Koyasu Shigeo

2006 - 2011 Role of dendritic cells in bridging innate and adaptive immune responses during bacterial infection (2006-2011)

2010 - 2010 Role of natural helper cell in anti-helminth immunity (2010)

2006 - 2008 Mechanism for antigen capture during Helicobacter infection (2006-2008)

2006 - 2008 Role of PI3-kinase in anti-helminth immunity involving IgE and gastrointestinal mast cells (2006-2008)

2002 - 2008 Development of new therapies for infectious diseases through understanding of the symbiosis strategy of pathogenic microbes (2002-2008)

2005 - 2006 Role of gut-associated lymphoid tissues in Helicobacter infection (2005-2006)

2004 - 2006 Role of PI3-kinase in the development and function of mast cells (2004-2006)

2002 - 2006 The regulation of innate immune responses by dendritic cells through the interaction with microbes (2002-2006)

2002 - 2005 Artificial regulation of immune system through the PI3K signaling (2002-2005)

2005 - Role of PI3K/NF-κB pathway in B cell functions (2005-2006)

2002 - 2004 Role of PI3-kinase in the development of mast cells and anti-helminth immunity (2002-2004)

2001 - 2003 Mechanisms of B cell tolerance against peripheral antigen (2001-2003)

2000 - 2003 Development of new animal models for autoimmune neuronal diseases (2000-2003)

2001 - 2002 Role of interaction of dendritic cells and pathogenic microbes in innate immunity (2001-2002)

2000 - 2002 Novel targets of cyclosporin A and FK506 (2000-2002)

1999 - 2002 T cell receptor signal transduction involved in T cell anergy (1999-2002)

1997 - 2002 Functional analysis of cellular immunity in infectious diseases (1997-2002)

2000 - 2001 Regulation of Th1 and Th2 responses by interferon-γ produced by dendritic cells (2000-2001)

1999 - 2001 Cellular mechanisms of tolerance breakdown in autoantibody production (1999-2001)

1996 - 2000 Studies on the rejection of transplanted bone marrow cells by NK and NKT cells (1996-2000)

1998 - 1999 ITAM: a signal transduction motif mediating T cell receptor signals (1998-1999)

1998 - 1999 Function of the T cell-specific MAPK cascade (1998-1999)

1997 - 1999 Regulation of the T cell receptor expression by molecular chaperons (1997-1999)

1997 - 1999 Signal transduction of the T cell receptor in T cell anergy (1997-1999)

1997 - 1998 Function of MAPK superfamily in the T cell receptor-mediated signal transduction (1997-1998)

1996 - 1998 Functional analysis of peripheral tolerance (1996-1998)

1996 - 1997 Differentiation mechanisms of T cells and NK cells (1996-1997)

1996 - 1997 Factors determining the sensitivity of T cell receptor signals (1996-1997)

1993 - 1996 Functional analysis of FcεRIγ in T cell receptors in LGL (1993-1996)

1993 - 1996 Functional analysis of FcεRIγ in T cell receptors on LGL (1993-1996)

1989 - 1991 Human T cell recognition of HIV envelope glycoproteins (1989-1991)

1987 - 1988 Elucidation of switch mechanisms between resting and growth phases using cloned T cells (1987-1988)

1986 - 1987 Role of intracellular calcium ion on the production of IL-2 and expression of the IL-2 receptor (1986-1987)

1985 - 1987 Regulatory mechanisms of cell growth mediated by growth factors and their receptors (1985-1987)

1983 - 1985 Structure and function of immune cell growth factors (1983-1985)