J-GLOBAL ID:200901087466125373   Update date: Nov. 05, 2015


Affiliation and department:
Homepage URL  (1): http://www.cc.kyoto-su.ac.jp/~fmotojim/index-j.html
Research field  (3): Structural biochemistry ,  Functional biochemistry ,  Biophysics
Research keywords  (1): Biochemistry
Research theme for competitive and other funds  (1):
  • 2003 - Analysis of protein folding by molecular chaperone GroEL/ES
MISC (4):
Books (4):
  • Hydrophilic residues at the apical domain of GroEL contribute to GroES binding but attenuate polypeptide binding
    Biochem. Biophys. Res. Commun. 2000
  • Discrimination of ATP, ADP, and AMPPNP by chaperonin GroEL: hexokinase treatment revealed the exclusive role of ATP
    J. Biol. Chem. 2003
  • Substrate polypeptide presents a load on the apical domains of the chaperonin GroEL
    Proc. Natl. Acad. Sci, USA 2004
  • Determination of the number of active GroES subunits in the fused heptamer GroES required for interactions with GroEL
    Journal of Biological Chemistry 2008
Lectures and oral presentations  (7):
  • Polypeptide in the chaperonin cage partly protrudes out and then folds inside or escapes outside.
    (The 3rd international symposium on Protein Community 2010)
  • Tethering mechanism of chaperonin
    (Cold Spring Harbor Symposium, Suzhou, China 2011)
  • Chaperonin changes protein folding by regulation of hydrophobic residues
    (新学術領域研究国際シンポジウム”Molecular Science of Fluctuations toward Biological Functions” 2012)
  • シャペロニンの新しい作用機構
    (第13回日本蛋白質科学会年会 2012)
  • シャペロニン援助フォールディングにおける揺らぎ制御の役割
    (新学術領域「揺らぎと生体機能」「水和とATP」合同公開シンポジウム 2012)
Education (1):
  • - 2000 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
Professional career (2):
  • Master of Science (Tokyo Institute of Technology)
  • Doctor of Science (Tokyo Institute of Technology)
Work history (4):
  • 2000 - 2001 Tokyo Institute of Technology Chemical Resources Laboratory
  • 2001 - 2003 Howard Hughes Medical Institute Postdoctral associate
  • 2003 - 2005 Tokyo Institute of Technology Chemical Resources Laboratory Assistant professor
  • Kyoto Sangyo University Faculty of Life Sciences, Department of Molecular Biosciences Assistant Professor
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