jichi Medical University
  • - 1994 Jichi Medical University Graduate School, Division of Medicine
  • - 1986 Jichi Medical University
  • - 1986 Jichi Medical University Faculty of Medicine
Work history (1):
  • Nippon Medical School Molecular Anatomy and Medicine Professor
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