Rchr
J-GLOBAL ID:200901086826684887   Update date: Nov. 15, 2019

AIBA Hirofumi

アイバ ヒロフミ | AIBA Hirofumi
Affiliation and department:
Job title: Professor
Research keywords  (4): Lifespan ,  Aging ,  Signal transduction ,  Transcriptional regulation
Papers (90):
  • Ohtsuka, H*. Kato, T*, Sato, T., Shimasaki, T., Kojima, T., and Aiba, H. Leucine depletion extends the lifespans of leucine-auxotrophic fission yeast by inducing Ecl1 family genes via the transcription factor Fil1. Mol. Genet. Genomics. 2019. 2019 in press
  • Imai, Y.*, Shimasaki, T.*, Enokimura, C., Ohtsuka, H., Tsubouchi, S., Ihara, K., and Aiba, H. gas1 mutation extends chronological lifespan via Pmk1 and Sty1 MAPKs in Schizosaccharomyces pombe. Biosci. Biotech. Biochem. 2019. in press
  • Hibi, T.*, Ohtsuka, H.*, Shimasaki, T., Inui, S., Shibuya, M., Tatsukawa, H., Kanie, K., Yamamoto, Y., and Aiba, H. Tschimganine and its derivatives extend the chronological life span of yeast via activation of the Sty1 pathway. Genes to Cells. 2018. 23. 620-637
  • Ohtsuka, H.*, Takinami, M.*, Shimasaki, T., Hibi, T., Murakami, H., and Aiba, H. Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome. Molecular Microbiology. 2017. 105. 84-97
  • Shimasaki, T., Ohtsuka, H., Naito, C., Azuma, K., Tenno, T., Hiroaki, H., Murakami, H., and Aiba, H. Ecl1 is a zinc-binding protein involved in the zinc-limitation-dependent extension of chronological lifespan in fission yeast. Mol. Genet. Genomics. 2017. 292. 2. 475-481
more...
MISC (88):
  • Hibi, T.*, Ohtsuka, H.*, Shimasaki, T., Inui, S., Shibuya, M., Tatsukawa, H., Kanie, K., Yamamoto, Y., and Aiba, H. Tschimganine and its derivatives extend the chronological life span of yeast via activation of the Sty1 pathway. Genes to Cells. 2018. 23. 620-637
  • Ohtsuka, H.*, Takinami, M.*, Shimasaki, T., Hibi, T., Murakami, H., and Aiba, H. Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome. Molecular Microbiology. 2017. 105. 84-97
  • Shimasaki, T., Ohtsuka, H., Naito, C., Azuma, K., Tenno, T., Hiroaki, H., Murakami, H., and Aiba, H. Ecl1 is a zinc-binding protein involved in the zinc-limitation-dependent extension of chronological lifespan in fission yeast. Mol. Genet. Genomics. 2017. 292. 2. 475-481
  • Hori, M.*, Oka, S*., Sugie, Y., Ohtsuka, H. and Aiba, H. Construction of a photo-responsive chimeric histidine kinase in Escherichia coli. J. Gen. Appl. Microbiol. 2017. 63. 44-50
  • Kurauchi, T.*, Hashizume, A.*, Imai, Y., Hayashi, K., Tsubouchi, S., Ihara, K., Ohtsuka, H., and Aiba, H. Identification of a novel protein kinase that affects on the chronological lifespan in fission yeast. FEMS Microbiology Letters. 2017. 364. fnw257
more...
Books (1):
  • Genome-Wide Analysis of Escherichia coli Histidine Kinases.
    Histidine Kinases in Signal Transduction. 2003
Lectures and oral presentations  (154):
  • "Mechanism of gene activation by the Escherichia coli positive regulator, OmpR: Study on mutants defective in transcriptional activation"
    (FASEB Summer Research Conferences: Transcription Initiation in Prokaryotes 1995)
  • 光合成細菌ラン藻の外膜タンパク質遺伝子の取得とその解析
    (日本農芸化学会1995年度大会 1995)
  • 大腸菌転写因子OmpRのDNA結合ドメインの解析.
    (日本農芸化学会1995年度大会 1995)
  • ラン藻(Synechococcus PCC7942)よりクローニングされた細胞内情報伝達に関与する遺伝子の解析
    (日本農芸化学会1995年度大会 1995)
  • 分裂酵母における浸透圧応答機構の解析
    (日本農芸化学会1995年度大会 1995)
more...
Education (2):
  • - 1985 Nagoya University Faculty of Agriculture
  • - 1990 Nagoya University Graduate School, Division of Agriculture
Work history (5):
  • 2007/04/01 - 2012/03/31 Nagoya University Associate professor
  • 2016/04/01 - 2017/03/31 Nagoya University
  • 2007/03/31 - Nagoya University Assistant Professor
  • 2012/04/01 - 現在 Nagoya University Professor
  • 2017/04/01 - 現在 Nagoya University
Association Membership(s) (1):
The Phamaceutical Society of Japan
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