Hattori Kotaro

ハットリコウタロウ | Hattori Kotaro

Affiliation and department：

Research field (2)： Molecular biology , Psychiatry

Research keywords (4)： Neuropsychiatric disorders , Cerebrospinal Fluid , Biomarker , Biobanking

Research theme for competitive and other funds (10)：

2023 - 2027 Stratification of depression based on lysophospholipid metabolic disorders and innovative development of novel antidepressants
2019 - 2022 Research on molecular and brain basis for sensorimotor gating dysfunction
2014 - 2017 Development of cerebrospinal fluid miRNA marker for psychiatric disorders
2013 - 2016 Development of biomarkers for functional psychoses based on multiple omics analyses
2010 - 2012 Development of a new therapeutic target molecule for schizophrenia from antipsychotics signaling

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Papers (156)：

Takako Enokida, Kotaro Hattori, Miho Ota, Megumi Tatsumi, Shinsuke Hidese, Noriko Sato, Mikio Hoshino, Hiroshi Kunugi. Correlation between myelin basic protein levels in cerebrospinal fluid and motor speed in patients with schizophrenia. Neuropsychopharmacology Reports. 2024
Takako Enokida, Nanako Yoshida, Megumi Tatsumi, Shinsuke Hidese, Yu-ichi Goto, Mikio Hoshino, Hiroshi Kunugi, Kotaro Hattori. Neuronal autoantibodies in the cerebrospinal fluid of 148 patients with schizophrenia and 151 healthy controls. Heliyon. 2024. 10. 10. e30695-e30695
Hiroaki Hori, Fuyuko Yoshida, Ikki Ishida, Junko Matsuo, Shintaro Ogawa, Kotaro Hattori, Yoshiharu Kim, Hiroshi Kunugi. Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis. Journal of affective disorders. 2024. 349. 244-253
Risa Yamada, Takeshi Fujii, Kotaro Hattori, Hiroaki Hori, Ryo Matsumura, Tomoko Kurashimo, Naoko Ishihara, Sumiko Yoshida, Tomiki Sumiyoshi, Hiroshi Kunugi. Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders. Clinical Psychopharmacology and Neuroscience. 2023. 21. 2. 296-303
Yuya Fujita, Shigeru Iwata, Shinsuke Hidese, Sayuri Ishiwata, Satoru Ide, Hiroaki Tanaka, Koshiro Sonomoto, Yusuke Miyazaki, Shingo Nakayamada, Atsuko Ikenouchi, et al. Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus. Rheumatology. 2023

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MISC (60)：

大盛航, 可野邦行, 服部功太郎, 梶谷直人, 岡田麻美, 朴秀賢, 功刀浩, 青木淳賢, 竹林実. 大うつ病性障害および統合失調症における脳脊髄液リゾホスファチジン酸ドコサヘキサエン酸(LPA-DHA)の減少. 精神神経学雑誌. 2022. 124. 4付録. S-641
高松岳矢, 柳久美子, 馬目陽子, 小金渕佳江, 李俊錫, 當山奏子, 佐藤万仁, DIMITAR Dimitrov, 原(宮内)央子, 長谷川実奈美, et al. Genetic study of Okinawan large pedigree with bipolar disorder and recurrent depressive disorder: the integrated approach of genome sequencing and induced pluripotent stem cell technology. 日本神経精神薬理学会プログラム・抄録集. 2020. 50回・42回・4回. 217-217
池田匡志, 高橋篤, 鎌谷洋一郎, 桃沢幸秀, 齋藤竹生, 近藤健治, 島崎愛夕, 川瀬康平, 作佐部太也, 岩山佳美, et al. Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect(和訳中). 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集. 2019. 29回・49回. 124-124
橋本雅史, 岩崎真樹, 服部功太郎, 飯島圭哉, 齋藤貴志, 齊藤祐子, 松村亮, 横田悠季, 中川栄二, 吉田寿美子, et al. NCNPてんかんバイオバンクの試み. てんかん研究. 2019. 37. 2. 604-604
Norie Koga, Jun Ogura, Fuyuko Yoshida, Kotaro Hattori, Hiroaki Hori, Emiko Aizawa, Ikki Ishida, Hiroshi Kunugi. Altered polyunsaturated fatty acid levels in relation to proinflammatory cytokines, fatty acid desaturase genotype, and diet in bipolar disorder. Translational psychiatry. 2019. 9. 1. 208-208

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Lectures and oral presentations (20)：

The change of Cocaine- and amphetamine-regulated transcript (CART) peptide levels in human cerebrospinal fluid (hCSF) of major depressive disorder (MDD) and the role of CART to modulate basal anxiety-related behaviors in rats.
(2014 Society For Neuroscience)
Effect of single ketogenic diet containing medium chain triglycerides on cognitive functions in elderly adults
(30th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY)
Evaluation of plasma cerebrospinal fluid G72 protein levels and their correlations with psychiatric symptomas in schizophrenia and major depression
(30th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY)
Altered balance between monoamine metabolites in human cerebrospinal fluid with major depressive disorder
(30th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY)
Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder
(30th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY)

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Education (3)：

- 2001 Chiba University
- 1995 Chiba University School of Medicine
- 1995 Chiba University Faculty of Medicine

Professional career (1)：

M. D., Ph. D. (Chiba University)

Work history (7)：

2019/01 - 現在 National Center of Neurology and Psychiatry Department of Bioresources, Medical Genome Center Director
2005 - 現在国立精神・神経センター神経研究所室長
2001 - 2004 Postdoctral Fellow of Japan Science and Techonology
2004 - 大阪大学生命機能研究科研究員
2004 - - Postdoctral Fellow of Osaka University

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Committee career (1)：

2016/03 - 現在 Technical Committee 276, International Standardization Organization Expert

Association Membership(s) (3)：

日本生物学的精神医学会 , 日本精神神経学会 , 日本神経科学学会

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