Rchr
J-GLOBAL ID:200901087159856506   Update date: Jul. 14, 2020

Tomiyama Yoshiaki

トミヤマ ヨシアキ | Tomiyama Yoshiaki
Affiliation and department:
Other affiliations (1):
  • Osaka University  Faculty of Medicine, Medical School, Dept of Hematology and Oncology   Associate Professor,Associate Professor
Homepage URL  (1): http://www.med.osaka-u.ac.jp/pub/bldon/www/home.html
Research field  (3): Hematology and oncology ,  Cell biology ,  Molecular biology
Research keywords  (3): ITP ,  GPIIb-IIIa ,  Platelet
Research theme for competitive and other funds  (3):
  • Study on anti-platelet autoantibodies in chronic ITP
  • Molecular genetic basis of Glanzmann's thrombasthenia
  • Structure-function relationship in integrin αIIbβ3
Papers (53):
  • Akuta K, Kiyomizu K, Kashiwagi H, Kunishima S, Nishiura N, Banno F, Kokame K, Hisashi K, Kanakura Y, Miyata T, Tomiyama Y. Knock-in mice bearing constitutively active αIIb(R990W) mutation develop macrothrombocytopenia with severe platelet dysfunction. Journal of thrombosis and haemostasis : JTH. 2019
  • Ueda Tomoaki, Maeda Tetsuo, Fukushima Kentaro, Fujita Jiro, Kusakabe Shinsuke, Yokota Takafumi, Shibayama Hirohiko, Tomiyama Yoshiaki, Kanakura Yuzuru. Addition of Melphalan to Fludarabine/Busulfan (FLU/BU4/MEL) Provides Survival Benefit for Patients with Myeloid Malignancy Following Allogeneic Bone Marrow Transplantation/Peripheral Blood Stem Cell Transplantation. The American Society of Hematology 60th Annual Meeting. 2018. 132
  • Morikawa Y, Kato H, Kashiwagi H, Nishiura N, Akuta K, Honda S, Kanakura Y, Tomiyama Y. Protease-activated receptor-4 (PAR4) variant influences on platelet reactivity induced by PAR4-activating peptide through altered Ca2+ mobilization and ERK phosphorylation in healthy Japanese subjects. Thrombosis research. 2018. 162. 44-52
  • Hisashi Kato, Yozo Nakazawa, Yumi Kurokawa, Hirokazu Kashiwagi, Yoichiro Morikawa, Daisuke Morita, Fumiaki Banno, Shigenori Honda, Yuzuru Kanakura, Yoshiaki Tomiyama. Human CalDAG-GEFI deficiency increases bleeding and delays alpha IIb beta 3 activation. BLOOD. 2016. 128. 23. 2729-2733
  • Satoko Fujita, Hirokazu Kashiwagi, Takuji Tomimatsu, Shoichi Ito, Kazuya Mimura, Takeshi Kanagawa, Masayuki Endo, Tomomitsu Miyoshi, Yasushi Okamura, Yoshihiko Tani, Yoshiaki Tomiyama, Tadashi Kimura. Expression levels of ABCG2 on cord red blood cells and study of fetal anemia associated with anti-Jr(a). TRANSFUSION. 2016. 56. 5. 1171-1181
more...
MISC (94):
  • Yoichiro Morikawa, Hisashi Kato, Keigo Akuta, Hirokazu Kashiwagi, Shigenori Honda, Yuzuru Kanakura, Yoshiaki Tomiyama. The Association of PAR4 Polymorphism with Human Platelet Reactivity in Japanese. BLOOD. 2016. 128. 22
  • M. Sakuragi, S. Hayashi, M. Maruyama, O. Kabutomori, T. Kiyokawa, K. Nagamine, H. Kato, H. Kashiwagi, Y. Kanakura, Y. Tomiyama. Clinical significance of IPF% or RP% measurement in distinguishing primary immune thrombocytopenia from aplastic thrombocytopenic disorders. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015. 13. 868-869
  • H. Kato, Y. Nakazawa, H. Kashiwagi, S. Tadokoro, Y. Morikawa, D. Morita, Y. Kurokawa, Y. Kanakura, Y. Tomiyama. Severe bleeding tendency and impaired platelet function in a patient with CalDAG-GEFI deficiency. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015. 13. 225-225
  • Kazunobu Kiyomizu, Hirokazu Kashiwagi, Shinji Kunishima, Fumiaki Banno, Hisashi Kato, Youichiro Morikawa, Seiji Tadokoro, Koichi Kokame, Shigenori Honda, Toshiyuki Miyata, Yuzuru Kanakura, Yoshiaki Tomiyama. alpha IIb( R990W), a Constitutive Activating Mutation of Integrin alpha IIb beta 3, Knock-in Mice Show Macrothrombocytopenia with Impairment of Platelet Function. BLOOD. 2014. 124. 21
  • Yoshiaki Tomiyama. Eliminate dark side from antiplatelet therapy. BLOOD. 2014. 123. 17. 2599-2601
more...
Books (1):
  • Platelet membrane proteins as adhesion receptors
    Platelets om Thrombotic and Non-thrombotic Disorders, Combridge University Press 2002
Education (2):
  • - 1981 Osaka University Faculty of Medicine
  • - 1981 Osaka University Faculty of Medicine
Professional career (2):
  • (BLANK)
  • (BLANK)
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